Research Design

Question 1

Preclinical Research

Answer 1

Basic research

• in laboritories on animals
• focused on theory and understanding mechanisms of disease/therapies

Question 2

Clinical Research

Answer 2

applied research

• human subjects
• focused on testing theories that find new and better was to detect, diagnose, treat, and prevent disease or develop theories

Question 3

Model of clinical research process

Step 1

Answer 3

Identify the research questions

Question 4

Model of clinical research process

Step 2

Answer 4

Design the study

• who will be studied
• how subjects will be chosen
• what to measure
• what statistical methods for data analysis

Question 5

Model of clinical research process

Step 3

Answer 5

Implement the study

-collect data: most time consuming part of research process

Question 6

Model of clinical research process

Step 4

Answer 6

Analyze the data

-apply statistical procedures to summarize/explore quantitative info in a meaningful way

Question 7

Model of clinical research process

Step 5

Answer 7

Disseminate Findings

Question 8

Descriptive research

Answer 8

• qualitative and quantitative
• case report
• describe a group of individuals on a set of variables
• uses questionnaires, interviews, direct observation, or database

Question 9

Exploratory research

Answer 9

• observational without intervention
• find relationships between factors
• cohort studies
• case control studies

Question 10

Explanatory research

Answer 10

• Experimental with intervention
• establish cause and effect
• RCT

Question 11

Cohort study

Answer 11

select a cohort who don’t have outcome of interest and follow them to see if they develop disorder

Question 12

Case-Control study

Answer 12

select cases and controls and look back in time to determine if the groups differ with respect to their exposure histories

Question 13

Longitudinal study

Answer 13

follow a cohort of subjects over multiple points in time performing repeated measurements