Could be REGULATORY TYPE or AMORPH
Have membrane abnormalities that shorten RBC survival and cause HA
If Anti-Rh is detected, Rhnull cells are needed for transfusion
Rhnull
partial suppression of Rh antigens due to the inheritance of modified RHAG gene
Rhmod
(HDFN)
Hemolytic Disease of the Fetus and Newborn
The LW Blood Group System
CHROMOSOME____
19
LW BGS
Alleles:
LW^a, LW^b, LW
LW BGS
Most common phenotype:
LW(a+b-)
LW BGS
Amorph gene:
Null phenotype:
LW
LW(a-b-)
Similar to Rh serologically Different to Rh genetically
LW BGS
Reacts strongly with D positive red cells
Clinically insignificant and rafe
Anti-LW