Pyrexia (Unknown Origin)

Question 1

Infective Causes

Answer 1

TB
Abscess
Infective Endocarditis
Osteomyelitis
Pneumonia
UTI
Meningitis/Encephalitis
HIV
Hepatitis
Tropical Infection

Question 2

Systems R/V

Answer 2

Resp
Abdominal
GU
Neurological
Skin
Joints 

Other: weight loss, night sweats, bleeding, rash

Question 3

Travel Hx

Answer 3

Which countries? Dates?

Urban/Rural?

Type of accom?

Question 4

Sexual RF

Answer 4

Sexual intercourse whilst away?

- If yes, full sexual hx

Question 5

Procedures

Answer 5

Hospitalisation

• IV Access
• Blood transfusion

Piercings
IVDU

Question 6

Activities RF

Answer 6

Animal

• bites/close contact
• Farm animals

Contacts

• Others unwell
• Known Diagnosis?

E&D

• High risk foods?
• Unsterile water

Swimming?

• Natural lakes/rivers
• Water rafting, canoing

Question 7

Prevention

Answer 7

Vaccinations?

Malarial prophylaxis?

Question 8

Drug Hx

Answer 8

Immunosupressants
ART
Antimalarials
Recent chemo

Question 9

Malignancy Causes

Answer 9

Lymphoma

Leukaemia

Question 10

Rheumatology

Answer 10

RA
SLE
GCA
PMR
Still's disease

Question 11

Miscellaneous

Answer 11

Drugs
PE
IBD

Question 12

Bedside Ix

Answer 12

Temp

Urine dip

Question 13

Bloods

Answer 13

FBC, UEs, LFTs,
CRP, ESR
amylase
HIV, hepatitis serology
HIV

Autoantibody screen
- ANA, cANCA, anti-CCP, anti-dsDNA, RF

Blood cultures
- 3x for IE

Blood film
- Malaria

Question 14

MC&S

Answer 14

Sputum
Urine
Throat/ear/genital

Question 15

Imaging

Answer 15

CXR
Abdo USS
CT/MRI