1
Q
name one
A
ciprofloxacin
2
Q
what are its uses
A
- eye infections and corneal ulcers
- prevention of secondary menegitis
- dental infection- anthrax
- respiratory infections-psuenomas aeruginosa
- GI infections- travellers diarrhoea, shigella
- UTI
- cystitis
- prostatitis
3
Q
MOA
A
inhibits DNA gyrase and therefore DNA synthesis
4
Q
SE
A
headache, nausea, dizziness
GI upset
hypersensitivity reactions
increased risk of rupture of muscle tendon
prolonged QT interval
decreased seizure and hallucination threshold
5
Q
CI
A
prolonged QT intervals/risk of arrhytmias
children - growing for example
seizures/epileptic
6
Q
DI
A
NSAID- increase risk of seizures
prednisolone increases risk of muscle tendon rupture
theophylline increased risk of convulsions and ciclosprin increased risk of nephrotoxicity
