What is prevention psychiatry?
Reduction of mental disorders/behavioral problems by identifying risk/protective factors and applying evidence-based interventions.
What is primary prevention?
Preventing illness before it occurs
(e.g. vaccines, diet).
What is secondary prevention?
Early identification and treatment to shorten duration (e.g. screening, EITs).
What is tertiary prevention?
Reducing disability from established illness (e.g. rehab, relapse prevention).
What is Geoffrey Rose’s ‘prevention paradox’?
Population-wide interventions reduce overall disease burden but offer small benefit to each individual.
Types of preventative interventions (IOM 1994)?
Universal (entire population), Selective (high-risk subgroups), Indicated (individuals with subthreshold Sx of early illness).
What are major risk factors for psychiatric disorders?
Biological, psychological/psychosocial, social/environmental.
Who first induced therapeutic seizures for psychosis?
Ladislas von Meduna (1934, camphor-in-oil).
Indications for ECT?
1st line: severe depression, psychosis, high suicide risk, catatonia, pregnancy + severe depression
2nd line: TRD, severe mania, TR schizophrenia/catatonia
Absolute contraindications for ECT?
None.
Common ECT side effects?
Short-term memory loss, retrograde/anterograde amnesia, headache, nausea, confusion.
ECT effectiveness and relapse?
60-80% remission in severe depression, relapse >80% without maintenance.
Maintenance ECT indications?
Early relapse despite drugs, intolerance to meds, patient preference, prior good response.
Electrode placement for ECT?
Bilateral: both temples, 4cm above midpoint between eye and ear
Unilateral: nondominant hemisphere, frontal-parietal
Which drugs increase seizure threshold?
Benzos, barbs, anticonvulsants.
Which drugs decrease seizure threshold?
Antipsychotics, antidepressants, lithium.
How does rTMS work?
Magnetic pulses stimulate cortical neurons without inducing generalised seizures.
Indications for rTMS?
TRD, left DLPFC common target, outpatient, no anaesthesia needed
rTMS side effects?
Site discomfort, transient headache, rare seizure (motor cortex stimulation).
When is psychosurgery indicated?
Severe mood disorder or OCD resistant to all other evidence based treatments, informed consent required
Adverse effects of modern stereotactic psychosurgery?
Headache, nausea, brief confusion; long-term effects rare.
Common psychosurgical procedures?
Subcaudate tractotomy, anterior cingulotomy, limbic leucotomy, anterior capsulotomy.
DBS mechanism and indications?
Electrodes stimulate brain regions via pacemaker, used in Parkinson’s disease, OCD, TRD, Tourette’s.
DBS complications?
Infection, haemorrhage, seizures, neuropsychiatric effects, hardware issues