1
Q
Describe evolution of LH + FSH throughout life
(WG p 318)
A
Onset: 15 weeks
Peak: 30 week → decrease to birth
Low (ish) at birth
Peak at 3 months (response to ↓ estrogen from placenta)
Low from age 1-2 until puberty
High in menopause
2
Q
Describe the evolution of oovocyte numbers and mechanisms of “death”
WG p 317
A
5 months: 6-7 million
Birth : 1-2 million
Puberty: 300 - 500 000
In utero : apoptosis
Childhood: atresia
3
Q
Definition of primary amenorrhea
(Berek)
A
Absence of menses by age 13 with no visible development of secondary sexual characteristics Or
Absence of menses by age 15 in presence of normal secondary sexual characteristics
4
Q
Define secondary ammenorrhea
(Berek)
A
RC OBGYN (CG)
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