RNA

Question 1

Identify the virus:

• virulence factors: hemagglutinin + neuraminidase
• media: amniotic cavity of embryonated chicken eggs
• mot: aerosols + zoonotic
• disease: common colds to pneumonia

Answer 1

Influenzavirus A

Orthomyxoviridae

Question 2

Identify the strain of influenzavirus:

Spanish flu

Answer 2

H1N1

Question 3

Identify the strain of influenzavirus:

Asian flu

Answer 3

H2N2

Question 4

Identify the strain of influenzavirus:

Hongkong flu

Answer 4

H3N2

Question 5

Identify the strain of influenzavirus:

Avian flu

Answer 5

H5N1

Question 6

Identify the strain of influenzavirus:

Swine flu

Answer 6

H1N1

Question 7

Identify the virus:

• croup in infants
• virulence factors: HN + Fusion (F)

Answer 7

Parainfluenza virus

Paramyxovirus

Question 8

Identify the virus:

mumps (swelling of the parotid glands - parotitis)

Answer 8

Rubula virus

Paramyxoviridae

Question 9

Identify the virus:

• measles (maculopapular rash and koplik’s spots)
• contains hemolysin A

Answer 9

Morbilivirus (Rubeola)

Paramyxoviridae

Question 10

Identify the virus:

• rodent-borne
• hemorrhagic fever and encephalitis
• old-world: lymphocytic choriomeningitis and Lassa virus
• new-world: Junin, Machupo

Answer 10

Arenavirus

Arenaviridae

Question 11

Identify the family virus:

• arboviral: Rift valley fever, LaCrosse virus, California encephalitis virus, Crimean Congo hemorrhagic fever
• rodent-borne: Hantavirus (Hantaan virus, Seoul virus, Puumala virus, Dobrava virus)

Answer 11

Bunyaviridae

Question 12

Identify the virus:

• animal bite + inhalation of aerosols
• bullet-shaped
• CPE: negri bodies

Answer 12

Lyssavirus (rabies)

Rhabdoviridae

Question 13

Identify the virus:

German (3-day) measles

face, trunk, and limbs

Answer 13

Rubella (rubivirus)

Togaviridae

Question 14

Identify the virus:

• mosquito-borne
• birds-reservoir
• eastern, western and Venezuelan equine encephalitis

Answer 14

Alphavirus

Togaviridae

Question 15

Identify the virus:

• by Aedes spp. mosquito
• break bone fever
• self-limiting: 1-2 weeks

Answer 15

Dengue virus

Flaviviridae

Question 16

Identify the virus:

• monkey > aedes mosquito > human
• fever, jaundice, and kidney failure

Answer 16

Yellow fever virus

Flaviviridae

Question 17

Identify the virus:

• by Aedes and Culex
• monkeys > mosquito > humans
• fever, maculopapular rash (trunk, limbs) and joint pain

Answer 17

Chikungunya virus

Flaviviridae

Question 18

Identify the virus:

• by Culex spp.
• bird > mosquito > humans
• fever with meningoencephalitis

Answer 18

St. Louis Encephalitis virus

Flaviviridae

Question 19

Identify the virus:

• by Culex spp.
• birds reservoir
• swollen lymph glands + neuroinvasive

Answer 19

West Nile virus

Flaviviridae

Question 20

Identify the virus:

• by Culex spp.
• painful neck stiffness

Answer 20

Japanese encephalitis virus

Question 21

Identify the virus:

targets CD4+ T cells, monocytes, and macrophages

Answer 21

HIV

Retroviridae (contains reverse transcriptase)

Question 22

Identify the virus:

T cell leukemia, sarcoma, lymphoma, and tropical spastic paralysis

Answer 22

Human T Cell Lymphotropic Type 1 (HTLV)

Oncornavirus - Retroviridae

Question 23

Identify the virus:

hand, foot, and mouth disease

Answer 23

Coxsackie virus

Picornaviridae

Question 24

Identify the virus:

resistant to detergent, lipid solvents and extreme temperatures.

Answer 24

Rhinovirus

Picornaviridae

Question 25

# Identify the virus: - outbreaks in schools, resorts and cruise ships - human gastroenteritis - non-culturable

Answer 25

Norovirus (norwalk) | Caliciviridae

Question 26

# Identify the virus: - cup-shaped - sporadic case of gastroenteritis

Answer 26

Sapovirus | Caliciviridae

Question 27

# Identify the virus: - most common gastroenteritis in infants and children - double-shelled capsule/wheel

Answer 27

Rotavirus | Reoviridae

Question 28

# Identify the virus: - vector: *Dermacentor andersoni* - fever, myalgia, photophobia, arthralgia and hemorrhagic fever

Answer 28

Colorado Tick Fever (Coltivirus) | Reoviridae

Question 29

What is the only family of dsRNA?

Answer 29

Reoviridae | *Rotavirus* and *Coltivirus*

Question 30

human receptor of SARS-CoV

Answer 30

ACE2

Question 31

human receptor of MERS-CoV

Answer 31

dipeptidyl peptidase 4

Question 32

Quantitate the infectious titer of viruses

Answer 32

Plaque assay

Question 33

Causes secondary infection: *subacute sclerosing panencephalitis*

Answer 33

**Rubeola virus** (*Morbillivirus*) | Paramyxoviridae

Question 34

Most common cause of viral pneumonia in adults

Answer 34

Influenza and adenovirus

Question 35

# Evaluate the hepatitis panel: (+) Total anti-HBC (+) HbeAg (+) HbsAg

Answer 35

Acute-chronic infection

Question 36

bird-borne encephalitis

Answer 36

West nile and St. Louis | Flaviviridae

Question 37

vero cells serves as a medium for?

Answer 37

cytophatic effects

Question 38

# Which of the following is most likely to **cause a pandemic**? 1. Influenza A 2. S. pyogenes 3. Respiratory syncytial virus 4. Vaccinia virus

Answer 38

Influenza A virus | Orthomyxoviridae

Question 39

conjunctivitis viruses

Answer 39

* HSV * adenovirus * enterovirus * VSV

Question 40

neonatal viruses

Answer 40

* HSV-1&2 * CMV * enterovirus * parvovirus * rubella