-Nodules- seen on CXR
-Benign: 45-50yo, smoker, new/enlarged lesion, absent/irregular
calcification, irregular margins, >2cm
- Cancer= leading cause of cancer death in US
- Small cell(SCLC): highly correlated with cigarette exposure, central location, neuroendocrine origin, mets usually found on presentation in intrathoracic and extrathoracic sites (brain, liver, bone)
- Non-small cell(NSCLC): most common are adenocarcinoma, SCC, large cell carcinoma. Less likely to metastasize at early stage.
- Adenocarcinoma: Most common lung cancer, peripheral
- SCC: central location
- Large cell: least common
- Nodules: asx or have chronic cough, dyspnea, and SOB.
- Cancer: cough, hemoptysis, dyspnea, wheezing, pneumonia, chest pain, wt loss, possible abnormal resp exam.
- Dx: CXR or CT, FNA for peripheral lesions, bronchoscopy for central lesions
- Tx: Nodules= Surgical resection of nodules that are high risk for malignancy. Otherwise follow with CXR or CT every 3 mos for 1 yr, then every 6mos. SCLC=radiation and chemo. NSCLC= Surgical resection in early stages.