Rickets

Question 1

What is Ricketts?

Answer 1

Clinical manifestation of calcium, phosphate or vitamin D deficiency in children

Question 2

What type of genetic condition is Ricketts?

Answer 2

X-linked dominant condition

Question 3

How does Rickett’s present?

Answer 3

• Poor growth and development
• Muscle weakness
• Bone and joint pain
• Constipation
• Delayed dentition

Question 4

What bone deformities can occur in Rickets?

Answer 4

• Craniotabes
• Bow knees
• Knock knees
• Rachitic Rosary

Question 5

How would you diagnose Rickets?

Answer 5

• X-ray
• 25-hydroxyvitaminD
• Calcium and phosphate deficiency
• PTH and ALP raised

Question 6

What would you see on an x-ray of someone with Rickets?

Answer 6

Widened epiphyseal plate

Question 7

What would the level of 25-hydroxyvitaminD be to diagnose Rickets?

Answer 7

Less than 25ng/mol

Question 8

What are risk factors for Rickets?

Answer 8

Malabsorption
Chronic kidney disease
Lack of sun exposure
Poor nutrition

Question 9

What can malabsorption be due to?

Answer 9

Coeliac

IBD

Question 10

What is the management of Rickets?

Answer 10

Oral vitamin D

Question 11

What does Falconi syndrome include?

Answer 11

• Type 2 renal tubular acidosis
• Rickets/osteomalacia
• Polyuria

Question 12

What is the main cause of Rickets?

Answer 12

Prolonged lack of sufficient vitamin D

Question 13

What can a prolonged lack of vitamin D result in?

Answer 13

An inability to absorb calcium and phosphorous from food.