PUD

Question 1

etiologies of PUD

Answer 1

• H. Pylori (majority of PUD)
• chronic NSAID/ ASA use

Question 2

clinical presentation of PUD

Answer 2

• Epigastric pain
• dyspepsia

Question 3

duodenal ulcer presentation

Answer 3

pain relieved with eating

Question 4

gastric ulcer

Answer 4

pain worsened with eating

Question 5

Diagnostic testing for PUD

Answer 5

• Endoscopy is the gold standard
  H pylori antibody testing/antigen
  urea breath test- quick results (false negative w/ PPIs, abx and bismuth compounds)

Question 6

Treatment of PUD

Answer 6

oral PPI or H2RA therapy

Question 7

Eradication of H Pylori treatment

Answer 7

2 antibiotics, 1 PPI, bismuth
Tetracycline 500 mg, metronidazole 250 QID, bismuth 525 mg QID, and PPI (first line) (omeprazole 20 mg)

Second line: Clarithromycin 500 mg BID, amoxicillin 1g BID and PPI

Question 8

sucrafate is used as a

Answer 8

stress ulcer prophylaxis- coats the eroded mucosal surface w/o blocking acid secretion.

Question 9

Educate patient

Answer 9

quit smoking and and to stop alcohol consumption

Question 10

Misoprostol used for

Answer 10

NSAID ulcer prophylaxis

Question 11

________ ulcers tend to perforate into the pancreas causing acute pancreatitis

Answer 11

Duodenal

Question 12

PUD complications

Answer 12

Bleeding ulcers
perforated ulcer

Question 13

transfuse plts if < ____________

Answer 13

50,000