Scleroderma

Question 1

What happens in scleroderma?

Answer 1

vascular sclerosis
fibrosis of skin and viscera
injury to vascular endothelium = leakage of proteins into interstitial space
collagen production is not slowed down and gets deposited throughout the body

Question 2

Etiology of scleroderma

Answer 2

unknown (shocker…)
has collagen vascular disease and autoimmune disease characteristics
onset 20-40 years old,