recert Flashcards

(437 cards)

1
Q

What are the initial symptoms of Central Retinal ARTERY occlusions?

A
  • Painless vision loss
  • CHERRY-RED macula
    • APD

APD stands for Afferent Pupillary Defect.

Instead, the fovea receives its blood supply from the underlying choroid, which is a separate, rich vascular network supplied by the ciliary arteries.
• Because the choroidal circulation is typically not affected by the central retinal artery occlusion, the fovea remains perfus

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2
Q

What are the initial symptoms of Central Retinal VEIN occlusions?

A
  • Painless vision loss
  • BLOOD and THUNDER appearance
  • Swollen optic disc
  • COTTON-WOOL spots
    • APD

APD stands for Afferent Pupillary Defect.

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3
Q

Normal infant crying is defined as crying for ≤ 3 hrs a day, usually more in which time frame?

A

Evenings (3pm - 11pm)

This is considered a normal behavior in infants.

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4
Q

Suspect Fentanyl overdose over Heroin if a patient requires multiple rounds of _______.

A

naloxone

Naloxone is an opioid antagonist used to reverse opioid overdoses.

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5
Q

What percentage of acute MI will develop a LEFT ventricular aneurysm?

A

20%

Most likely due to LAD artery occlusion.

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6
Q

In EKG, LVH is indicated by which measurements?

A

V1/V2 S-wave + V5/V6 R-wave
> 35 mm in > 35yo

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7
Q

What does fixed skin staining or blistering indicate?

A

Late limb ischemia

Revascularization of the limb could cause life-threatening reperfusion injury.

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8
Q

What is poikilothermia?

A

Cool limb

It is a condition where a limb cannot regulate its temperature.

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9
Q

Peripheral edema as a manifestation of heart failure is rare in which population?

A

Infants

Newborn murmurs are common in this age group.

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10
Q

What are the characteristics of a safe murmur in newborns?

A
  • HIGH-PITCHED mid-systolic murmur at LEFT upper sternal border (Peripheral pulmonary stenosis)
  • LOW-PITCHED systolic murmur at LEFT lower sternal border (Still’s murmur)

The latter is often described as musical and is louder in the supine position.

https://www.youtube.com/watch?v=KW-twmAofv4

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11
Q

What is the most common cause of congenital stridor?

A

Laryngomalacia

It presents at birth or within the first few weeks of life and is rarely life-threatening.

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12
Q

What is the most common infant skull fracture?

A

Parietal fracture

The temporal fracture is the most common associated with ICH.

parietal = green
temporal = orange ( most common w ICH

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13
Q

What is the onset and corneal condition in acute closed angle glaucoma?

A
  • ACUTE onset
  • STEAMY cornea due to edema

Patients may also experience halos around lights.

Open-angle glaucoma is the most common type, characterized by a gradual increase in eye pressure without noticeable symptoms until significant vision loss occurs. In contrast, closed-angle glaucoma is a medical emergency that occurs when the drainage angle in the eye becomes blocked, leading to a rapid increase in eye pressure and symptoms like severe eye pain, nausea, and blurred vision.

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14
Q

What are the characteristics of OPEN-angle glaucoma?

A
  • Binocular
  • GRADUAL ONSET
  • Painless due to the gradual onset, the eye can adapt
  • WHITE conjunctiva
  • Mildly elevated IOP (>21mmHg)
  • Decreased peripheral vision with normal central vision

IOP stands for Intraocular Pressure.

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15
Q

What are the symptoms of traumatic iritis?

A
  • Deep, aching eye pain
  • Decreased visual acuity
  • Injection of the limbus
  • Photophobia
  • Cells and flare in the anterior chamber

Treatment includes topical cycloplegic agents and oral pain medications.

Common Treatment Methods
Medications
Steroid Eye Drops: Glucocorticoid medications are commonly prescribed to reduce inflammation. Examples include prednisolone acetate.
Dilating Eye Drops: These help relieve pain and prevent complications by dilating the pupil. They stabilize the blood-aqueous barrier and reduce discomfort.

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16
Q

Loss of pacemaker capture on ECG in the setting of hiccups suggests what?

A

Lead dislodgment

This is a critical finding in monitoring pacemaker function.

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17
Q

If a button battery is in the stomach and the patient is asymptomatic, what should be done?

A

D/c home with repeat x-rays

Monitoring is essential to ensure no complications arise.

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18
Q

What type of hemangioma can resolve spontaneously after delivery in pregnant patients?

A

Capillary hemangioma

These are benign vascular tumors.

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19
Q

What can cause auricular perichondritis?

A
  • Trauma
  • Ear surgery
  • High ear piercing in the upper cartilage

This is an unusual infection affecting the ear.

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20
Q

What does a Meckel scan determine?

A

Presence of ectopic gastric tissue outside of the intestines

It uses a radiolabeled material for detection.

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21
Q

What is a key indicator of DIGOXIN toxicity?

A

Hyperkalemia

This occurs due to poisoning of sodium-potassium ATPase.

K can not get pulled into cells and thus collects in the Extracellular space

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22
Q

What is the smell associated with POISON HEMLOCK?

A

Mouse urine smell

It contains nicotine-like alkaloids and all plant parts are poisonous.

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23
Q

What is the smell associated with WATER HEMLOCK?

A

Carrot smell

It contains cicutoxin, which affects GABA receptors.

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24
Q

Which worms cause Fe deficiency anemia?

A
  • Necator americanus (hookworm)
  • Trichuris trichiura (whipworm)

These parasites can lead to anemia through blood loss.

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25
What is the treatment for **Strongyloides stercoralis**?
* Ivermectin * Albendazole ## Footnote Hyperinfestation can be fatal in immunocompromised patients.
26
What are the symptoms of **Ascaris lumbricoides** infection?
* Cough due to larvae migrating through lungs * Eosinophilic pneumonia (Loffler syndrome) * SBO due to collection of worms in gut ## Footnote Treatment includes ivermectin, albendazole, or mebendazole.
27
What is the most common worm infection in the US?
Enterobius vermicularis (PINWORMS) ## Footnote It causes anal pruritus and spreads in families.
28
What is the cause of **Trichinosis**?
Raw/undercooked meat, usually from wild game ## Footnote Symptoms include diarrhea, abdominal pain, and eyelid edema. How it Spreads to Humans: When a person eats infected, undercooked meat, the stomach acid digests the meat, releasing the Trichinella larvae from their protective cysts.  1. The larvae invade the wall of the small intestine and mature into adult worms.  2. The adult female worms then produce new larvae.  3. These new larvae travel through the bloodstream and ultimately migrate to muscle tissue throughout the body, where they burrow in and form new, hard cysts, remaining alive for years.
29
What does **Necator americanus** cause?
Anemia due to penetration into intestinal mucosa causing bleeding ## Footnote Treatment includes ivermectin or mebendazole.
30
What is **Cutaneous Larva Migrans**?
Hookworm larvae penetrate feet from contaminated animal feces ## Footnote It results in pruritic serpiginous tracks.
31
What is the vector for **Hantavirus** (subtype Sin Nombre virus)?
Deer mouse ## Footnote It can cause Hantavirus pulmonary syndrome (HPS).
32
What are some **drugs** associated with **TCA poisoning**?
* TCA * Cocaine * Venlafaxine * Diphenhydramine * Lamictal ## Footnote These substances can lead to toxicity and require careful management.
33
What are the **three symptoms** of **Wernicke’s encephalopathy**?
* Oculomotor changes * Ataxia * Confusion ## Footnote Treatment includes Thiamine and Magnesium, which is a cofactor for thiamine transketolase.
34
What is **orchitis** and what viral infections are commonly associated with it?
Inflammation of the testis, commonly associated with *Epstein-Barr virus* or *mumps* ## Footnote Bacterial causes include *Klebsiella*, *E. coli*, and *Pseudomonas*, all of which are encapsulated bacteria.
35
In osteoarthritis (OA), what are the **NODES** found in the **PIP** and **DIP** joints?
* Bouchard nodes (PIP) * Heberden nodes (DIP) ## Footnote DIP joint involvement is characteristic of OA.
36
What is the characteristic **swelling** in **rheumatoid arthritis (RA)**?
Swelling of *MCP* and *PIP* joints, sparing DIP joints ## Footnote This distinguishes RA from OA.
37
What is **malignant hyperthermia** and its treatment?
An inherited condition with inappropriate release of calcium from the sarcoplasmic reticulum in skeletal muscle; treated with *dantrolene* ## Footnote Dantrolene antagonizes the excessive release of calcium.
38
What is the treatment for **HACE**?
dexamethasone 8mg then 4mg q6hrs ## HACE stands for High Altitude Cerebral Edema.
39
What is the treatment for **HAPE**?
Nifedipine ER 30mg PO q 12 ## Footnote HAPE stands for High Altitude Pulmonary Edema.
40
What is the treatment for **acute mountain sickness (AMS)**?
Acetazolamide ## Footnote Acetazolamide can lead to non-anion gap metabolic acidosis and increase respiratory rate.
41
What is the characteristic pain of a **cluster headache**?
Sharp, stabbing pain in one eye lasting 15 minutes to several hours ## Footnote Treatment includes NRB (non-rebreather mask).
42
What are some **risk factors** for **renal cell cancer**?
* Alcohol consumption * Cigarette smoking * Genetic factors * Hypertension * Obesity * von Hippel-Lindau disease ## Footnote These factors contribute to the development of renal cell carcinoma.
43
What are **lateral anal fissures** associated with?
Systemic disease ## Footnote This can indicate underlying health issues.
44
True or false: **Pacing** is safe for patients with severe hypothermia.
FALSE ## Footnote Pacing can induce ventricular fibrillation in these patients.
45
What is **erythema nodosum (EN)** and its characteristics?
Panniculitis due to vasculitis, tender and mobile, changes from purple to yellow ## Footnote Differential diagnosis includes *HLA-B27*, sarcoidosis, IBD (UC), strep, TB, URI, medications, and idiopathic causes.
46
What is **Henoch-Schonlein Purpura (HSP)**?
Vasculitis affecting dependent areas, often with arthritis and ileoileal intussusception ## Footnote **50% have microscopic hematuria and proteinuria** ## Footnote tx: steroids -—— now more commonly called IgA Vasculitis (IgAV), is an immune complex-mediated, small-vessel leukocytoclastic vasculitis. —_— Antigen Encounter: A pathogen enters the body through a mucosal surface (e.g., in the food or air). 2. B-Cell Activation: Immune cells capture the antigen and present it to B-cells (the cells that make antibodies). 3. Class Switching: The B-cells undergo an immune process called class switching, where they switch from producing an initial antibody type (like IgM) to specifically producing the \alpha (alpha) heavy chain that defines IgA.  4. Maturation and Secretion: The activated B-cells mature into IgA-producing plasma cells that reside just beneath the epithelial lining, constantly secreting IgA into the mucus layer to provide a continuous shield.
47
What is **pyoderma gangrenosum** characterized by?
Ulcerations with pathergy, where minor trauma leads to exaggerated ulceration of skin ## Footnote This condition is often associated with systemic diseases. PG is the prototypical example of a Neutrophilic Dermatosis, characterized by a sterile, dense infiltration of neutrophils into the skin that causes rapid tissue destruction and ulceration. key clinical phenomenon is pathergy, which is defined as the development of new PG lesions at sites of minor skin trauma (e.g., needle sticks, biopsies, surgical incisions). This highlights the hyper-reactive state of the patient's immune system, where even a trivial injury can trigger the full, uncontrolled neutrophilic cascade
48
What is the most common cause of **pneumonia** in **cystic fibrosis**?
Staph aureus ## Footnote 80% of cystic fibrosis patients are colonized with *Pseudomonas aeruginosa* by age 18.
49
What are the three parts of the **uvea**?
* Anterior: Iris * Intermediate: Ciliary body * Posterior: Choroid ## Footnote The choroid is the vascular layer between the retina and sclera.
50
What is **iritis** and its treatment?
Anterior uveitis; treated with cycloplegic drops (cyclopentolate or tropicamide) ## Footnote Follow-up with an ophthalmologist in 24-48 hours.
51
What is **post extraction alveolar osteitis** commonly known as?
Dry socket ## Footnote Treatment includes warm water mouth rinse or chlorhexidine 0.12% oral rinse.
52
What is **hydrofluoric acid** classified as?
Weak acid ## Footnote It penetrates skin easily and binds with Ca2+ and Mg2+.
53
What does **cyanide** poisoning affect in the body?
Oxidative phosphorylation, preventing O2 usage, leading to increased O2 levels in venous blood ## Footnote Treatment includes hydroxocobalamin, which turns skin/urine/plasma red.
54
What is the **incubation time** for **COVID-19**?
4-5 days ## Footnote The range can extend to 14 days, necessitating a 2-week quarantine for high-risk exposure.
55
What is the incubation period for **EBV**?
4-8 weeks ## Footnote This virus is associated with various diseases, including mononucleosis. and can cause Orchitis
56
What is **GEP** (Acute Generalized Exanthematous Pustulosis) primarily caused by?
90% due to medications ## Footnote Symptoms include pruritic, headache, and fever.
57
What is the **main cause** of **angioedema** associated with **aptopril**?
ACE inhibitor ## Footnote Angioedema is a serious side effect of ACE inhibitors.
58
What does **DRESS** stand for?
Drug Reaction with Eosinophilia and Systemic Symptoms ## Footnote This condition involves a severe drug reaction. The RegiSCAR scoring system assigns points to different clinical and laboratory findings to determine the likelihood of DRESS. Diagnosis is classified based on the total score: • <2: Excluded • 2-3: Possible • 4-5: Probable  • 6+: Definite
59
What are the two types of **Toxic Shock Syndrome**?
**Staphylococcal**● Toxic Shock Syndrome **Streptococcal**● Toxic Shock Syndrome ## Footnote Both involve toxin production.
60
What is the **mortality rate** for **Streptococcal Toxic Shock Syndrome**?
~ 50% ## Footnote This is significantly higher than the mortality rate for Staphylococcal Toxic Shock Syndrome—> 5%
61
True or false: **Staphylococcal Scalded Skin Syndrome** (SSSS) is associated with toxin production.
TRUE ## Footnote The syndrome is caused by Staphylococcus aureus exotoxins.
62
What are the **two types** of **Erythema Multiforme**?
* Minor * Major ## Footnote Major forms can lead to more severe conditions like Stevens-Johnson Syndrome.
63
What is the **Body Surface Area** involvement for **Stevens-Johnson Syndrome** (SJS)?
< 10% ## Footnote SJS is a serious condition that can progress to Toxic Epidermal Necrolysis (TEN).
64
What is the **most common etiology** for **Erythema Multiforme**?
HSV & mycoplasma pneumonia ## Footnote Other causes include sulfa drugs and seizure medications.
65
What is the **treatment** for **Dermatitis Herpetiformis**?
* Dapsone * Sulfapyridine ## Footnote The mechanism of action for these treatments is unknown.
66
What is the **dosing** for **IV Albumin** in **paracentesis**?
25% solution, 8 g/liter of ascites removed ## Footnote For example, if 5L is taken off, then 5x8 = 40 grams of 25% albumin.
67
What is the **causative agent** of **Tinea vesicolor**?
Malassezia furfur ## Footnote This yeast condition worsens with hot and sweaty weather.
68
What is the **treatment** for **Leprosy**?
* Dapsone * Rifampin ## Footnote Leprosy presents with anesthetic lesions and disfiguring nodules. mycoplasma lepre
69
What is the causative organism for **Erythrasma**?
Corynebacterium spp ## Footnote Erythrasma presents as brown, scaly skin patches, particularly in skin folds.
70
What color does the **WOODS lamp** show for Erythrasma?
RED ## Footnote This is a diagnostic feature for identifying Erythrasma.
71
What is the treatment for **Erythrasma**?
erythromycin ## Footnote Erythromycin is an antibiotic used to treat this skin condition.
72
List the **side effects** of **Amlodipine**.
* edema 5% * Erythema multiforme * Hepatitis * AMI ## Footnote These side effects can occur with the use of Amlodipine.
73
True or false: **Cocaine, Meth, and PCP** can cause persistent psychosis for several weeks after cessation.
TRUE ## Footnote This is a significant concern for users of these substances.
74
What symptoms are associated with **Cannabis-induced psychotic disorder**?
* Severe anxiety * Emotional lability * **Persecutory** delusions ## Footnote Symptoms can include feelings of being pursued or threatened.
75
What is **Reactive Arthritis** also known as?
Reiter’s Syndrome ## Footnote It is an autoimmune condition characterized by: **conjunctivitis** **urethritis** **arthritis**
76
What are the **key features** of **Reactive Arthritis**?
* Asymmetric arthritis * SeroNEGATIVE * Weight loading joints: knees, ankles, heels, SI joint, ischial tuberosity, ischial crest ## Footnote It usually occurs 2-6 weeks after urethritis or dysentery.
77
What infections can lead to **Reactive Arthritis**?
**GI illness** AND **Std** * Campylobacter * Salmonella * Shigella * Yersinia ## Footnote These pathogens are associated with diarrhea that can trigger the condition.
78
What is the treatment for **Reactive Arthritis**?
NSAID ## Footnote Nonsteroidal anti-inflammatory drugs are commonly used to manage symptoms.
79
What type of trauma is associated with **mass casualty** events?
BLAST TRAUMA ## Footnote High air-content organ systems are most at risk in such scenarios.
80
What are the most commonly injured organs in **blast trauma**?
* Tympanic membrane * Lung * Bowel ## Footnote These organs are particularly vulnerable due to their structure.
81
What percentage of **blast injuries** will have **T.M. rupture**?
95% ## Footnote More than 5% of T.M. ruptures may require surgical repair.
82
Which GI areas have the highest risk of perforation in **blast trauma**?
* Colon * Ileocecal junction ## Footnote These areas are particularly susceptible to injury.
83
What does **ABI** stand for in trauma assessment?
Ankle/Brachial Index ## Footnote It is calculated using doppler systolic blood pressure measurements.
84
What ABI value rules out **popliteal injury** with 99% NPV?
> 0.9 ## Footnote An ABI less than 0.9 in trauma indicates a need for further imaging however, 10% of severe popliteal artery injury will have normal DP and posterior tibial artery pulses  .
85
True or false: Normal pedal pulses may be present in nearly 10% of patients with an injury to the **popliteal artery**.
TRUE ## Footnote This can occur even with significant injuries.
86
What type of tourniquets are better for reducing pain and nerve damage?
WIDER tourniquets ## Footnote They are preferred over narrow ones for these reasons.
87
What is always fractured in any **Le Fort fracture**?
Pterygoid plate ## Footnote This is a key feature of all types of Le Fort fractures.
88
What are the types of **Le Fort fractures**?
* Le Fort I: pterygoid(hard palate) * Le Fort II: pterygoid(hard palate), orbital floor * Le Fort III: pterygoid(hard palate), orbital floor, zygoma * Le Fort IV: pterygoid(hard palate), orbital floor, zygoma, frontal bone ## Footnote Each type involves different structures of the facial skeleton.
89
What causes most delayed deaths in **hangings**?
●● **post obstructive pulmonary edema** ## Footnote post obstructive pulmonary edema can develop from significant negative intrapleural pressures.
90
What percentage of near-death hangings have **laryngeal injuries**?
50% ## Footnote These injuries can include thyroid cartilage or hyoid fractures.
91
What is the **first sensation** to go in compartment syndrome?
**temperature sensation** ## Footnote Compartment syndrome is suggested when the delta pressure (diastolic pressure minus compartment pressure) is less than 30 mm Hg. Most common method is ΔP: • Diastolic BP – compartment P • ΔP<30 is suspicious for ACS Keep limb at level of heart (avoid extreme elevation) • Oxygen saturation to improve availability to muscle • Correct systemic hypotension
92
In compartment syndrome, rarely does one lose **pulses** unless the compartment pressure is greater than the __________.
systolic blood pressure ## Footnote This indicates severe compartment syndrome.
93
List the symptoms of **necrotizing external otitis**.
* FEVER * SEVERE ear PAIN * NECK PAIN ## Footnote These symptoms indicate a serious condition requiring immediate medical attention.
94
What is the treatment for a **chalazion**?
Warm Compress and NO abx ## Footnote A chalazion is not very painful and is caused by a blocked meibomian duct.
95
What is the treatment for a **hordeolum**? hordeolum = stye
Warm Compress and NO abx ## Footnote A hordeolum is very painful and can be internal or external (stye). Search Assist A hordeolum, commonly known as a stye, is an infection of an oil gland at the edge of the eyelid, typically caused by bacteria. It appears as a painful, red bump and can be treated with warm compresses and, if necessary, antibiotic ointments.
96
Children with **lead encephalopathy** should be treated with combination therapy with __________ and __________.
calcium disodium EDTA and BAL (British anti-Lewisite) ## Footnote This treatment is crucial for managing lead poisoning.
97
What is the toxic level of lead in children that requires treatment?
> 5 mcg/dL ## Footnote Levels above this indicate potential lead poisoning.
98
What are the treatment options for lead poisoning in children?
* ADMISSION for level > 70 * ADMISSION for any symptoms with any level * HOME for asymptomatic AND levels 5-44 (remove Lead) * HOME for asymptomatic AND levels 45-69 (PO chelation) ## Footnote Treatment varies based on symptoms and lead levels.
99
For COVID-19, symptomatic patients can be released from isolation after how many days of improvement without fever?
10 days ## Footnote Asymptomatic individuals need 7 days of asymptomatic isolation.
100
What are the first-line treatments for **adult status epilepticus**?
* benzo’s * Fosphenytoin/Keppra/Valproate **KEPPRA max 60mg/kg with MAX 4.5 grams** * Phenobarbital ## Footnote These medications are critical in managing seizures.
101
Application of an **ice bag** should improve ptosis in patients with __________.
**myasthenia gravis** ## Footnote This is a common symptom in myasthenia gravis.
102
What are the potential effects of **hemodialysis**?
* transient hypotension (50%) * transient thrombocytopenia ## Footnote If bleeding occurs, DDAVP (desmopressin) can increase platelets.
103
What is the **most sensitive finding** for carpal tunnel syndrome?
need to double check Thenar eminence weakness ## Footnote Other findings include index finger pad sensory changes and Durkan’s test. 1. The patient's wrist is often held in a slightly flexed position. 2. The examiner uses their thumb(s) to apply firm pressure directly over the carpal tunnel (the area where the median nerve passes through the wrist).  3. The pressure is typically held for up to 30 seconds.
104
If a child is less than 1 month old with RSV bronchiolitis, what should be done?
admit for apnea observation ## Footnote This is crucial for monitoring potential complications.
105
What is the cyanosis threshold for **methemoglobinemia**?
≥ 5 grams/dl deoxygenated hgb ## Footnote This condition can cause a chocolate brown appearance when levels exceed 20%.
106
What causes **methemoglobinemia** in teething children?
benzocaine ## Footnote Normal range for methemoglobinemia is 1-2%.
107
How can you differentiate **congenital heart defect** from methemoglobinemia?
need to double check ABG before and after 100% oxygen ## Footnote CHD will show a low O2 sat and low PO2.
108
What is the treatment for symptomatic methemoglobinemia at 10%?
Methylene Blue ## Footnote This is the treatment for symptomatic cases.
109
What is the effect of **sulfhemoglobinemia**?
Central Cyanosis ## Footnote It can be caused by industrial chemicals and certain medications. Medications: This is the most common cause. Culprit drugs often include:  • Phenazopyridine (a urinary tract analgesic, sometimes misused)  • Sulfonamides (a class of antibiotics)  • Dapsone  • Metoclopramide Standard pulse ox tends to report falsely low value ABG, Co-oximetry Dark greenish-black blood Management Supportive care Severe toxicity may require exchange transfusion or PRBC transfusion Methylene blue does not reduce sulfhemoglobin levels
110
Define a **simple febrile seizure**.
< 15 mins, generalized, ONE seizure in 24h ## Footnote This is a common condition in children aged 6 months to 5 years.
111
Define a **complex febrile seizure**.
> 15 mins, focal, 2 or more episodes, age < 6 months or age > 5 yrs ## Footnote These seizures require further evaluation.
112
What is the treatment for **cerebral venous thrombosis (CVT)**?
heparin or lovenox ## Footnote This is recommended even if it causes ICH.
113
What is recommended for **high-risk** CVA/TIA patients?
asa and plavix ## Footnote This is based on the CHANCE and POINT trials. CHANCE Among patients with TIA or minor stroke who can be treated within 24 hours after the onset of symptoms, the combination of clopidogrel and aspirin is superior to aspirin alone for reducing the risk of stroke in the first 90 days and does not increase the risk of hemorrhage. POINT The primary goal of the POINT trial was to determine if initiating clopidogrel plus aspirin within 12 hours of a minor ischemic stroke (NIHSS score =< 3) or a high-risk TIA (ABCD2 score 4+) was more effective in preventing major ischemic events at 90 days than aspirin alone. j
114
What is a sign of a **pontine stroke**?
PIN POINT PUPILS ## Footnote This is a classic finding in pontine strokes.
115
What is a characteristic of a **locked-in stroke**?
intact eye blinking & vertical eye movement ## Footnote This condition results from a brainstem stroke.
116
What are symptoms of **posterior strokes**?
* vomiting * intractable hiccups * direction-changing nystagmus ## Footnote These symptoms can indicate a brainstem stroke.
117
What are the symptoms of a **Middle Cerebral Artery Stroke**?
* eyes deviate towards the lesion * hemianopsia (ipsilateral) * FACE and UPPER extremity weakness > lower extremity weakness * extremity weakness/sensory loss * aphasia ## Footnote These symptoms help in diagnosing the type of stroke.
118
What are the symptoms of an **Anterior Cerebral Artery Stroke**?
* lack of judgment * no insight into their condition * reappearance of primitive reflexes * LOWER extremity weakness > upper extremity weakness ## Footnote These symptoms are indicative of this type of stroke.
119
What does **NIHSS** stand for?
National Institutes of Health Stroke Scale ## Footnote A tool used to measure the severity of a stroke.
120
What is the **Modified Rankin Scale** (mRS) score for **no symptoms/disability**?
0 ## Footnote The mRS is used to measure the degree of disability or dependence in daily activities.
121
What NIHSS score range indicates **mild** stroke?
0-5 ## Footnote Mild strokes are characterized by no significant symptoms or disability.
122
What NIHSS score range indicates **moderate** stroke?
6-25 ## Footnote Moderate strokes may present with mild symptoms but no disability.
123
What NIHSS score indicates **severe** stroke?
26+ ## Footnote Severe strokes can result in significant disability.
124
What is the **time frame** for administering IV tPA for mild strokes with disabling symptoms?
0-3 hrs ## Footnote IV tPA is indicated for mild strokes with disabling symptoms.
125
What is the **blood pressure range** for patients not receiving tPA?
< 220/120 ## Footnote This is the acceptable BP range when not administering tPA.
126
What is the **blood pressure range** for patients receiving tPA?
< 185/110 ## Footnote Blood pressure must be controlled when administering tPA.
127
True or false: **AGE** is a contraindication to tPA.
FALSE ## Footnote Age is not a contraindication for administering tPA.
128
What are the **inclusion criteria** for unclear time of onset according to the 2019 guidelines?
* Independent at baseline (mRs 0-1) * Stroke is disabling * NIH 6-25 for thrombolysis * NIH 11+ for thrombectomy ## Footnote These criteria help determine eligibility for treatment in unclear onset strokes.
129
What imaging findings are required for administering tPA within 4.5 hours of stroke recognition?
* MRI with diffusion positive * FLAIR negative ## Footnote These findings indicate that the stroke is less than 4.5 hours old.
130
What is a **contraindication** to tPA?
* Ischemic stroke ≤ 3 months * Severe head trauma ≤ 3 months * Brain surgery ≤ 3 months * INR 1.8+ * Platelets < 100,000 * Glucose < 50 mg/dL * Stroke involving > 1/3 of MCA territory ## Footnote These conditions disqualify patients from receiving tPA.
131
What is the treatment for **stingray envenomation**?
HOT water soak ## Footnote Stingray venom is heat labile, so hot water helps alleviate pain.
132
What does **Ghon complex** represent in TB?
Healed calcified lung lesion ## Footnote It indicates a prior infection that has healed.
133
What is the **first-line treatment** for **von Willebrand Disease**?
Factor VIII ## Footnote Factor VIII contains extra von Willebrand factor (vWF) necessary for clotting.
134
What is the **positive Pathergy test** associated with?
* Behcet Syndrome * Pyoderma gangrenosum ## Footnote A positive test indicates active disease in these conditions.
135
What is the **treatment** for **organophosphate poisoning**?
atropine AND Pralidoxime * Muscarinic symptoms: SLUDGE → atropine * Nicotinic symptoms: paralysis → pralidoxime (2-PAM) reactivating the acetylcholinesterase enzyme by stripping the organophosphate molecule off the enzym ## Footnote Organophosphate poisoning affects both muscarinic and nicotinic receptors.
136
What is the **sensitivity** and **specificity** of the **ICE test** for Myasthenia Gravis?
* Sensitivity: 77% * Specificity: 98% ## Footnote The ICE test involves applying an ice pack to the eye to improve symptoms.
137
What is the **treatment** for **testicle trauma** if the tunica albuginea is not ruptured?
Conservative, nonsurgical treatment ## Footnote This approach is appropriate if there is no rupture.
138
What is the **treatment** for severe poisonings from **natural gas** infused with hydrogen sulfide (H2S)?
Hydroxocobalamin ## Footnote Hydroxocobalamin is used for severe H2S poisoning. H2S acts similarly to cyanide by inhibiting cellular respiration in the mitochondria. binds directly to the sulfide molecule, forming a stable, non-toxic compound that is excreted
139
What are the **diagnostic ECG criteria** for STEMI?
Two contiguous leads with ST-segment elevation of: * More than **2 mm** in leads V2 and V3 * More than 1 mm in all other leads ## Footnote These criteria help identify ST-Elevation Myocardial Infarction.
140
Which cervical vertebrae are most likely to have **unilateral facet dislocation**?
C5-C6 (most frequently reported) C3-C7 ## Footnote This occurs due to flexion/rotation of the neck and is unusually stable.
141
The **thoracolumbar spine** is most likely to have what type of dislocation?
Bilateral facet dislocation ## Footnote This type of dislocation is considered unstable.
142
What test is ordered to see if clear nasal fluid is **CSF**?
Beta-2 transferrin ## Footnote This test helps confirm the presence of cerebrospinal fluid.
143
What is the **Monteggia fracture**?
Proximal ulna fracture + radial head dislocation ## Footnote It requires immediate surgery for open reduction and internal fixation.
144
What is the **Galeazzi fracture**?
Distal radial fracture + distal radioulnar joint dislocation ## Footnote It may involve uncommon nerve injuries affecting radial/median nerves.
145
In **HSV keratitis**, if any lesion on eyelid or lips is present, what must be used?
The management involves a dual approach: 1. Topical Antiviral (For the Keratitis): • Ganciclovir 0.15% ophthalmic gel (less toxic to the cornea 2. PO antiviral PO antivirals ## Footnote Types include: * Epithelial type: more common, dendrites * Disciform type: deeper, disc-shaped areas of corneal edema.
146
What are the criteria for **salicylate/aspirin toxicity** requiring dialysis?
* Non cardiogenic pulmonary edema * Level > 100 mg/dL * AMS * pH < 7.2 ## Footnote Activated charcoal should be given within 2 hours of ingestion.
147
What are the common pathogens in **Otitis Externa**?
* Pseudomonas * Staph aureus ## Footnote Malignant Otitis Externa is a risk for DM and immunocompromised patients.
148
What is the most common complication of **Malignant Otitis Externa**?
CN 7 paralysis ## Footnote Treatment includes ceftazidime 50mg/kg IV q 8hrs to cover Pseudomonas and additional antibiotics for Staph aureus.
149
What is the PMN count that indicates **Spontaneous Bacterial Peritonitis (SBP)**?
PMN > 250 cells/mm3 ## Footnote Treatment involves 3rd generation cephalosporin.
150
What anatomical feature indicates the complexity of a **rectal abscess**?
Fluctuance above the dentate line ## Footnote An abscess below the dentate line may be treated in the emergency department with incision and drainage.
151
What causes a **lung abscess**?
Aspiration of anaerobic oropharyngeal bacteria ## Footnote This condition often requires specific antibiotic treatment.
152
What is the most common cause of **lung empyema**?
Strep pneumoniae ## Footnote Empyema is a collection of pus in the pleural cavity.
153
What are **Light’s criteria** for determining exudative pulmonary effusion?
Exudative if any of the following are met: * PF total protein/ST total protein > 0.5 * PF LDH/SLDH > 0.6 * PF LDH > ⅔ (LDH ULN) ## Footnote These criteria help differentiate between transudative and exudative effusions.
154
What are the **kinetics of ethanol metabolism**?
* First-order kinetics: fixed percentage per hour for low concentrations * Zero-order kinetics: fixed amount per hour for high concentrations ## Footnote First-order is more common in non-tolerant individuals.
155
What is **MDMA** also known as?
Ecstasy Molly ## Footnote It is a sympathomimetic that **increases vasopressin** release, leading to hyponatremia. 3,4-Methylenedioxy**methamphetamine**
156
What is the street name for **Rohypnol**?
Roofie ## Footnote Rohypnol is flunitrazepam, a sedative.
157
What is the first-line treatment for **stable VT**?
Amiodarone ## Footnote It can be used in AMI or severe LV dysfunction. Avoid procainamide/sotalol in prolonged QT interval.
158
What percentage of **Hirschsprung Disease** cases are associated with Down’s syndrome?
10% ## Footnote Hirschsprung Disease is a congenital condition affecting the large intestine.
159
What is **Fetor Hepaticus**?
Musty breath due to liver failure ## Footnote This symptom is indicative of severe liver dysfunction.
160
What is the characteristic breath odor in **Phenylketonuria (PKU)**?
Musty breath ## Footnote PKU is a metabolic disorder caused by a deficiency of phenylalanine hydroxylase.
161
What is a notable symptom of **Cystic Fibrosis**?
Salty skin ## Footnote This condition affects the respiratory and digestive systems.
162
What are some differential diagnoses for **no poop in 48 hours of birth**?
* Hypothyroidism * Hypokalemia * Hypercalcemia * CHF * Cystic fibrosis * Hirschsprung disease * Botulism * Paternal narcotics * Meconium plug syndrome * Anal stenosis/atresia ## Footnote These conditions can lead to delayed meconium passage.
163
Name some **encapsulated bacteria**.
eNCaPSS * Strep pneumoniae * Neisseria meningitidis * Haemophilus influenzae * Klebsiella pneumoniae * Salmonella typhi * Cryptococcus neoformans * Pseudomonas aeruginosa ## Footnote Encapsulated bacteria are often associated with increased virulence.
164
Why does **LACTULOSE** work for hepatic encephalopathy?
* Decreases GI pH and traps ammonia in stool * Hyperosmolar stool oftener * Stimulates bacteria to break down ammonia ## Footnote LACTULOSE helps reduce ammonia levels in the body, which is crucial for patients with hepatic encephalopathy.
165
What indicates an **AMI** in posterior leads?
**0.5mm** elevation in ANY of the posterior leads: V7, V8, V9 ## Footnote Posterior leads are important for diagnosing posterior myocardial infarctions.
166
True or false: **Video and fiberoptic laryngoscopy** are relatively contraindicated if the airway contains blood or vomit.
TRUE ## Footnote This is due to the risk of further airway obstruction or aspiration.
167
If a **nasal foreign body** is a button battery, what should NOT be used?
Vasoconstrictors ## Footnote Using vasoconstrictors can lead to alkaline necrosis.
168
Name the **high-risk animals** for rabies in the United States.
* Bats * Foxes * Raccoons * Skunks ## Footnote These animals are commonly associated with rabies transmission.
169
What is the **best test** to detect Giardia?
Stool Antigen ## Footnote This test is particularly relevant for individuals in daycares or during camping.
170
What are the **early findings** of Normal Pressure Hydrocephalus?
* Ataxia * Urinary incontinence ## Footnote Normal Pressure Hydrocephalus can develop in individuals under 60 years old.
171
What can result from **CSF shunt overdrainage**?
Subdural hematoma from tearing of the bridging veins ## Footnote This complication can occur due to rapid changes in intracranial pressure.
172
What is the **emergency contraception** option if 3+ days have passed?
Copper IUD ## Footnote The Copper IUD is an effective emergency contraceptive method.
173
What type of stone is referred to as **Staghorn calculi**?
Struvite stone (Mg-ammonium-phosphate) ## Footnote These stones are often associated with urinary tract infections.
174
What type of crystals are associated with **GOUT**?
Negative Birefringent crystals = MONOsodium urate crystals ## Footnote GOUT is characterized by the accumulation of uric acid crystals in joints.
175
What is a key feature of **Brugada Syndrome**?
Abnormal Na channels ## Footnote This condition can lead to polymorphic ventricular tachycardia.
176
What viral illness is characterized by **high fever** that breaks into a rash in children?
Roseola infantum: Human Herpes 6 virus ## Footnote This condition typically affects children aged 6 months to 1 year.
177
What are the **3 C's** associated with **Rubeola (Measles)**?
* Cough * Coryza * Conjunctivitis ## Footnote Measles is also characterized by Koplik spots.
178
What are the symptoms of **Rubella (German measles)**?
* Post auricular and posterior cervical lymphadenopathy * Polyarticular joint pain * **Soft palate petechiae** ## Footnote Rubella can have congenital effects including mental impairment and cataracts. Quick Answer: Measles (rubeola) and German measles (rubella) are different viral infections. Measles is more severe, highly contagious, and can cause life-threatening complications, while German measles is usually milder but dangerous in pregnancy because it can cause birth defects in babies cleveland... +3. --- 🌟 Key Differences Between Measles and German Measles Feature Measles (Rubeola) German Measles (Rubella) Virus Caused by the measles virus (Morbillivirus) Caused by the rubella virus (RuV) Severity Severe illness; can lead to pneumonia, encephalitis, and death Usually mild; often resolves in a few days Contagiousness Extremely contagious (90% of unvaccinated people exposed will get it) mayoclini... +2 Symptoms High fever, cough, runny nose, red eyes, Koplik’s spots in mouth, rash spreading from face downward cleveland... +4 Duration Illness lasts 10–14 days Rash and symptoms last 1–5 days (“three-day measles”) mayoclinic.org Complications Can cause blindness, brain swelling, immune suppression, pregnancy complications cleveland... +3 Prevention MMR or MMRV vaccine (two doses give ~97% lifelong protection) cdc.gov +4 --- 🧾 Important Notes • Measles is more dangerous overall: It can hospitalize 2 out of 5 patients and cause long-term immune damage clevelandcli.... • Rubella is mild in most people but severe in pregnancy: Infection in the first trimester can cause miscarriage or congenital rubella syndrome in up to 85% of cases cleveland... +1. • Vaccination is the best protection: The MMR vaccine protects against both measles and rubella, and is part of routine childhood immunization worldwide cdc.gov +2. So, while both illnesses cause rashes and are prevented by the same vaccine, measles is the more severe disease, and rubella is especially feared because of its effects on unborn babies. ---
179
What is the characteristic rash of **Pityriasis rosea**?
Christmas tree pattern, herald lesion ## Footnote This condition is self-limiting and often itchy.
180
What is the **most common device complication** of a **Left Ventricular Assist Device (LVAD)**?
Suction event ## Footnote This occurs when the inflow cannula gets 'sucked down' against the LV due to negative pressures.
181
What is the **most common non-device complication** of LVAD?
Bleeding due to anticoagulation and mechanical destruction of vWF ## Footnote Treatment may involve desmopressin to increase vWF levels.
182
What should be done if a patient with an LVAD has a MAP of less than 50 mm Hg?
Chest compressions should be performed ## Footnote This is part of the resuscitation protocol for LVAD patients.
183
What type of fracture is considered **unstable** in a Motor Vehicle Accident (MVA)?
Burst fracture ## Footnote Burst fractures can be misdiagnosed as compression fractures.
184
What indicates the need for a **surgical thoracotomy**?
> 1,500 cc initially or > 200cc/hr ## Footnote This is relevant for chest tube thoracostomy management.
185
What is **Pseudocyanosis**?
Abnormal skin pigmentation that can mimic cyanosis ## Footnote Heavy metals use and Hemochromatosis can cause slate gray or brownish discoloration in sun-exposed skin.
186
What distinguishes **Pseudocyanosis** from true cyanosis?
No blanching of affected areas ## Footnote This is a key indicator to differentiate between the two conditions.
187
What is the effect of **Class III antiarrhythmics** on action potential duration?
Prolong normal tissue APD and refractory period > injured tissue APD and refractory period ## Footnote This is important for understanding the pharmacodynamics of these medications.
188
What are the side effects of **Propranolol**?
* Lipophilic neurologic side effects (AMS, coma, seizures) * Bradycardia * Hypotension * QRS widening ## Footnote Propranolol is a beta-blocker affecting both B1 and B2 receptors.
189
What is the significance of **Sotalol** in treatment?
B1/B2 blocker (class II), K blocker (class III) ## Footnote Sotalol requires 24-hour observation due to its long half-life.
190
What medication worsens **AMS/asterixis** in liver failure?
Benzodiazepines ## Footnote Lorazepam is preferred due to its phase 2 metabolism.
191
What is the most common cause of **esophageal perforation**?
Iatrogenic (upper endoscopy) ## Footnote Symptoms can mimic aortic dissection, including neck/chest/abdominal pain.
192
What are the symptoms of **pyloric stenosis**?
* Non-bilious vomiting at the end of feeding * Hungry after vomiting * Male to female ratio 4:1 * Metabolic alkalosis with hypoCl, hypoK ## Footnote Typically occurs in infants aged 2-6 weeks.
193
What does the **Corkscrew Sign** indicate on X-ray?
Gut malrotation ## Footnote This sign is associated with abnormal intestinal positioning.
194
What does the **Double Bubble sign** indicate?
Duodenal atresia ## Footnote Characterized by a dilated stomach and narrow pyloric area.
195
What does the **Target Sign** indicate?
Intussusception ## Footnote Rarely found in infants under 5 months old.
196
What is the typical presentation of **necrotizing enterocolitis**?
* Usually occurs in neonates < 3 days old * 90% in premature neonates * Blood stools * XR shows pneumatosis intestinalis ## Footnote This condition is a serious gastrointestinal emergency.
197
What is the treatment for **pneumothorax (PTX)** ≤ 15%?
Oxygen and repeat X-ray ## Footnote This approach helps in monitoring the condition.
198
What is the first step in treating **acute angle-closure glaucoma**?
Decrease IOP ## Footnote Medications include timolol, brimonidine, and acetazolamide.
199
What is the role of **pilocarpine** in glaucoma treatment?
Maintain IOP normalcy by promoting drainage ## Footnote It works by constricting the pupil, pulling the iris away.
200
What is the highest risk procedure for **aerosolization** in COVID patients?
Intubation ## Footnote Heated high flow may reduce aerosolization.
201
What is the diagnostic method for **malaria**?
* Microscopic thick blood smears * Thin blood smears ## Footnote Three negative smears within 12 hours are needed for diagnosis.
202
What are the symptoms of **Q Fever**?
Fever, fatigue, loss of appetite ## Footnote Treatment includes doxycycline for 2 weeks.
203
What are the risk factors for **Posterior Reversible Encephalopathy Syndrome (PRES)**?
* Immunosuppressive medications * Autoimmune conditions * Hypertension * Pregnancy ## Footnote  risk factors P: pregnancy R: rheumatologic conditions E: accelerated hypertension S: sepsis MRI is the diagnostic test of choice, and findings consistent with PRES include vasogenic edema, often found in the parieto-occipital locations bilaterally. If MRI is unavailable, perform a computed tomography (CT) scan of the brain, which can also show vasogenic edema. These factors can contribute to the development of PRES. C - Cephalgia (Headache): Usually severe and constant; it often comes on rapidly. • C - Convulsions (Seizures): This is the most common symptom, occurring in about 70-80% of patients. • C - Confusion: Patients may be agitated, disoriented, or have difficulty focusing. In severe cases, it can progress to a coma. • V - Visual Disturbances: This ranges from blurred vision to hallucinations or cortical blindness (where the eyes work, but the brain cannot process the image).
204
What is the most common cause of **meningitis**?
Streptococcus pneumoniae ## Footnote Giving steroids can improve mortality with this pathogen.
205
What are the lab findings in **HELLP syndrome**?
* Normal fibrinogen/PT/PTT * Elevated AST > 70 U/L * Elevated TBili > 1.2 mg/dL * Decreased platelets < 100 ## Footnote Treatment is delivery if > 34 weeks pregnant.
206
What are the symptoms of **cholestasis of pregnancy**?
Very itchy, elevated LFTs ## Footnote No elevated BP or abnormal platelet levels.
207
What is the treatment for **eclampsia**?
Magnesium ## Footnote Calcium gluconate is used for magnesium toxicity.
208
What is the significance of **Rhogam** in pregnancy?
Given within 3 days of trauma to prevent Rh sensitization ## Footnote Dosage varies based on gestational age and amount of fetal blood.
209
What is the most sensitive test for **placental abruption**?
Cardiotocodynamometry ## Footnote This test identifies uterine irritability and contractions.
210
What is the treatment for **trauma in pregnancy**?
Monitor for placental abruption and administer Rhogam if indicated ## Footnote Important to rule out fetal blood exposure.
211
What is the first symptom of **HAPE**?
Decreased exercise performance ## Footnote This condition is caused by hypoxia leading to pulmonary hypertension.
212
What is the treatment for **botulism**?
Botulism immune globulin 0.5mL/kg/hr ## Footnote Symptoms include abdominal cramping and generalized weakness.
213
What is the effect of **tetanus toxin**?
Irreversibly binds to anterior horn cell receptors ## Footnote Clinical tetanus lasts 4-6 weeks.
214
What is the treatment for **traveler’s diarrhea** without fever?
Reassurance and symptomatic therapy ## Footnote Antibiotics are only indicated if fever is present.
215
What does **Yersinia enterocolitica** cause?
Ileoceitis mimicking appendicitis ## Footnote Typically self-limiting illness associated with undercooked pork.
216
What is the characteristic finding in **toxic megacolon**?
Loss of haustra ## Footnote Thumbprinting may also be observed on imaging.
217
What are the characteristics of **Fibrocystic breast changes**?
* Nodular * Mobile * Smooth ## Footnote Nipple retraction may indicate cancer.
218
At what age can a **Branchial cleft cyst** appear?
≤ 5 yo ## Footnote The 2nd cleft is the most common and treatment involves outpatient excision.
219
In **appropriate respiratory compensation**, the second two numbers of the pH roughly equate to the **Pco2**. What is the example given?
pH 7.23, Pco2 23 ## Footnote This indicates a relationship between pH and carbon dioxide levels.
220
True or false: **COMA + Respiratory Alkalosis** can indicate toxic alcohols or ethanol.
TRUE ## Footnote It may also be associated with hypothermia.
221
What is the #1 cause of **Nephrotic Syndrome**?
Minimal change (no hematuria) ## Footnote The liver compensates for albumin loss by increasing protein synthesis, leading to hyperlipidemia and clotting factors.
222
What are the two types of **Hordeolum (Stye)**?
* External: infection of hair follicles of the eyelashes * Internal: infection of meibomian glands ## Footnote A **Chalazion** is a non-painful internal hordeolum due to granuloma formation.
223
What are the types of **Peripheral Vertigo/Dizziness**?
* Meniere’s disease * Acoustic neuroma * BPPV * Labyrinthitis * Vestibular Neuritis ## Footnote
224
What is the treatment for **Meniere’s disease**?
Meclizine ## Footnote It is used to manage symptoms of vertigo and dizziness.
225
What is the difference between **Labyrinthitis** and **Vestibular Neuritis**?
* Labyrinthitis: hearing loss and tinnitus * Vestibular Neuritis: normal hearing ## Footnote Labyrinthitis often follows an acute otitis media (AOM).
226
What is the significance of **Wallenberg (Lateral Medullary Syndrome)**?
Intact hearing despite symptoms similar to Acoustic Neuroma ## Footnote It involves PICA (Posterior Inferior Cerebellar Artery) and presents with various sensory deficits.
227
What are the **Otic Toxic Medications** that can affect hearing?
* Furosemide * ASA * Azithromycin * Aminoglycosides (tobramycin, gentamicin) * Phosphodiesterase inhibitors (cilostazol, sildenafil, dipyridamole, caffeine) ## Footnote These medications can lead to hearing toxicity.
228
What does a **Weber Test** indicate if sound is perceived in the middle?
Normal hearing bilaterally or bilateral sensorineural hearing loss ## Footnote Localizing to one side indicates either ipsilateral conductive hearing loss or contralateral sensorineural hearing loss.
229
What is the triad of **Wegner glomerulonephritis**?
* Sinusitis * Pulmonary infiltrates * Glomerulonephritis ## Footnote This condition is associated with vasculitis.
230
What is the **Rinne Test** used for?
To assess air conduction vs bone conduction hearing ## Footnote A normal Rinne test (AC>BC) is termed 'Rinne positive'.
231
What are the symptoms of **Conversion Disorder**?
* 1+ motor or sensory symptoms * Symptoms are unconscious ## Footnote Do NOT use inconsistent effort or la belle indifference as diagnostic criteria.
232
What is the treatment for **Rocky Mountain Spotted Fever (RMSF)**?
Doxycycline for 2-4 weeks ## Footnote Symptoms include flu-like illness and a characteristic rash.
233
What is the most common manifestation of **Lyme disease** in children?
Erythema migrans ## Footnote Treatment includes doxycycline, amoxicillin, or cefuroxime.
234
What is the primary symptom of **Babesiosis**?
Flu-like illness with hemolytic anemia ## Footnote It can occur in 40% of Lyme disease patients.
235
What is the most common zoonotic disease in the world?
Leptospirosis ## Footnote It is associated with water contact and can lead to multiorgan failure.
236
What are the common causes of **Food Poisoning/Diarrhea**?
* Staph aureus * Bacillus cereus * Clostridium perfringens * Salmonella typhimurium ## Footnote Each has distinct onset and symptoms.
237
What is the treatment for **fulminant C. diff colitis**?
Early subtotal colectomy ## Footnote It has an 80% mortality rate if not treated promptly.
238
What is the most common lab abnormality in **COVID-19**?
Lymphopenia (83%) ## Footnote This finding is significant in the diagnosis and management of the disease.
239
What are the symptoms of **Cluster Headaches**?
* Unilateral * Lacrimation * Conjunctival injection * Nasal congestion * Ptosis * Miosis ## Footnote They typically last less than 3 hours.
240
What is the most common type of **skin cancer**?
Basal Cell Carcinoma ## Footnote It is slow-growing and often appears as a 'rodent ulcer'.
241
What does **Seborrheic Keratosis** look like?
Waxy, stuck-on brown/black/tan growths ## Footnote It is a benign skin condition.
242
What is **Actinic Keratosis** considered?
Pre-cancer ## Footnote It presents as irregular, erythematous, scaly papules.
243
What is the significance of **neck zones in trauma**?
They help to categorize injuries and guide management ## Footnote Understanding these zones is crucial for trauma assessment.
244
What does **SCIWORA** stand for?
Spinal Cord Injury Without Radiographic Abnormality ## Footnote More common in younger than older children, with flexion and extension being the most common mechanism.
245
What can a **galea aponeurosis laceration** lead to?
* Loss of frontalis muscle function * Subgaleal hematoma ## Footnote This type of laceration is significant in forehead injuries.
246
What is the treatment for **Acute Radiation Proctocolitis**?
* Mild: steroid enema, fiber stool softeners * Decrease radiation dose ## Footnote 50% will develop this when receiving radiation to the pelvis.
247
What is **Cryptococcal meningitis** caused by?
Cryptococcus neoformans ## Footnote It is a fungal infection that occurs in 10% of AIDS patients and mimics viral meningitis.
248
What are the stages and initial treatments for **Lyme Disease**?
* Early: Erythema migrans - Oral antibiotics * Carditis - IV antibiotics * Isolated cranial nerve palsy - Oral antibiotics * Meningitis - Oral or IV antibiotics * Late: Acute arthritis - Oral antibiotics * Recurrent arthritis - Oral or IV antibiotics * Encephalitis - IV antibiotics ## Footnote Lyme disease has distinct stages with specific presentations and treatments.
249
What is **Scarlet Fever** characterized by?
* Active strep infection * Sandpaper rash * Strawberry tongue * Forchheimer spots * Pastia lines * Facial flushing with mouth pallor ## Footnote Patients can develop post-glomerulonephritis and rheumatic fever regardless of antibiotic treatment.
250
What are the **rashes that start on the face**?
* Scarlet Fever * Measles * German measles (Rubella) ## Footnote These conditions are notable for their facial rash presentation.
251
What is **Tumor Lysis Syndrome (TLS)** associated with?
* Hyperuricemia * Hypocalcemia * Elevated LDH * Hyperkalemia * Hyperphosphatemia ## Footnote TLS usually occurs within 5 days after chemotherapy or radiation.
252
What are the symptoms of **Multiple Myeloma (MM)**?
* Hyperuricemia * Hypercalcemia * Depression * Lethargy * Bones/stones/psychiatric overtones * Short QT interval ## Footnote MM affects calcium regulation and can lead to various complications.
253
What is the **treatment** for **Hyperviscosity Syndrome**?
* Plasmapheresis (if Ig mediated) * Leukapheresis (leukemia, polycythemia) ## Footnote Clinical manifestations include CHF, mucosal bleeding, and respiratory failure.
254
What is **Kawasaki Disease** characterized by?
* 5 days of fever * 4 out of 5 criteria: erythema of palms and soles, maculopapular rash, bilateral conjunctivitis, lip/oral redness, cervical lymphadenopathy ## Footnote 85% of cases occur in children aged 6 months to 5 years.
255
What is the difference between **Complete** and **Incomplete Kawasaki Disease Diagnosis**?
* Complete: 5 days of fever + 4 out of 5 criteria * Incomplete: 5 days of fever + 2 out of 5 criteria + CRP ≥ 3.0 mg/dl or ESR ≥ 40 mm/hr + 3+ lab findings ## Footnote Incomplete Kawasaki can present similarly to viral illness.
256
What is **Molluscum contagiosum** also known as?
Water warts ## Footnote This viral pox infection is contagious as long as there are warts and typically self-resolves within a year.
257
What are the characteristics of **Scabies mites** infestation?
* Itchy rash * Red papule with hemorrhagic crusts * Worse at night * Tunnel-like lines of skin eruptions ## Footnote Treatment includes Permethrin cream 5%.
258
What is the treatment for **Pubic lice (Phthirus pubis)**?
* Permethrin 5% topical * PO Ivermectin ## Footnote Effective treatment options for lice infestation.
259
What are the types of **Hypersensitivity Reactions**?
* Type I: Immediate, anaphylaxis * Type II: Antibody-related (Goodpasture syndrome) * Type III: Immune complex-mediated (Post streptococcal glomerulonephritis) * Type IV: Delayed, cell-mediated (Contact dermatitis) ## Footnote Each type has distinct mechanisms and examples.
260
What is the treatment for **Travelers Diarrhea** caused by **Entamoeba histolytica**?
Metronidazole ## Footnote Risk factors include travel to Taiwan/Japan, homosexual men, and immunocompromised states.
261
What is the most common cause of **pediatric ataxia**?
Acute Cerebellar Ataxia (ACA) ## Footnote It is often post-viral and characterized by a wide-based gait.
262
What is the treatment for **Guillain-Barre Syndrome (GBS)**?
* Plasmapheresis * IVIG ## Footnote Steroids are not recommended in the treatment of GBS.
263
What are the symptoms of **Cirrhosis**?
* Decrease Protein C and Antithrombin * Decrease clotting factors * Pro clotting and pro bleeding ## Footnote F VIII and von Willebrand Factor are synthesized by endothelial cells, not the liver.
264
What are the symptoms of **Vitamin B1 (Thiamine) deficiency**?
* Wet: tachycardia, peripheral edema * Dry: weakness, confusion, decreased tendon reflexes ## Footnote Wernicke encephalopathy and Korsakoff syndrome are forms of dry beriberi.
265
What is the quickest test for **DEMENTIA**?
Clock test ## Footnote Dementia diagnosis requires cognitive decline in at least one domain, slow onset, and gradual progression.
266
What are the four causes of **DELIRIUM**?
* Add medications * Withdrawal from medications * Dementia * Systemic illness ## Footnote Delirium can cause various types of hallucinations.
267
What is the treatment for **Tinea capitis**?
PO terbinafine x 4 weeks, PO griseofulvin 6 weeks ## Footnote This fungal infection affects hair shafts.
268
What is the characteristic of **Bed bugs (Cimex lectularius)** bites?
Pruritic bites ## Footnote They do not transmit diseases and do not infest skin.
269
What is the treatment for **Hemophilia A**?
Factor VIII 50 units ## Footnote 1U/kg increases Factor VIII level by 2%.
270
What is an **esophageal web**?
Congenital membrane allowing liquid but not solids to pass ## Footnote It can lead to neonatal GERD.
271
What is the treatment for **anal fissure**?
* Sitz baths * Lidocaine gel * Nifedipine gel ## Footnote These treatments help alleviate symptoms.
272
What is the characteristic of **Norwegian scabies**?
Crusted and hyperkeratotic plaques or nodules ## Footnote It occurs in immunosuppressed patients and looks like psoriasis.
273
What is the treatment for **Shingles (Herpes zoster)** affecting the nose?
* Eye steroid drops * PO valcyclovir/acyclovir ## Footnote Hutchinson sign indicates nasociliary branch involvement.
274
What is the primary cause of **Idiopathic Thrombocytopenia Purpura (ITP)**?
Virus leading to immune response and antibodies to platelets ## Footnote Primary ITP has a 90% recovery rate without treatment.
275
What is **TTP (Thrombotic Thrombocytopenic Purpura)** characterized by?
* Anemia (hemolytic) * Thrombocytopenia * AMS * Fever * Schistocytes on peripheral smear ## Footnote It involves antibodies to ADAMTS13.
276
What is the **treatment** for **Thrombotic Thrombocytopenic Purpura (TTP)**?
* Therapeutic plasma exchange * Steroids * Ø platelets ## Footnote TTP is characterized by anemia, thrombocytopenia, and neurological symptoms.
277
What are the **key features** of **Hemolytic Uremic Syndrome (HUS)**?
* Diarrhea * Anemia (hemolytic) * Acute renal failure (ARF) ## Footnote HUS is often associated with Shiga toxin from E. coli 0157:H7.
278
In **Addison Disease**, what are the **common electrolyte imbalances**?
* Hyponatremia * Hyperkalemia * Hypercalcemia ## Footnote Addison's disease results from primary adrenal insufficiency.
279
True or false: **Amiodarone thyrotoxicosis** type 1 is characterized by decreased blood flow on ultrasound.
FALSE ## Footnote Type 1 is an exacerbation of an underlying toxic goiter with increased blood flow.
280
What are the **symptoms** of **myxedema coma**?
* Nonpitting edema * Buildup of hyaluronic acid in tissues ## Footnote Myxedema coma is a severe form of hypothyroidism.
281
What is the **treatment** for **pheochromocytoma**?
* Phentolamine ## Footnote Avoid labetalol due to its stronger beta-blocking effects.
282
What are the **characteristics** of **Frontotemporal neurocognitive disorder**?
* Hyperorality * Wandering * Disinhibited behavior ## Footnote This disorder typically affects younger individuals under 65.
283
What is the **first-line treatment** for **hypercalcemia due to malignancy**?
* NS fluids * Bisphosphonates (e.g., zoledronic acid) * Calcitonin ## Footnote Bisphosphonates take 2 days to reach peak effect.
284
What is the **screening recommendation** for **abdominal aortic aneurysm (AAA)** in men aged 65 to 75 who have ever smoked?
One-time screening by ultrasonography ## Footnote This is a Grade B recommendation by the US Preventive Services Task Force.
285
What are the **symptoms** of **epiglottitis**?
* Laryngeal 'rock' sign * Hot potato voice * Better sitting up/tripod position ## Footnote Epiglottitis can lead to airway obstruction.
286
What is the **treatment** for **diphtheria**?
* Diphtheria antitoxin * Erythromycin ## Footnote Death can occur due to aspiration of the pseudomembrane.
287
What are the **common causes** of **unilateral red eye**?
* HSV * HZV * Acute angle glaucoma ## Footnote Unilateral red eye can indicate serious conditions.
288
What are the **characteristics** of **Vernal Conjunctivitis**?
* IgE type 1 hypersensitivity * Cobblestone papillae under upper lid * Stringy mucoid discharge ## Footnote This condition is common in children during summer months.
289
What is the **first-line treatment** for **bacterial tracheitis**?
* Intubation * Antibiotics ## Footnote Bacterial tracheitis often follows upper respiratory infections.
290
What are the **three groups** for **triage** in radiation exposure?
* Survival probable * Survival possible * Survival improbable ## Footnote This classification helps in managing patients after radiation exposure.
291
What is the **primary cause** of **splenic venous thrombosis**?
Chronic pancreatitis ## Footnote This condition can lead to left-sided portal hypertension.
292
What is the **definition** of **transferrin**?
Binds iron in the serum ## Footnote Transferrin is essential for iron transport in the blood.
293
What is the **treatment** for **thrombosed external hemorrhoids**?
* Excision if ≤ 720 * Topical lidocaine and Sitz bath if 720+ ## Footnote Excision will not improve pain for larger thrombosed hemorrhoids.
294
What is the **most common cancer** in individuals under 15 years old?
ALL (acute lymphocytic leukemia) ## Footnote This type of leukemia is characterized by the overproduction of immature lymphocytes.
295
In **sickle cell disease**, what is the treatment for **Acute Chest Syndrome**?
* IVF * Oxygen * Antibiotics * Pain medications * Blood transfusion/exchange transfusion ## Footnote Hydroxyurea is used prophylactically to prevent crises.
296
What are the **common bacteria** associated with **sickle cell disease** complications?
* Mycoplasma pneumonia * Chlamydia pneumoniae * Strep pneumonia * H. influenzae * N. meningitidis * Klebsiella pneumonia * E. coli * Salmonella ## Footnote These bacteria are particularly dangerous due to the compromised spleen function in sickle cell patients.
297
What is the **reticulocyte count** in an **aplastic crisis**?
Decreased ## Footnote This is often due to folate deficiency or a post-infectious process.
298
In **iron deficiency anemia**, what is the **serum ferritin** level?
Low ## Footnote Ferritin is a marker of stored iron in the body.
299
True or false: **Lead poisoning** can cause **microcytic anemia**.
TRUE ## Footnote Lead interferes with hemoglobin synthesis, leading to microcytic anemia.
300
What is the **TIBC** level in **anemia of chronic disease**?
Low ## Footnote TIBC (Total Iron Binding Capacity) reflects the body's iron availability.
301
What are the **characteristics** of **sideroblastic anemia**?
* Microcytic * Hypochromic ## Footnote This type of anemia is characterized by the presence of ringed sideroblasts in the bone marrow.
302
What is the **LDH** level in **hemolytic anemia**?
Increased ## Footnote LDH (Lactate Dehydrogenase) is released during the breakdown of red blood cells.
303
What is the **indirect bilirubin** level in **hemolytic anemia**?
Increased ## Footnote Indirect bilirubin is elevated due to increased breakdown of hemoglobin.
304
What is the **most common treatment** for **gonorrhea**?
Ceftriaxone 500mg IM x1 ## Footnote This treatment is effective for genital infections.
305
What is the **incubation period** for **chlamydia**?
1-3 weeks ## Footnote Many individuals are asymptomatic during this period.
306
What is the **treatment** for **primary syphilis**?
PCN G benzathine 2.4 million units IM x one ## Footnote Treatment should be administered within 24 hours to avoid Jarisch-Herxheimer reaction.
307
What are the **four stages** of **pericarditis**?
* PR depression with diffuse ST segment elevation * Normal ECG * Diffuse T wave inversion * Normal ECG or permanent T wave inversion ## Footnote The first stage is often associated with viral infections.
308
What is the **Hoffman Reflex** indicative of?
Cervical myelopathy ## Footnote A positive Hoffman reflex suggests a lesion above the origin of the brachial plexus.
309
What is the **treatment** for **HIV esophagitis** caused by **Candida**?
Fluconazole ## Footnote If treatment fails, consider CMV infection.
310
What is the **CD4 count** that indicates **AIDS**?
< 200 ## Footnote This count signifies severe immunosuppression.
311
What is the **first-line treatment** for **aortic dissection**?
Esmolol ## Footnote This medication helps control blood pressure and heart rate.
312
What is the **risk factor** for **aortic dissection** in individuals under 40?
Marfan syndrome ## Footnote Marfan syndrome is a connective tissue disorder that increases the risk of aortic dissection.
313
What is the **most common location** for an **aortoenteric fistula**?
Distal half of Duodenum ## Footnote This condition can lead to massive upper GI bleeding.
314
What is the **treatment** for **scabies**?
Permethrin cream 5% ## Footnote The cream should be washed off after 8 hours.
315
What is the **characteristic rash** of **HSV**?
Painless vesicular lesions ## Footnote HSV can transmit even without symptoms.
316
What is the **treatment** for **bacterial vaginosis**?
* Metronidazole 500mg bid x 7d * Vag metro gel 0.75% 5G x 5d * Vag clindamycin 2% cream QHS x 7d ## Footnote All symptomatic women should be treated.
317
What is the **treatment** for **chancroid**?
Ceftriaxone 500mg IM x1 ## Footnote This is effective for genital ulcers caused by Haemophilus ducreyi.
318
What is the **treatment** for **polymyalgia rheumatica**?
Corticosteroids ## Footnote This condition typically affects individuals over age 50.
319
What is the **risk factor** for **endometritis**?
* C-section * Retained products of conception * Premature rupture of membranes * Intrauterine monitoring device * Young maternal age * Frequent vaginal exams ## Footnote These factors increase the likelihood of developing endometritis.
320
What is the **treatment** for **alcoholic ketoacidosis**?
IV fluids and glucose ## Footnote This condition typically occurs after a binge drinking episode.
321
What is the **most common cause** of **myocarditis** worldwide?
Chagas disease (Trypanosoma cruzi) ## Footnote This parasitic infection is prevalent in Latin America.
322
What is the **treatment** for **acute graft rejection**?
Immunosuppressive therapy ## Footnote This is necessary to manage the cellular response.
323
What is the leading cause of **myocarditis** worldwide?
Chagas disease (Trypanosoma cruzi) ## Footnote Chagas disease is a significant concern in regions where it is endemic.
324
What are the components of **Beck’s Triad**?
* Hypotension * Muffled heart sounds * Jugular venous distension ## Footnote Beck's Triad is associated with cardiac tamponade.
325
What is **priapism**?
Painful erection lasting > 2 hours ## Footnote Untreated priapism can lead to 35% impotence due to fibrosis in the corpus cavernosum.
326
What are the two types of **priapism**?
* Low-Flow (ischemic) * High-Flow (non-ischemic) ## Footnote Low-Flow is painful and often associated with conditions like sickle cell disease, while High-Flow is non-painful and often due to trauma.
327
What does a **red flag** indicate at the beach?
Unsafe conditions, beach closed for swimming ## Footnote Beach flags communicate water safety conditions.
328
What is the **sensitivity** of Pulsus Paradoxus for Tamponade?
> 10 mm Hg has sensitivity of 82% ## Footnote Pulsus Paradoxus is a clinical sign observed in cardiac tamponade.
329
What is the **most common** cause of pediatric parotitis?
Mumps ## Footnote Mumps starts unilateral but can become bilateral in 70% of cases.
330
What is the **treatment** for acute necrotizing ulcerative gingivitis (ANUG)?
Dilute 3% hydrogen peroxide mouth rinses and PO antibiotics for 7-10 days ## Footnote ANUG is characterized by pain, ulcerated interdental papillae, and gingival bleeding.
331
What is the **most common** site for salivary gland stones (sialolithiasis)?
Submandibular gland (80%) ## Footnote The submandibular gland has the longest duct and lowest saliva flow, leading to stone formation.
332
What is the **diagnosis** for Pseudotumor Cerebri?
LP opening pressure ## Footnote Non-obese patients > 20 cmH20, obese patients > 25 cmH20.
333
What is the **first step** in rabies postexposure prophylaxis?
Wash wound with SOAP/H2O then clean with IODINE ## Footnote This is crucial to prevent rabies infection.
334
What is the **mortality rate** for pulmonary anthrax?
~100% mortality (even with treatment) ## Footnote Pulmonary anthrax is the most lethal form of anthrax.
335
What are the **Ottawa knee rules** for radiography necessity?
* Patient age > 55 years * Cannot transfer weight from one foot to the next * Cannot flex knee 90 degrees * Patellar tenderness without other bone tenderness * Tenderness in the fibular head ## Footnote These rules help determine the need for knee X-rays.
336
What is the **most serious** injury associated with posterior elbow dislocation?
Brachial artery injury (8%) ## Footnote This injury can lead to significant complications.
337
What is the **most common** type of rotator cuff tear?
Supraspinatus tear ## Footnote Pain is often worse at night and over the greater tuberosity.
338
What is the **treatment** for a Boxer's fracture?
Ulnar gutter splint in position of function ## Footnote This is for a 5th metacarpal fracture with ≤ 45˚ angulation.
339
What is the **characteristic** of a painless ulcer?
Syphilis ## Footnote This is the only ulcer that is typically painless.
340
What is the **treatment** for Legionnaires Disease?
Ciprofloxacin or doxycycline ## Footnote This disease is caused by Legionella pneumophila and has a 10% mortality rate.
341
What is the **mortality rate** of anthrax even with treatment?
~100% ## Footnote Post exposure prophylaxis includes ciprofloxacin/doxycycline for 60 days.
342
What is the **mortality rate** for GI anthrax?
50% ## Footnote There is no such thing as hematologic anthrax.
343
What are the **three forms** of the plague caused by Yersinia pestis?
* Bubonic * Septicemia * Pneumonic ## Footnote The bubonic form is transmitted via flea bites, while pneumonic plague can be transmitted through droplets.
344
What are the symptoms of **bubonic plague**?
* Fever * Malaise * Lymphadenopathy * Distal gangrene due to small artery thrombosis ## Footnote This form is also known as the 'black death'.
345
What is the **fatality rate** of pneumonic plague if not treated within 24 hours?
~100% ## Footnote Symptoms include fever, malaise, and bloody cough.
346
What is the **NAVA** in relation to asthma management?
Neurally Adjusted Ventilatory Assistance ## Footnote It reduces dyssynchrony and uses an esophageal catheter.
347
What is the recommended **tidal volume** for asthma management?
6 mL/Kg/IDEAL body weight ## Footnote The respiratory rate should be set to 12.
348
What is the **I/E ratio** for COPD management?
1:4 ## Footnote This involves low tidal volumes, low respiratory rate, and short inspiratory times.
349
What is the **indication** for using prolonged paralysis on a ventilator?
ARDS ## Footnote Neuromuscular-blocking agents have been associated with decreased mortality in intubated patients with acute respiratory distress syndrome.
350
What does the **RASS** scale measure?
Richmond Agitation-Sedation Scale ## Footnote It ranges from -5 (GCS of 3) to +4 (combative).
351
What is the **most common cause** of neonatal seizures?
Hypoxia encephalopathy ## Footnote It accounts for 55% of seizures in neonates.
352
What is the treatment for **breast milk jaundice** in neonates?
* Increase breastfeeding * Supplement with formula ## Footnote Early type occurs due to neonatal dehydration, while late type is due to molecules in breast milk.
353
What is the **first-line treatment** for tuberculosis?
* Isoniazid * Rifampin * Pyrazinamide * Ethambutol * Rifabutin * Rifapentine ## Footnote These are used for the treatment of Mycobacterium tuberculosis.
354
What is the **duration of therapy** for tuberculosis of the hip joint?
6-9 months ## Footnote Tuberculous meningitis requires 9-12 months of therapy.
355
What is the **most common cause** of hemolytic transfusion reactions?
Clerical error ## Footnote This is the leading cause of transfusion-related complications.
356
What is the **PR interval** duration for heart block?
200 ms ## Footnote The PR segment is 120 ms.
357
What is the **blood supply** for the AV node?
* 90% AV nodal artery via R. coronary artery * 10% AV nodal artery via L. circumflex artery ## Footnote This is crucial for understanding cardiac conduction.
358
What is the **treatment** for neonatal sepsis?
IV antibiotics ## Footnote Neonatal sepsis can cause seeding of the kidneys and UTIs.
359
What is the **indication** for chest compressions in neonatal CPR?
HR < 60 AND signs of poor perfusion ## Footnote This is prioritized before intubation.
360
What is the **maximum dose** of epinephrine for pediatric resuscitation?
0.1 mg ## Footnote The IV/IO dose is 0.01 mg/kg.
361
What is the **treatment** for miliary TB?
* Prednisone 60 mg q day * 4 antibiotics x 12 months ## Footnote This includes Rifampin, INH, pyrazinamide, and ethambutol.
362
What is the **first-line treatment** for pediatric pulmonary TB?
* INH * Rifampin * Pyrazinamide (only first 2 months) * Ethambutol ## Footnote Ethambutol can cause vision changes.
363
What is the **cause** of false-positive guaiac tests?
* Turnips * Vitamin C * Horseradish ## Footnote These foods can interfere with test results.
364
What is the **most common cancer** in individuals under 15 years old?
ALL (acute lymphocytic leukemia) ## Footnote This type of leukemia is characterized by the overproduction of immature lymphocytes.
365
In **sickle cell disease**, what is the treatment for **Acute Chest Syndrome**?
* IVF * Oxygen * Antibiotics * Pain medications * Blood transfusion/exchange transfusion ## Footnote Hydroxyurea is used prophylactically to prevent crises.
366
What are the **common bacteria** associated with **sickle cell disease** complications?
* Mycoplasma pneumonia * Chlamydia pneumoniae * Strep pneumonia * H. influenzae * N. meningitidis * Klebsiella pneumonia * E. coli * Salmonella ## Footnote These bacteria are particularly dangerous due to the compromised spleen function in sickle cell patients.
367
What is the **reticulocyte count** in an **aplastic crisis**?
Decreased ## Footnote This is often due to folate deficiency or a post-infectious process.
368
In **iron deficiency anemia**, what is the **serum ferritin** level?
Low ## Footnote Ferritin is a marker of stored iron in the body.
369
True or false: **Lead poisoning** can cause **microcytic anemia**.
TRUE ## Footnote Lead interferes with hemoglobin synthesis, leading to microcytic anemia.
370
What is the **TIBC** level in **anemia of chronic disease**?
Low ## Footnote TIBC (Total Iron Binding Capacity) reflects the body's iron availability.
371
What are the **characteristics** of **sideroblastic anemia**?
* Microcytic * Hypochromic ## Footnote This type of anemia is characterized by the presence of ringed sideroblasts in the bone marrow.
372
What is the **LDH** level in **hemolytic anemia**?
Increased ## Footnote LDH (Lactate Dehydrogenase) is released during the breakdown of red blood cells.
373
What is the **indirect bilirubin** level in **hemolytic anemia**?
Increased ## Footnote Indirect bilirubin is elevated due to increased breakdown of hemoglobin.
374
What is the **most common treatment** for **gonorrhea**?
Ceftriaxone 500mg IM x1 ## Footnote This treatment is effective for genital infections.
375
What is the **incubation period** for **chlamydia**?
1-3 weeks ## Footnote Many individuals are asymptomatic during this period.
376
What is the **treatment** for **primary syphilis**?
PCN G benzathine 2.4 million units IM x one ## Footnote Treatment should be administered within 24 hours to avoid Jarisch-Herxheimer reaction.
377
What are the **four stages** of **pericarditis**?
* PR depression with diffuse ST segment elevation * Normal ECG * Diffuse T wave inversion * Normal ECG or permanent T wave inversion ## Footnote The first stage is often associated with viral infections.
378
What is the **Hoffman Reflex** indicative of?
Cervical myelopathy ## Footnote A positive Hoffman reflex suggests a lesion above the origin of the brachial plexus.
379
What is the **treatment** for **HIV esophagitis** caused by **Candida**?
Fluconazole ## Footnote If treatment fails, consider CMV infection.
380
What is the **CD4 count** that indicates **AIDS**?
< 200 ## Footnote This count signifies severe immunosuppression.
381
What is the **first-line treatment** for **aortic dissection**?
Esmolol ## Footnote This medication helps control blood pressure and heart rate.
382
What is the **risk factor** for **aortic dissection** in individuals under 40?
Marfan syndrome ## Footnote Marfan syndrome is a connective tissue disorder that increases the risk of aortic dissection.
383
What is the **most common location** for an **aortoenteric fistula**?
Distal half of Duodenum ## Footnote This condition can lead to massive upper GI bleeding.
384
What is the **treatment** for **scabies**?
Permethrin cream 5% ## Footnote The cream should be washed off after 8 hours.
385
What is the **characteristic rash** of **HSV**?
Painless vesicular lesions ## Footnote HSV can transmit even without symptoms.
386
What is the **treatment** for **bacterial vaginosis**?
* Metronidazole 500mg bid x 7d * Vag metro gel 0.75% 5G x 5d * Vag clindamycin 2% cream QHS x 7d ## Footnote All symptomatic women should be treated.
387
What is the **treatment** for **chancroid**?
Ceftriaxone 500mg IM x1 ## Footnote This is effective for genital ulcers caused by Haemophilus ducreyi.
388
What is the **treatment** for **polymyalgia rheumatica**?
Corticosteroids ## Footnote This condition typically affects individuals over age 50.
389
What is the **risk factor** for **endometritis**?
* C-section * Retained products of conception * Premature rupture of membranes * Intrauterine monitoring device * Young maternal age * Frequent vaginal exams ## Footnote These factors increase the likelihood of developing endometritis.
390
What is the **treatment** for **alcoholic ketoacidosis**?
IV fluids and glucose ## Footnote This condition typically occurs after a binge drinking episode.
391
What is the **most common cause** of **myocarditis** worldwide?
Chagas disease (Trypanosoma cruzi) ## Footnote This parasitic infection is prevalent in Latin America.
392
What is the **treatment** for **acute graft rejection**?
Immunosuppressive therapy ## Footnote This is necessary to manage the cellular response.
393
What is the leading cause of **myocarditis** worldwide?
Chagas disease (Trypanosoma cruzi) ## Footnote Chagas disease is a significant concern in regions where it is endemic.
394
What are the components of **Beck’s Triad**?
* Hypotension * Muffled heart sounds * Jugular venous distension ## Footnote Beck's Triad is associated with cardiac tamponade.
395
What is **priapism**?
Painful erection lasting > 2 hours ## Footnote Untreated priapism can lead to 35% impotence due to fibrosis in the corpus cavernosum.
396
What are the two types of **priapism**?
* Low-Flow (ischemic) * High-Flow (non-ischemic) ## Footnote Low-Flow is painful and often associated with conditions like sickle cell disease, while High-Flow is non-painful and often due to trauma.
397
What does a **red flag** indicate at the beach?
Unsafe conditions, beach closed for swimming ## Footnote Beach flags communicate water safety conditions.
398
What is the **sensitivity** of Pulsus Paradoxus for Tamponade?
> 10 mm Hg has sensitivity of 82% ## Footnote Pulsus Paradoxus is a clinical sign observed in cardiac tamponade.
399
What is the **most common** cause of pediatric parotitis?
Mumps ## Footnote Mumps starts unilateral but can become bilateral in 70% of cases.
400
What is the **treatment** for acute necrotizing ulcerative gingivitis (ANUG)?
Dilute 3% hydrogen peroxide mouth rinses and PO antibiotics for 7-10 days ## Footnote ANUG is characterized by pain, ulcerated interdental papillae, and gingival bleeding.
401
What is the **most common** site for salivary gland stones (sialolithiasis)?
Submandibular gland (80%) ## Footnote The submandibular gland has the longest duct and lowest saliva flow, leading to stone formation.
402
What is the **diagnosis** for Pseudotumor Cerebri?
LP opening pressure ## Footnote Non-obese patients > 20 cmH20, obese patients > 25 cmH20.
403
What is the **first step** in rabies postexposure prophylaxis?
Wash wound with SOAP/H2O then clean with IODINE ## Footnote This is crucial to prevent rabies infection.
404
What is the **mortality rate** for pulmonary anthrax?
~100% mortality (even with treatment) ## Footnote Pulmonary anthrax is the most lethal form of anthrax.
405
What are the **Ottawa knee rules** for radiography necessity?
* Patient age > 55 years * Cannot transfer weight from one foot to the next * Cannot flex knee 90 degrees * Patellar tenderness without other bone tenderness * Tenderness in the fibular head ## Footnote These rules help determine the need for knee X-rays.
406
What is the **most serious** injury associated with posterior elbow dislocation?
Brachial artery injury (8%) ## Footnote This injury can lead to significant complications.
407
What is the **most common** type of rotator cuff tear?
Supraspinatus tear ## Footnote Pain is often worse at night and over the greater tuberosity.
408
What is the **treatment** for a Boxer's fracture?
Ulnar gutter splint in position of function ## Footnote This is for a 5th metacarpal fracture with ≤ 45˚ angulation.
409
What is the **characteristic** of a painless ulcer?
Syphilis ## Footnote This is the only ulcer that is typically painless.
410
What is the **treatment** for Legionnaires Disease?
Ciprofloxacin or doxycycline ## Footnote This disease is caused by Legionella pneumophila and has a 10% mortality rate.
411
What is the **mortality rate** of anthrax even with treatment?
~100% ## Footnote Post exposure prophylaxis includes ciprofloxacin/doxycycline for 60 days.
412
What is the **mortality rate** for GI anthrax?
50% ## Footnote There is no such thing as hematologic anthrax.
413
What are the **three forms** of the plague caused by Yersinia pestis?
* Bubonic * Septicemia * Pneumonic ## Footnote The bubonic form is transmitted via flea bites, while pneumonic plague can be transmitted through droplets.
414
What are the symptoms of **bubonic plague**?
* Fever * Malaise * Lymphadenopathy * Distal gangrene due to small artery thrombosis ## Footnote This form is also known as the 'black death'.
415
What is the **fatality rate** of pneumonic plague if not treated within 24 hours?
~100% ## Footnote Symptoms include fever, malaise, and bloody cough.
416
What is the **NAVA** in relation to asthma management?
Neurally Adjusted Ventilatory Assistance ## Footnote It reduces dyssynchrony and uses an esophageal catheter.
417
What is the recommended **tidal volume** for asthma management?
6 mL/Kg/IDEAL body weight ## Footnote The respiratory rate should be set to 12.
418
What is the **I/E ratio** for COPD management?
1:4 Inspiration time 1 : 4 Expiration time ## Footnote This involves low tidal volumes, low respiratory rate, and short inspiratory times.
419
What is the **indication** for using prolonged paralysis on a ventilator?
ARDS ## Footnote Neuromuscular-blocking agents have been associated with decreased mortality in intubated patients with acute respiratory distress syndrome.
420
What does the **RASS** scale measure?
Richmond Agitation-Sedation Scale ## Footnote It ranges from -5 (GCS of 3) to +4 (combative).
421
What is the **most common cause** of neonatal seizures?
Hypoxia encephalopathy ## Footnote It accounts for 55% of seizures in neonates.
422
What is the treatment for **breast milk jaundice** in neonates?
* Increase breastfeeding * Supplement with formula ## Footnote Early type occurs due to neonatal dehydration, while late type is due to molecules in breast milk.
423
What is the **first-line treatment** for tuberculosis?
* Isoniazid * Rifampin * Pyrazinamide * Ethambutol * Rifabutin * Rifapentine ## Footnote These are used for the treatment of Mycobacterium tuberculosis.
424
What is the **duration of therapy** for tuberculosis of the hip joint?
6-9 months ## Footnote Tuberculous meningitis requires 9-12 months of therapy.
425
What is the **most common cause** of hemolytic transfusion reactions?
Clerical error ## Footnote This is the leading cause of transfusion-related complications.
426
What is the **PR interval** duration for heart block?
200 ms ## Footnote The PR segment is 120 ms.
427
What is the **blood supply** for the AV node?
* 90% AV nodal artery via R. coronary artery * 10% AV nodal artery via L. circumflex artery ## Footnote This is crucial for understanding cardiac conduction.
428
What is the **treatment** for neonatal sepsis?
IV antibiotics ## Footnote Neonatal sepsis can cause seeding of the kidneys and UTIs.
429
What is the **indication** for chest compressions in neonatal CPR?
HR < 60 AND signs of poor perfusion ## Footnote This is prioritized before intubation.
430
What is the **maximum dose** of epinephrine for pediatric resuscitation?
0.1 mg ## Footnote The IV/IO dose is 0.01 mg/kg.
431
What is the **treatment** for miliary TB?
* Prednisone 60 mg q day * 4 antibiotics x 12 months ## Footnote This includes Rifampin, INH, pyrazinamide, and ethambutol.
432
What is the **first-line treatment** for pediatric pulmonary TB?
* INH * Rifampin * Pyrazinamide (only first 2 months) * Ethambutol ## Footnote Ethambutol can cause vision changes.
433
What is the **cause** of false-positive guaiac tests?
* Turnips * Vitamin C * Horseradish ## Footnote These foods can interfere with test results.
434
STEMI + RIGHT axis deviation (large S in lead I) → what other 2 emergent processes should be evaluated first 
PE HYPERK
435
when is it semi and not acute pericarditis?
1. ** any ST depression**→ this will not occur in pericarditis 2. **ST elevation in lead three greater than lead to** → increased odds ratio that this is a ischemic process and not pericarditis 3. ** flattening or convexed ST segments**→ pericarditis will always keep the concaved ST segment 
436
Hydroxocobalamin is used to treat what two toxicities?
Cyanide Natural gas exposure 
437
RIGHT ventricular hypertrophy ecg