RABIES

Question 1

What’s the rabies genome?

Answer 1

• ssRNA

Question 2

What is a source of rabies virus transmission?

Answer 2

• Dogs (most common reservoir of human rabies), cats,…

It’s a zoonotic disease

Question 3

How is rabies virus transmitted?

Answer 3

-Lick
- Scratch and
- Bite from infected animals

Question 4

What’s the suitable ante-mortem specimen (lively person specimen) for rabies?

Answer 4

• CFS
• Saliva
• Nuchal Skin biopsy (Section of skin, must be taken from the nape of the neck)

Question 5

What’s the suitable post-mortem specimen (dead person) for rabies?

Answer 5

• Brain specimen

Question 6

What are the 2 types of human rabies presentation?
How do they differ

Answer 6

• Furious rabies presentation: Progresses rapidly as anxiety confusion, and agitation. As the disease progresses, the patient become delirious, behaves abnormally, hallucinates and
  may have a variety of psychiatric symptoms before becoming comatose → death.
• The dumb or “paralytic” rabies: clinically presents similar to poliomyelitis but presents with descending paralysis, coma and death.