Rh & ABO

Question 2

def of Rh Isoimmunization

Answer 2

Question 3

Etiology of Rh Isoimmunization

Answer 3

Question 4

Etiology of Rh Isoimmunization

• Any contact () Rh + ve fetal blood & maternal circulation

Answer 4

Question 5

Etiology of Rh Isoimmunization

• Blood transfusion of Rh +ve blood to Rh -ve female at any age

Answer 5

…

Question 6

CP of Rh Isoimmunization

Question 7

CP of Rh Isoimmunization

• Degrees

Answer 7

• Congenital hemolytic anemia: Mildest form
• Icterus gravis neonatorum: Commonest form
• Fetal hydrops: Rarest & most severe form

Question 8

CP of Rh Isoimmunization

• Icterus gravis neonatorum

Answer 8

Question 9

Dx of Rh Isoimmunziation

• US

Answer 9

Question 10

Spectrophotometric analysis of AF in Rh Isoimmunization

• Indications

Answer 10

Question 11

Fetal Blood Sampling in Rh Isoimmunization

Answer 11

Question 12

Fetal Blood Sampling in Rh Isoimmunization

• Aim

Answer 12

Question 13

Fetal Blood Sampling in Rh Isoimmunization

• Disadvantages

Answer 13

Complications of cordocentesis:

1. More risky than serial amniocentesis.
2. Feto-maternal Hge & consequently, massive ↑↑ in concentration of Abs.
3. Thrombosis of umbilical vessels.
4. Risk of fetal death (1.5%).

Question 14

Neonatal Blood Sampling in Rh Isoimmunization

Answer 14

Question 15

Prevention of Rh Isoimmunization

Answer 15

• Prevention of blood transfusion errors
• Anti-D Ig administration

Question 16

Prevention of Rh Isoimmunization

• Prevention of blood transfusion errors

Answer 16

Never to give Rh +ve blood to Rh -ve females.

Question 17

Prevention of Rh Isoimmunization

• Anti-D Ig administration

Answer 17

Question 18

Anti-D Ig administration in Rh Isoimmunization

• Value

Answer 18

Anti-D Ig will destroy Rh +ve RBCs in maternal Circulation before sensitization.

Question 19

Anti-D Ig administration in Rh Isoimmunization

• indications

Answer 19

Question 20

Anti-D Ig administration in Rh Isoimmunization

• time of adminstartion

Answer 20

Within 72 hours after sensitizing event.

Question 21

Anti-D Ig administration in Rh Isoimmunization

• Calculation of Dose

Answer 21

Question 22

Plan managment in Rh Isoimmunization

• Algorithm

Answer 22

Question 23

Intrauterine transfusion (IUT) in Rh Isoimmunization

• indications

Answer 23

• Fetal hydrops
• significant fetal anemia (Hb deficit > 2 gm/dl from mean for normal fetuses or Hct value < 30%).

Question 24

Neonatal Care in Rh Isoimmunization

• exchange Transfusion

Answer 24

Question 25

Criteria to Dx **ABO Isoimmunization**

Answer 25

Question 26

Def of **Non-Immune Fetal Hydrops**

Answer 26

Question 27

Etiology of **Non-Immune Fetal Hydrops**

Answer 27

Question 28

Dx of **Non-Immune Fetal Hydrops**

Answer 28