Retention

Question 1

post obstructive diuresis

Answer 1

poor response of collecting duct to ADH - pathological
increased production of ANP
inability to maintain meduallary solute gradient due to increase blood flow
defective medullary solute gradient (reduced NaCl and urea reabsorption)

Question 2

physiological aspect post ob diuresis

Answer 2

accumulation solutes

volume expansion

Question 3

recovery renal function after HPCR
glomerular vs tubular recovery
% of creatinine clearance tubular vs glomerule

Answer 3

can take 3 months
creatinine excreated by tubules as well as through glomerular filtration
tubules recover 14 days
glomerular function can take 3 months
80% creatinine clearance due to GFR
20% due to renal tubular secreation