Proprietary name?
Zantac
What is the Bp name?
Ranitidine
Uses?
Reduces gastric acidity
Prophylaxis of acid aspiration
Form?
Tablets
Syrup
Injection
Group?
Antacid
Type?
POM
Dosage
OOL 150mg 6hrly
IM 50mg 50-60 mins prior to analgesia
IV inj 20ml over 2 mins
B/F?
Yes
Fetal risk?
Crosses placenta use long term if essential only
For prophylaxis in labour or LSCS
Side effects
Rare - dizzy, rashes
Rarely - Tachycardia
Contra indications
Hypersensitivity
Avoid in clients stabilised on phenytoin and warfarin
Pharmacodynamics
Rapid acting histamine H2 antagonist. Inhibits basal and stimulated secretion of gastric acid, reducing vol and acid and pepsin content of the secretion.
Single 150mg lasts 12 hours.