Neurons + Function + Replaceability
Structure of Neuron + Function
Presynaptic Cell vs Postsynaptic Cell & EPSP vs IPSP
Depolarization vs Hyperpolarization + Which Stage + Which Ions
Depolarization: less negative = more positive charged neuron. Occurs during depolarization, threshold, rising phase by opening sodium channels letting in +sodium & closing potassium channels keeping +potassium
Hyperpolarization: more negative charged neuron. Occurs during undershoot, refractory phase, stays negative resting phase. Sodium channels are opening & closing to keep out & let out +sodium, potassium channels open to let out +potassium
Glial Cell + Function
Glial Cells (glue): same number as neurons, protective scaffolding, sending healing chemicals, clears away debris, create new neurons to heal spinal cord injuries, digest dead, glue of communication between neurons, more accurate transmissions, produces myelin sheaths
Draw + Explain steps for Action Potential to Occur
Action Potential: within cell process carries information through nervous system, electrical signal that is conducted along the length of an axon to the synapse, massive momentary massive reversal of membrane potential, all-or-none response, generating a release of electricity triggering the release of neurotransmitters.
See drawing on Ipad
7 Major Transmitters
Synapse
Synapse: between cell process, when an action potential reaches the synaptic terminal of the axon it becomes positively charged, releasing neurotransmitters from vesicles fused to cell membrane into the synaptic cleft, diffusing rapidly & binding to the receptors in the membrane of the dendrites or cell body of postsynaptic cell.
Each type of receptor binds to a specific type of neurotransmitter (lock & key), causing specific channels of the postsynaptic membrane to open
Ions flow across the cell membrane along concentration gradients causing synaptic potentials which might not travel far and after awhile fade balancing out signal becoming lost or reach far enough to reach threshold
Neurotransmission: chemical potential between neurons, either to excite or inhibit postsynaptic neuron
Many simulations, excitatory & inhibitory, from different channels can occur, at the same time too
Why amount of NT matters + How to Regulate Amount of Neurotransmitters in Synaptic Cleft + Drugs
More of the NT means more signal is more likely to be continued on & concentration is controlled by
Too much too little can cause mental illnesses
Psychoactive Drugs & Synaptic Transmission: Drugs impact receptor binding lock & key or influence concentration of NT in the synaptic cleft is a NT
- Agonists: increase or mimic effect of neurotransmitter, overloading receptors, reducing painful responses
- Antagonists: block or decrease effect of a neurotransmitter, fake neurotransmitters jamming receptors
2 Types of Axonal Transmission + Draw Process
See Ipad Drawing
Neural Plasticity + 3 Circumstances it Occurs
Plasticity: the nervous system’s ability to change over time
Early Development: the most flexible not fully matured until early adulthood, adaptable to the physical & cultural diverse environments. Network of neurons in the brain changes over the course of development in 4 primary ways:
- Growth of dendrites & axons
- Synaptogenesis, the formation of new synapses
- Pruning, consisting of the death of certain neurons & the retraction of axons to remove connections that aren’t useful, streamline neural organization enhancing communication (as many as 70%)
- Myelination, the insulation of axons with a myelin sheath
Learning: formation of new synapses, generating increased connections & communication among neurons
- Potentiation: strengthening of existing synaptic connections so that neurotransmitters released into synapses produce stronger & more prolonged response from neighboring neurons.
- Structural Plasticity: changes in the shape of neurons critical for learning & adapting to environments
Injury & Degeneration: NS doesn’t change enough → permanent paralysis & disability. Certain brain regions can take over functions previously performed by others
- Neurogenesis: creation of new neurons in the adult brain
Peripheral Nervous System + Major Divisions + Functions
Somatic Nervous System: interaction with external environment
- Afferent Nerves: sensory
- Efferent Nerves: motor
- Reflex Arc connects these 2 instantaneously
Autonomatic Nervous System: regulation of internal environment
- Afferent Nerves: sensory
- Efferent Nerves: motor
- Sympathetic: mobilize energy in threatening situations
- Parasympathetic: conserving energy in calm
Spinal Cord + Reflexes + Function
Spinal Cord: conveys info between brain & rest of body
Sensory nerves: carries signals from body to brain
Motor nerves: carry signals from brain to body
Reflex Arc: connecting sensory neurons to interneurons to motor neurons automatically within the spinal cord without reporting back to the brain. For immediate action when the situation is life threatening
Major Brain Structures
Forebrain: controls highest level of complex cognitive, emotional, sensory & motor function divided into
- Cerebral Cortex: responsible for most complex aspects of perception, emotion, movement, & thought
- Subcortical Structures:
Midbrain: area important for tracking & reflexes toward sensory stimuli, regulates sleep & arousal, controls gross motor movements
Hindbrain: area that coordinates info coming into & out of the spinal cord
Structures Within Cerebral Cortex
Subcortical Structures
Hindbrain Structures
Reticular Formation/Activation System: responsible for regulation of sleep, wakefulness & arousal, connects forebrain to cerebral cortex, key role in arousal, damaged=coma, selective attention
Medulla: extension of spinal cord that coordinates heart rate, circulation & respiration, death
Cerebellum: largest structure of the hindbrain, controls fine motor skills, precision. Coordination, smooths out movement, balance
Pons (bridge): structure that relays info from the cerebellum to the rest of the brain, key role in sleep & dreaming, rate of breathing
Brain Stem Structures + Function
Midbrain & Hindbrain
Function: basic bodily functions
Contralateral Control + Split Brain Studies
Contralateral Control: right & left lobes control opposite hemispheres of the body
Split Brain Studies: cutting the corpus callosum leads to inability to say or pick up the object they see on the left or right of a screen, showing lateralized function; how the two hemispheres enact different functions & contralateral control
Corpus Callosum: connects left & right hemisphere instantaneously
Lateralized Function: left & right brain hemispheres have divided functions not personality, left (Fine-tuned language skills+Actions), right (Coarse language skills+visuospatial skills)
Optic Chiasm + Draw Cat Dog
Optic Chiasm: point where optic nerves from the inside half of each eye cross over & project ot the opposite half of the brain
See Ipad drawing
Hormones vs Neurotransmitters
Hormones differs from neurotransmitters in that they’re carried through bloodstream, slow in their actions & its effects last longer
Chromosomes + Genes
Chromosomes (46): trillions of combinations, contain strands of DNA (Deoxyribonucleic acid) that carry genetic info
Genes: sections of DNA that contain hereditary info to replicate+reproduce
Allele: one of two or more alternative forms of a gene
Homozygous: when two alleles of a gene in the specific pair are the same
Heterozygous: when the two alleles of a gene in the specific pair are different
Dominant (E): attributes of the dominant allele is the one that is expressed in a heterozygous pair
Recessive (e): the attributes of the recessive allele is maskin in a heterozygous pair
Genotype: a person’s genetic makeup allelic combinations
Phenotype: person’s genotype is manifested in observable characteristics
Monogenic Inheritance: trait determined by one pair of genes
Polygenic Inheritance: trait is determined by the combination of more than one pair of genes
Behavioral Genetic Designs
Measuring influence of heritability, presence or absence of a trait among different relatives
Why Study Genes + Heritability + Environmentability
Why Study Genes: to understand how much genes & environment affect differences in behavior between individuals
Heritability: the extent to which genes contribute to differences in a trait among individuals. Ratio/Proportion of phenotypic variance attributable to genetic variance
Ranges from 0.0 (genes do not contribute at all/religion) to 1.0 (genes are the only reason for individual differences/eye color)
Environment Ability: proportion of phenotypic variance attributable to environmental variance
Heritability + Environmentability = 1