Resp 1

Question 1

5 Stages of lung development

Answer 1

1. Embryonic Period
2. Pseudo - glandular period
3. Canalicular period
4. Saccular and alveolar period
5. Post natal period

Question 2

4 points of embryonic period

Answer 2

1. Respiratory diverticulum develops as an evagination from the foregut
2. Primitive trachea forms lung buds that fork to form primitive bronchi
3. Branching produces lobular bronchii
4. Lobes are surrounded by mesenchyme which will form visceral pleura

Question 3

What does the respiratory diverticulum devlop as?

Answer 3

An evagination from the forgut

Question 4

What are lobes in the embryonic period surrounded by?

Answer 4

Messenchyme which will form the visceral pleura

Question 5

What doe mesenchyme which is in direct contact of bronchi develop into?

Answer 5

Visceral Pleura

Question 6

What do lung bud branchings form?

Answer 6

Bronchi which develop into lobular bronchi

Question 7

3 Points to pseudo glandular period

Answer 7

1. Lobular bronchi give rise to segmental bronchi that undergo many bifurcations
2. Terminal bronchioles form
3. Cell differentiation

Question 8

What do lobular bronchi give rise to in pseudo glandular period?

Answer 8

Segmental bronchi that undergo many bifurcations

Question 9

What stage do terminal brochioles form?

Answer 9

Pseudo-glandular period

Question 10

What are 4 types of cells that differentiate in pseudo glandular period?

Answer 10

Epithelial cells

Cartilage

Submucosal Glands

Smooth Muscle

Question 11

Four points to canalicular period

Answer 11

1. Lumin of bronchi and broncioles enlarge, increased vascularization
2. Continued bifurcations and formation of terminal and respiratory bronchioles
3. Formation of areas of the lungs that will be involved in gas exchange
4. Respiratory bronchioles form canaliculi and terminal saccules

Question 12

What allows for increase vascularization during canalicular period?

Answer 12

Lumina of bronchi and bronchioles enlarge

Question 13

During what period do respiratory bronchioles form canaliculi and terminal saccules?

Answer 13

Canalicular period

Question 14

What occurs durring saccular and alveolar periods?

Answer 14

Epithelium of primitive alveoli differentiate into type I and type II alveolar cells

Question 15

During which period are type I and type II alveolar cells formed?

Answer 15

Saccular and alveolar periods

Question 16

What do type II aveolar cells produce?

Answer 16

Surfactant

Question 17

What occurs to lungs after first breath?

Answer 17

Mature alveoli become functional, additional alveolar development

Question 18

What occurs durring post natal period?

Answer 18

Mature alveoli become functional

Longitudinal growth of bronchioles

Question 19

Define mesenchyme

Answer 19

Undifferentiated connective tissue derived primarily from misoderm

Question 20

Define primordia

Answer 20

Organ or tissue in its earliest recognizable development

Question 21

Define Neuroectoderm

Answer 21

Neural tissue derived from ectoderm

Question 22

Define Ectomesenchyme

Answer 22

Mesenchyme derived from neuroectoderm (nerual crest cells)