Renal

Question 1

Calcinuerin inhibitors

• cyclosporine
• tacrolimus

Answer 1

Cyclosporin:
Hypertension; decreased GFR; dyslipidemia; hirsutism

Tacrolimus:
New-onset diabetes mellitus; decreased GFR; hypertension; gastrointestinal symptoms

Question 2

Antimetabolite, blocker of de novo purine synthesis

• Mycophenolate
• azithoprine

Answer 2

Mycophenalate: Diarrhea; nausea/vomiting; leukopenia; anemia

Azithoprine: leukopenia

Question 3

mtor

sirolimus

Answer 3

Proteinuria; dyslipidemia; new-onset diabetes mellitus; anemia; leukopenia

Question 4

BPH

• Diagnosis
• Management

Answer 4

Diagnose:

• — LUTS sx
• — UA
• — Do not do a PSA
• — Exam: prostate smooth, enlarged. If nodular, indurated or asymmetric consider adenocarcinoma

Treatment:

• – UAU score < 8- conservative measures
• – UAU >/= 8 Pharmacologic measures
• —- alpha blockers
• —- Finasteride (only if prostate >40)

Question 5

Polycystic Kidney Disease

• Diagnosis
• Treatment
• Associated syndromes

Answer 5

Diagnosis: Proteinuria, hematuria, HTN, Bilateral Masses
Treatment: Treat HTN
Associated Syndromes:
- pancreatic and hepatic cysts
- diverticulosis
- intracranial aneurysm (SAH)
- Aortic valve disease and aortic root disease

Question 6

Who to Screen for Aneurysms in APCKD

Answer 6

1. Family hx of rupture
2. Personal hx of rupture
3. High risk profession

Screen with time of flight MRI

Question 7

AIN

Answer 7

Febrile
Rash
Eosinophilia
Eosinophiluria

Sterile pyuria with WBC casts
Hematuria
Eos

Biopsy (not required) inflammatory infiltrate, Edema

Treatment:

• remove offending agent (PPI, NSAID, antibiotics etc. )
• If does not improve may require Glucocorticoids

Question 8

CKD electrolyte (P and Ca goals)

Answer 8

PTH <300
Phos 3.5-5.5
Ca 8.4-9.5
CaxP product <55