READING ASSIGNMENT: SEROLOGIC TESTS FOR HEPATITIS B VIRUS

Question 1

hepatitis B surface antigen, the envelope protein consisting of three polypeptides

Answer 1

HBsAg

Question 2

antibody to hepatitis B surface antigen

Answer 2

Anti-HBs

Question 3

antibody to hepatitis B core antigen

Answer 3

Anti-HBc

Question 4

antigen associated with the nucleocapsid, also found as soluble protein in serum

Answer 4

HBeAg

Question 5

antibody to hepatitis B e antigen

Answer 5

Anti-HBe

Question 6

• Active HBV infection
• long-term carrier (after 6 months of acute infection) incubation period

Answer 6

HBsAg

Question 7

• Appears early in the course of the disease
• Acute infection
• Confirms the diagnosis of acute HBV in cases where HBsAg is not detected and anti-HBs has not
  yet appeared

Answer 7

IgM anti-HBc

Question 8

Convalescence or immune status

Answer 8

anti-HBs

Question 9

• Chronic infection
• High infectivity

Answer 9

HBeAg