increased transcription when I/G is high
FA Synthesis:
acetyl CoA carboxylase
fatty acid synthase
glucose 6-P dehydrogenase
(glycerol 3-P acyltransferase - adds FA to glycerol backbone)
Glycolysis:
glucokinase
PFK-1
PK (PEP -> pyruvate + ATP)
locations of G protein coupled receptors
liver and fat
not found on skel mm
significanse of glycerol kinase
allows liver to perform glucogenesis from glycerol (FA degradation)
glycerol -(glycerol kinase) -> glycerol 3-P -> DHAP -> glucose
one of 2 paths into glucogenesis in the liver