RBC Abnormalities

Question 1

Rouleaux Formation:short/long stacks of RBC. Seen in all except:
A.Hyperproteinemia 
B.Atypical pneumonia
C.Multiple Myeloma (MM) 
D.Pregnancy

Answer 1

B

Question 2

autoagglutination is commonly seen in the ff except \_\_?
A.hemolytic anemia
B.Mycoplasma pneumonia
C.staphylococcal infections
D.schistosomiasis

Answer 2

D

Trypanosomiasis dapat

Question 3

variation in Hb content is also called as __

Answer 3

Anisochromia

Question 4

Hypochromia is commonly seen in all except
A.iron deficiency anemia
B.rheumatoid arthritis
C.acute infections
D.inflammation

Answer 4

C

Question 5

False about hyperchromic blood
A. Lacks central pallor, blood is too bright red
B. Seen in sickle cell anemia
C. Spherocytes may be detected
D. true state if MCV is elevated

Answer 5

D

MCHC dapat

Question 6

Macrocytic RBC is not seen in
A.B1 deficiency
B.Alcoholism, without liver disease C.Cancer chemotherapy
D.Chronic hemolytic anemia

Answer 6

A

B12 dapat

Question 7

Megaloblastic anemia associated with achlorydia and lack of intrinsic factor necessary for the binding and absorption of vitamin B12.

Identify!

Answer 7

Pernicious anemia

Question 8

RBC is thinner than normal and have colorless center (increased surface area, not proportional to the volume)

Identify

Answer 8

Leptocytes

Question 9

Where are leptocytes not seen?
A.thalassemia
B.obstruction of pancreatic ducts
C.cirrhosis
D.steatorrhea

Answer 9

B

Bile dapat

Question 10

Variation in shape, abnormal shape of cells

Identify

Answer 10

Poikilocytosis

Question 11

Not a direct cause of poikilocytosis
A.structural changes in the cell membrane
B.A metabolic state in the cell C.Hemoglobin molecule abnormality
D.Person’s age

Answer 11

D

Red cell age dapat

Question 12

Identify

Cell with irregular, long, assymettrical projections; specially seen with severe liver disease or post-splenoctomy; seen with rare disorder of abetalipoprteinemia

Answer 12

Acanthocyte

Question 13

Identify

Similar to ring forms of malaria

Answer 13

Babesiosis

Question 14

Identify

Small aggregates of RNAs are seen as small blue dots in the RBC;

Answer 14

Basophilic stippling

Question 15

Elongated, elliptical cell; non-specific when occasionally seen; rare hereditary disorder

Identify

Answer 15

Elliptocyte

Question 16

Identify

Precipitated Hgb seen as a perimembranous blue dot only after supravital staining, seen with some hemoglobinopathies

Answer 16

Heinz body

Question 17

Identify

Small, round deeply basophilic nuclear remnant; seen when spleen is absent

Answer 17

Howell-Jolly body

Question 18

Cells with decreased MCH, typical of iron deficiency

Identify

Answer 18

Hypochromia

Question 19

Cells with increased MCH, typical of megaloblastic anemia

Answer 19

Macrocytic

Question 20

Plasmodium infection seen as ‘ring forms’, stippling and gametocytes, depending upon the species

Identify

Answer 20

Malaria

Question 21

Cells with decreased MCV, typical of iron deficiency anemia and thalassemia

Answer 21

Microcytosis

Question 22

Multiple, tiny iron-containing granular blue dots; seen when spleen is absent and with iron overload

Identify

Answer 22

Pappenheimer body

Question 23

Variation in shape of RBCs

Answer 23

Poikolicytosis

Question 24

The bluish tint to young RBCs with high RNA content

Answer 24

Polychromatophilia

Question 25

Identify Young RBCs with increased RNA content that can be precipitated by supravital staining for identification and enumeration

Answer 25

Reticulocyte

Question 26

Identify Linear aggregation of RBCs that resembles stack of coins; when surface charge is reduced with increased serum protein, particularly increased fibrinogen or globulin

Answer 26

Rouleaux

Question 27

Identify Non-nucleated RBC with stainable iron

Answer 27

Sideroblast

Question 28

Identify Small, round dense cell without central pallor; suggests extravascular (splenic) hemolysis in previously normal persons;

Answer 28

Spherocytes

Question 29

with hereditary spherocytosis there is increased osmotic fragility T or F

Answer 29

T

Question 30

Fragmented, irregularly shaped seen with intravascular hemolysis such as microangiopathic hemolytic anemias (DIC, TTP); Identify

Answer 30

Schistocyte

Question 31

Identify Curved, banana-shaped cell with pointed ends found in sickle cell disease from aggregation of Hgb S

Answer 31

Sickle cell

Question 32

Cell with slit-like central pallor; Identify

Answer 32

Stomatocyte

Question 33

Cell with central and peripheral staining with intervening pallor due to increased redundancy of RBC membrane; seen with liver disease, in some thalassemias and with high Hgb C Identify

Answer 33

Target cell

Question 34

Cell pinched at one end, prominent in myelofibrosis and myelophthisic conditions Identify

Answer 34

Teardrop cell

Question 35

``` Ovalocytes may be seen in: A. Sickle cell anemia B. Thalassemia C. autoimmune hemolytic anemia D. microangiopathic hemolytic anemia ```

Answer 35

A and B

Question 36

``` Spherocytes may be seen in: A. Sickle cell anemia B. Thalassemia C. autoimmune hemolytic anemia D. microangiopathic hemolytic anemia ```

Answer 36

C and D

Question 37

False about echinocytes A. caused by release of substances from glass that changes pH and transform cells into echinocytes B. In stored blood - increase of ATP and biochemical abnormalities in plasma C. Not normally seen in vivo D. Regarded as an artifact

Answer 37

B Decrease dapat

Question 38

Identify: • spicules may be irregularly shaped, unevenly spaced • Seen in renal insufficiency • If seen in PBS should be reported

Answer 38

Burr cell

Question 39

A.Caused by changes in the ratio of plasma lipids (lecithins and sphingomyelins) B. Have irregularly spaced, few pointed spicules or thornlike projections of various lengths and widths to club shaped C. Hereditary and acquired Identify the abnormal RBC

Answer 39

acanthocyte

Question 40

Identify RBC abnormal cell * Elongated, with slit like area of pallor • Hereditary or acquired * May be a result of high cellular sodium and low potassium content * May be retained in the spleen because of abnormality

Answer 40

Stomatocyte

Question 41

Identify RBC abnormal cell * Central area of Hb surrounded by colorless ring and a peripheral ring of Hb * Always acquired (No hereditary) * Membrane surface is increased because of cholesterol and phospholipid loading * Seen in THALASSEMIA

Answer 41

Codocyte

Question 42

``` Serum - Plasma minus ____ A. Fibrinogen B. Thrombin C. WBC D. RBC ```

Answer 42

A