Renal Pathophys

Question 1

2 functions of ANP hormone?

Wh produces ANP in the body?

Answer 1

PRODUCTION: Atrium in response to high blood
pressure in the atria

FUNCTIONS:
1) increases water loss by vasocostricting efferent arteriole ad vasodilating the afferrent

2) Promotes Na+ loss via the increased filtration

Question 2

Fever, Rash and Oligouria =?

Answer 2

Acute interstial nephritis [aka Drug-induced interstial nephritis aka Tubulointerstial Nephritis]

Question 3

Which cell types are predominant in Drug-induced interstial nephritis

Answer 3

EOSINOPHILS and can also see other inflammatory infiltrates:

• -macrophages + granulomas in some cases
• plasma cells
• lymphocytes