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Question 1

What are the effects on serum electrolytes of a thiazide diuretic

Answer 1

can cause a low blood level of potassium, sodium and magnesium, and a high level of calcium

Question 2

What is an example of a thiazide diuretic

Answer 2

Bendroflumethiazide

Question 3

Where should thiazide-type diuretics be avoided

Answer 3

Thiazide-type diuretics should be avoided in:
People with:
-Refractory hypokalaemia.
-Hyponatraemia.
-Hypercalcaemia. 
-Addison's disease.
-pregnant women

Question 4

How do thiazide diuretics work

Answer 4

inhibit sodium reabsorption at the beginning of the distal convoluted tubule

Question 5

Do not use loop diuretics in people with…

Answer 5

• Hypovolaemia and dehydration (with or without accompanying hypotension).
• Severe hypokalaemia or severe hyponatraemia.
• Anuria, acute kidney injury or chronic kidney (CKD) disease due to nephrotoxic or hepatotoxic drugs, or associated with hepatic coma.
• CKD with a creatinine clearance below 30 mL/min/1.73 m2.
• Addison’s disease.

Question 6

Give examples of loop diuretics

Answer 6

Bumetanide, Foresamide, Torasemide

Question 7

how does a loop diuretic work

Answer 7

inhibiting the sodium-potassium-chloride (Na+/K+/2Cl) co-transporter in the thick ascending loop of Henle