Renal Patho

Question 1

Glomeruloneuropathies

Answer 1

• Decreased glomerular filtration
  
  • Decreased urine output
  • Increase plasma creatinine and urea

Question 2

Nephrosis

Answer 2

• Damage to glomerular membrane
• Enlargement of fenestrations
• Excretion of or more 3.5 g of protein in urine /day

Question 3

Clinical manifestations of nephrosis

Answer 3

Edema

Hypotension

Question 4

Nephrosis causes

Answer 4

• Hypertension
• Dibetes mellitus, destruction of capillary beds in glomerulus
• Type 3 immune complex, immune disorders
  
  • Lupus
  • Rheumatoid arthritis

Question 5

3 types of nephrosis

Answer 5

• Minimal change diseases
• Fecal segmental
• Membranous

Question 6

Minimal change disease

Answer 6

• Most common form in children
• Loss of foot processes
• Good prognosis

Question 7

Fecal segmental glomerulosclerosis

Answer 7

• Scarring of glomerulus
• primary or secondary
• Poor prognosis
• 3 Hs
  
  • HIV, heroin, hypertension

Question 8

Membranous Glomerulonephritis

Answer 8

• Autoimmune activation of immune complex
• Deposition of antibodies in basement mebrane
• Increased mebrane permeability and thickening