SCLC

Question 1

what are the signs and symptoms

Answer 1

persistent cough
shortness of breath
coughing up blood
chest pain
loss of appetite

Question 1

what are the main treatment options

Answer 1

surgery
chemo
RT

Question 2

what treatment would you offer limited stage T1-4, N0-3

Answer 2

• 4-6 cycles of cisplatin, bidaily. start RT during 1st or 2nd cycle
• if patient cannot tolerate bidaily then 1 times a day
• 45Gy in 30# over 3 weeks
• or offer chemo first followed by sequential RT

Question 3

what treatment would you offer extensive stage T1-4, N0-3, M1a/b

Answer 3

• platinum based chemo if fit enouugh, max 6 cycles
• if partial or complete response the thoracic RT and cranial irradiation
• 25Gy in 10#
• concurrent chemo RT or sequential

Question 4

what are the side effects

Answer 4

fatigue
nausea
hair loss
pain
shortness of breath
sore throat
erythema
weakened immune system
diarrhoea
constipation