aka: infant respiratory distress syndrome (IRDS)
hyaline membrane disease
define INFANT RESPIRATORY DISTRESS SYNDROME
acute hypoxemia caused by infiltrates within alveoli
s/s: infant respiratory distress syndrome
nasal flaring, grunting respirations, sternal retractions, reduced oxygen tension, ineffective gas exchange, cyanotic w/mottled skin
cause: IRDS
baby lacks surfactant to allow alveoli to expand causing inadequate surface area for proper gas exchange
tx: IRDS
prevention methods for IRDS?
inject mom w/corticosteroid 24 hours before delivery
cause of laryngomalacia, tracheomalacia, & bronchomalacia
softened/underdeveloped cartilage causing airway to partially or completely collapse
define BRONCHOPULMONARY DYSPLASIA (BPD)
chronic lung disease causing lungs to be stiff, obstructed, and hard to ventilate in baby after insult to neonate’s lungs
what may be a sequela to IRDS, lung infection, or extreme maturity
bronchopulmonary dysplasia
s/s: bronchopulmonary dysplasia
periods of dyspnea, tachypnea, wheezing, cyanosis, nasal flaring, sternal retractions, O2 sat decrease, heart rate decrease, cough, difficulty feeding, working hard to breathe, poor posture of neck/shoulders/upper body, wet/crackling sounds in lungs
cause: bronchopulmonary dysplasia
why does mechanical ventilation w/supplemental oxygen cause bronchopulmonary dysplasia
pressure & O2 damage lung tissue causing overinflation/scarring
how is bronchopulmonary dysplasia diagnosed
tx: bronchopulmonary dysplasia
prognosis of bronchopulmonary dysplasia
good w/early & aggressive intervention
complications of bronchopulmonary dysplasia?
pulmonary edema, hypertension, right-sided heart failure, respiratory infections, apnea, tracheomalacia, asthma, GI reflux, aspiration, susceptible to respiratory infections, poor growth, delayed development
prevention for bronchopulmonary dysplasia
none; early weaning from mechanical respiratory
define CYSTIC FIBROSIS
chronic dysfunction of gene affecting multiple body systems
what is the most common fatal genetic disease
cystic fibrosis
sx: cystic fibrosis
cause: cystic fibrosis
autosomal recessive disorder; chronic dysfunction of gene cystic fibrosis transmembrane conductance regulator (CFTR)
how is cystic fibrosis diagnosed
genetic testing, family history, pulmonary function test, chest xray, stool study, sweat test
tx: cystic fibrosis
what is the life expectancy of someone with cystic fibrosis
30s