Recognising Toxicity

Question 1

What are the signs of digoxin toxicity?

Answer 1

• Lack of appetite, nausea, vomiting, or diarrhea
• Headache, confusion, anxiety, or hallucinations
• Restlessness, weakness, or depression
• Changes in vision such as blurred vision or seeing halos around bright objects
• A fast, slow, or irregular heartbeat, or palpitations (fast, forceful heartbeats in an irregular rhythm)

Question 2

What are the signs of theophylline toxicity?

Answer 2

vomiting
Abdominal pain
hypokalemia
hyperglycemia
metabolic acidosis
seizures
sinus tachycardia and other tachyarrhythmias (SVT, VT)
hypotension
Tremors

Question 3

What are the signs of phenytoin toxicity?

Answer 3

Nystagmus 
Ataxia 
Unsteady gait
Lethargy
Confusion 
N + V

Question 4

What are the signs of lithium toxicity?

Answer 4

GI disturbances (vomiting, diarrhoea)
visual disturbances
polyuria
muscle weakness
tremor
CNS disturbances (confusion, drowsiness, lack of coordination, restlessness)
abnormal reflexes
hypernatraemia 
cardiac arrhythmias