Saccharine
Sweet
Sacrilege
A violation of something sacred
Sacrosanct
Sacred
Sagacious
Wise
Salient
Sticking out
Salutary
Healthful
Sanctimonious
Affecting religious feeling
Sanguine
Cheerful
Sardonic
Mocking
Scintillate
To sparkle
Scrupulous
Careful
Scrutinize
To examine very carefully
Secular
Having nothing to do with religion or spiritual concerns
Sedition
Treason
Segregate
To separate
Sensory
Having to do with the senses or sensation
Sentient
Able to perceive by the senses
Sequester
To set or keep apart
Serendipity
Accidental good fortune
Servile
Like a servant
Singular
Exceptional
Sinister
Evil
Slander
To defame
Sloth
Laziness