Management of less severe depression?
1st line - Guided self help (unless patient’s preference to start SSRI first)
2nd line - SSRI, group CBT, individual CBT, group exercise
SSRIs (fluoxetine, citalopram, sertraline, paroxetine, and escitalopram)
(take note that sertraline can increase the risk of suicidal ideation and self harm so weekly follow up for the first few months)
Management of more severe depression?
1st line - CBT + SSRI
2nd line - counselling, guided self help, group exercise, interpersonal psychotherapy
How long should antidepressants be taken for after remission of symptoms?
6 months
In a patient taking NSAIDS, if you prescribe an SSRI, what should you also prescribe and why?
PPI as there is an increased bleeding risk
Treatment for acute mania?
What is given for mood stabilisation?
(bipolar disorder)
STOP antidepressants
start antipsychotics e.g. risperidone, quetiapine, olanzapine
2nd line - alternate antipsychotic as mentioned above
3rd line - add lithium
(Electroconvulsive therapy is used for rapid short term treatment of a prolonged or severe manic episode when other treatments have not worked or the condition is life threatening and catatonia is present)
Lithium given for mood stabilisation (long term bipolar disorder) - if not suitable, atypical antipsychotic e.g. risperidone, quetiapine
What are people with bipolar disorder more at risk of?
2-3 times increased risk of:
Diabetes
Cardiovascular disease
COPD
2 biological symptoms of mania?
Increased energy
Reduced need for sleep - not associated with fatigue
2 cognitive symptoms of mania?
Reduced ability to concentrate
Elevated sense of self esteem
Racing thoughts/flight of ideas
2 psychotic symptoms of mania?
Tangential speech
Hallucinations
Delusions
Treatment for generalised anxiety disorder (include 1st and 2nd line pharmacological)
1st line - Education
2nd line - Low intensity interventions - guided self help
3rd line - High intensity interventions - CBT, SSRI
4th line - Specialist input
1st line - Sertraline
2nd line - Other SSRI (Paroxetine) or SNRI (duloxetine, venlafaxine)
3rd line - Pregabalin
Risk factors for generalised anxiety disorder (3) - including 1 medical condition
History of trauma
Family history
Substance use
Endocrine - HYPERTHYROIDISM phaechromocytoma, cushing’s,
Management of a panic attack?(1st and 2nd line pharmacological)
1) Recognition and diagnosis
2) Treatment in primary care: CBT, medication
3) Review and consider alternative treatment
4) Refer to specialist mental health services
5) Care in specialist mental health services
1st line - SSRI (Sertraline, fluoxetine, paroxetine)
2nd line - If doesn’t work after 3 months/if CI –> Imipramine/Clomipramine (TCA)
3 characteristics of ADHD?
Persistent hyperactivity, impulsivity and inattention
Management of ADHD? What do you need to monitor?
1st line - Psychoeducation + lifestyle (diet and exercise)
2nd line - CAMHS
3rd line - Drug treatment
3 characteristics of someone with autism spectrum disorder
Screening tool for autism spectrum disorder
Childhood autism screening tool (CAST)
Childhood autism rating scale (CARS)
Management of autism spectrum disorder
Applied behavioural analysis
Early denver model - behavioural therapy
ASD preschool programme
(SSRI and antipsychotics can be given to reduce symptoms of repetitive behaviour and aggression)
What tool is used to classify the impairment of OCD?
Y-BOCS
Yale brown obsessive compulsive scale
Management of OCD?
Mild, moderate, severe
Mild - exposure and response prevention (CBT)
2nd line - SSRI (sertraline)
Moderate
- SSRI/TCA/more intensive CBT
Severe
- Referral to secondary care mental health team + CBT + SSRI
4 main symptoms of PTSD?
Avoidant
Negative alterations in mood
Alterations in arousal and reactivity
Mental intrusions
Treatment for PTSD?
If it’s mild and <1 month (acute stress disorder) - watchful waiting
Severe symptoms
- Trauma based CBT + Eye movement desensitisation and reprocessing (EMDR)
2nd line - Sertraline/venlafaxine/risperidone
Treatment for schizoaffective disorder?
Risperidone/quetiapine
CBT
2 risk factors for schizophrenia
Family history
Increased paternal age
Monozygotic twins
Black Carribean
3 prodromal symptoms (must be present for 6 months)
5 active phase symptoms (present for 1 month)
of schizophrenia
Prodromal sx
- Social withdrawal
- Reduced appetite
- Poor concentration
- Sleep difficulty
- Poor memory
Active phase
- Delusions of perception
- Passivity phenomenon
- Auditory hallucination
- Negative symptoms - Alogia (reduced speech and social withdrawal), anhedonia, avolition, affect flattening
- Thought disorder - withdrawal, insertion, broadcasting