Random Neuro

Question 1

What is the classic hallmark of primary progressive aphasia?

Answer 1

Progressive language disturbance, leading to functional impairment with relative preservation of episodic memory and other cognitive domains

Question 2

What is the nonfluent variant of PPA? How does this present?

Answer 2

• motor speech deficit characterized by effortful production of the linguistic units of sound (phonemes)
• effortful, halting speech with inconsistent speech-sound errors and distortions and agrammatism in language production

Question 3

How can the nonfluent variant of PPA be tested for? Why does this work?

Answer 3

• Have pt say caterpillar or artillery rapidly, and repeatedly
• These words are particularly hard to articulate

Question 4

Is comprehension spared with nonfluent PPA?

Answer 4

For simple word sentences, yes. For more complex sentences, no

Question 5

What is the semantic variant of PPA? How does this commonly present?

Answer 5

• impaired single-word comprehension and object naming in the setting of preserved fluency, repetition, and grammar.
• Word-finding difficulty and inability to single word objects

Question 6

True or false: pts with semantic PPA have an inability to understand sentences, but can understand single words fine

Answer 6

False–opposite is true

Question 7

How can the Semantic PPA be tested?

Answer 7

Draw a turtle, dog, bird etc. Pts will leave out specific details of drawing (shell of turtle)

Question 8

What is the logopenic variant of PPA?

Answer 8

Single word retrieval and repetition with errors in speech and naming, but with spared single wrose comprehension and object knowledge, spared motor speech, and absences of agrammatism

Question 9

How are logopenic PPA and nonfluent PPA similar and different?

Answer 9

• Similar in that slow speech, with word-finding pauses
• Slow rate is due primarily due to word findings pauses, rather than difficulties with word production, articulation, or apraxia of speech

Question 10

A pt with PPA tells a story that lacks any sort of detail. What variant of PPA does she have?

Answer 10

Logopenic