Sara Gordon

Question 1

Top three sexually transmitted disease i the us?

Answer 1

1) Chlamydia
2) Gonorrhea
3) Syphilis

Question 2

What are the three species of Chlamydia and which diseases do they cause?

Answer 2

1) C trachomatis (#1 sex transmitted disease) → Mucous membrane disease (genitals, oral mucosa, infant pneumonia)
2) C pneumoniae → respiratory (pharyngitis, brochitis, pneumonia)
3) C psittaci → psittacossis (birds) Mild fever, headache, dry cough, sometimes pneumonia)

Question 3

Which species is responsible for Gonococcal stomatitis?

Answer 3

Neisseria gonorrhea g- intracellular diplococcus

Question 4

How is gonococcal stomatitis transmitted?

Answer 4

Sexual and maybe kissing an infected person

Question 5

What are the symptoms of gonococcal stomatitis?

Answer 5

Usually asymptomatic,

pharyngitis, tonsilitis, fever, swollen lymph nodes

Question 6

What is the causative agent for syphilis?

Answer 6

Treponema pallidum, corkscrew, motile, need darkfield/ fluoresc to see

Question 7

What are the three stages of syphilis? What is the likelihood of progression? When is it transmittable?

Answer 7

primary, secondary, tertiary ⅔ progress onto next stage ⅓ clears on its own

Transmittable at any stage, also can be passed to infant during pregnancy, any stage

Question 8

What are the the clinical manifestations of primary syphilis? when does it appear?

Answer 8

1-3 weeks post contact,

1) Chancre (macule→papule→ulcer) on the site of inoculation
2) regional lymphadenopathy (rubbery, painless, bilateral)
3) blood test may not be + during early primary syphilis

Question 9

What are the clinical features of secondary syphilis?

Answer 9

Dissemination of spirochetes

3-6 weeks after 1 chancre

persists weeks - months

blood tests are highers in titer in this stage!

1. Skin rash (hands and feets!!)75-100%
2. Lymphadenopathy
3. malaise
4. Mucous pathes (6-30%)
5. condylomata lata (10-20%)
6. Hair loss-5%

Question 10

What is condyloma lata?

Answer 10

secondary syphilis,

grayish papules on infected genitals (ass. with skin rash)

Question 11

What is latent syphilis?

Answer 11

May occur between primary and secondary, and after secondary

no clinical lesions

Question 12

What are the clinical signs of tertiary syphilis? Likelihood of progression?

Answer 12

30% of untreated progress within 1-20 yrs

1. Gummas -gummatous lesions
2. cardiovascular syphilis
3. neurosyphilis

Question 13

List three major oral manifestations of tertiary syphilis?

Answer 13

1. gumma - palate midline, tongue or tonsils. Bone destruction -palatal perforation!
2. Luetic glossitis -was linked to cancer, but no because it was tx with arsenic lol
3. painless swelling of the parotid gland-rare

Question 14

Describe gamma and what disease is it linked to? where does it classically appear?

Answer 14

gummatous necrosis = tertiary syphilis

Gummatous necrosis at the center of granulomas -variation of coagulation necrosis

classical appearance - hard palate

Question 15

What are the orofacial features of congenital syphilis?

Answer 15

1. Rhagades (infected fissures, oral comissures)
2. Frotal bossing
3. Perforation of palate (bacteria→tissue damage)
4. Saddle nose
5. Mucous patches (secondary and congenital)
6. Hutchinson triad (deaf, blind, Malformed teeth→hutchinson’s incisors, mulberry teeth)
7. short maxilla

Question 16

What is the causative agent for cat scratch disease?

Answer 16

Bartonella henselae

g- bacilus, 90% bc contact with cat, reactive lympadenitis

Question 17

Whats the causative agent for diphtheria?

Answer 17

Klebs-Loeffler bacterium/ Corynebacterium

Question 18

Whats the causative agent for diphtheria?

Answer 18

Klebs-Loeffler bacterium/ Corynebacterium

Question 19

What are the three systemic manifestations of diphtheria?

Answer 19

Interference with cardiac conduction

paralyses of palate

kidney failure

also-diphtheric membrane in throat can suffocate

Question 20

What is diphtheria?

Answer 20

Necrotizing upper resp tract infection

Question 21

How does oral TB happen?

Answer 21

Coughing up infected sputum

Someone with an active lung TB →infected sputum→cut open wound in mouth(tongue or tooth extracted socket)

Question 22

What are the most frequent oral locations of oral TB?

Answer 22

Tip and lateral margins of the tongue

hard and soft palate

tooth socket after extraction

Question 23

How does oral TB progress?

Answer 23

clinically can resemble malignancies

red papules→painful soft punched out shallow ulcer

Question 24

What is scrofula ?

Answer 24

TB in the neck involving skin and lymph nodes

Question 25

What is pott's disease?

Answer 25

TB that affects spine and other bones

Question 26

What organism causes TB?

Answer 26

Mycobacterium tuberculosis

Question 27

What are the 5 clinical manifestations of oral candidiasis?

Answer 27

1. Pseudomembranous 2. Atrophic 3. Hypertrophic 4. Angular cheilitis 5. Linear gingival erythema (in HIV Pt)

Question 28

Symptoms of linear gingival erythema?

Answer 28

Oral candidas in HIV

Question 29

Clinical manifestation of pseudomebranous candidiasis?

Answer 29

“thrush” Curd like plaques, can be scraped off, leaving red sores and metallic taste

Question 30

What is atrophic candidiasis?

Answer 30

Thin red epithelium, “denture sore mouth”

Question 31

What are the signs of hyperplastic candidasis

Answer 31

white diffuse or pebbly areas that DO NOT scrape off thickened epithelium mixed with atrophic areas asymptomatic

Question 32

What are the signs of angular chelitis?

Answer 32

cracking at corners of the mouth symptom of oral candidiasis

Question 33

Top 5 species causing oral candidiasis?

Answer 33

**C albicans - most common** C. tropicalis C.glabrata C. parapsilosis C. Krusei