4 features of Neuroleptic Malignant Syndrome + common meds involved (3)
Neuroleptic malignant syndrome Mx steps in ED (5)
Exam: Outpatient management of acute psychosis- acutely psychotic, psych review 2-3days, not at high risk?
-> If possible delay anti-psychotic to allow for assessment and diagnosis
-> If interim Rx needed for acute agitation = oral diazepam 5-10mg Q4H (Max40mg daily)
KFP: DDx for psychotic symptoms (4+4+4)
3 primary psychotic disorders that differ with timing?
KFP: Hx to assess risk of suicide in patient with SI, but no intent or plan? (6)
KFP: Pt with depressive symptoms, also has better periods. Hx to assess possibility of mania/Type 2 Bipolar (5)
Possible AEs with lithium use (5)
KFP. 28F presents in clear mania. Mx actions (3)
Pharmacological management of acute mania (2)
Anti-psychotic PLUS mood stabliser
eg. olanzapine + lithium
Anti-psychotic for acute mania symptoms, and stop once settles
Concurrent mood stabliser for long term
Safest anti-depressant for pregnancy
Sertraline
48M, history of HTN, hypercholesterolaemia and schizophrenia. On perindopril, atrovatastatin and clozapine. Presents with fever 38.2, unclear focus. Co-incidentally had FBE yesterday which was normal. What needs to be considered and investigated?
Clozapine AE-
- neutropaenia +- myocarditis
Needs urgent ECG, trop + CRP if present with fever >38
KFP: Examples of drugs associated with serotonin syndrome (1+4)
3 features of serotonin syndrome
anyone CAN get serotonin syndrom
1. Cognitive - agitiation, confusion
2. Autonomic - hypertension, tachycardia, fever
3. Neurological - hyperreflexia, tremor, seizure
3 pharma options for alcohol dependency with main contraindications or consideration?
Management of acute insomnia in patient who otherwise seems stable - eg. grieving widow, that doesnt have high risk features?
Short course temazepam with early follow-up ~1wk
Other options - zolpidem or zopiclone
3 key treatment options for PTSD
5 general principles of trauma informed care
Features of adjustment disorder (3)
Basic diagnostic criteria for mania, as opposed to hypomania (4)
Drugs that can affect lithium level
Think triple whammy
- ace-I, NSAIDs, diuretics
KFP: Aspects on history that support primary psychotic disorder (7)
KFP: Possible organic causes of psychotic presentation (7)
KFP: Side effects of anti-psychotics (4+3)