What is prescriptive screening
Comes under what level of prevention
Benefit of self
Secondary
What is prospective screening
Comes under what level of prevention
Benefit of others
Primary+Secondary > Primary
What is mass screening
For large grp individuals ( eg- eye checkup in schools)
High risk screening example
eg - HIV screening in sex workers
What is multipurpose screening and give examples
Screening for > 1 dse at a time
Eg- Antenatal screening
What is multiphasic screening and give example
> 1 test for single dse
DM - FPG, RPG, HbA1c etc
According to model of early detection programs -
Disease onset detection ?
First possible point of dx?
Final critical dx?
Usual time of dx ?
Disease onset detection- changes happen at cellular level
First possible point of dx - changes in cytology, biochemical markers etc
Final critical dx- even after detecting the dse , prognosis is not good
Usual time of dx - presents with sx
What is the best screening time according to model of early detection programs
From first possible point of dx to Final critical dx
what is lead time
lead time - according to model of early detection programs
By screening , how many years earlier we are detecting the dse
From first possible point of dx to Usual time of dx
True positivity of screening test is aka
Sensitivity
True negativity of screening test is aka
Specificity
What is sensitivity
What is the formula
Ability of a test to correctly detect dse
TP/TP+FN
What is specificity
What is the formula
Ability of a test to correctly exclude dse
TN/FP+TN
What is PPV
What is the formula
Presence of dse in test +ve individuals
TP/TP+FP
What is NPV
What is the formula
Absence of dse in test-ve individuals
TN/FN+TN
What is the relationship between dse prevalance and predictive value ( directly or indirectly proportional)
PPV directly proportional to Dse prevalance
NPV indirectly proportional to Dse prevalance
What is the relationship between sensitivity and specificity ( directly or indirectly proportional)
sensitivity indirectly proportional to specificity
What is the relationship between FP and FN ( directly or indirectly proportional)
FP is indirectly proportional to FN
Most important quality of screening test
Sensitivity
Usefulness of screening test depends upon
Sensitivity
High FP cases in a study signify
Test sensitivity is very high
Dse prevalance is low
Predictive value of test depends upon what 3 parameters
If cut off level of a test is shifted to upper side , what does it mean
Highly specific
If cut off level of a test is shifted to lower side , what does it mean
Highly sensitive