SCREENING Flashcards

(47 cards)

1
Q

What is prescriptive screening

Comes under what level of prevention

A

Benefit of self

Secondary

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2
Q

What is prospective screening

Comes under what level of prevention

A

Benefit of others

Primary+Secondary > Primary

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3
Q

What is mass screening

A

For large grp individuals ( eg- eye checkup in schools)

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4
Q

High risk screening example

A

eg - HIV screening in sex workers

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5
Q

What is multipurpose screening and give examples

A

Screening for > 1 dse at a time

Eg- Antenatal screening

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6
Q

What is multiphasic screening and give example

A

> 1 test for single dse

DM - FPG, RPG, HbA1c etc

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7
Q

According to model of early detection programs -

Disease onset detection ?
First possible point of dx?
Final critical dx?
Usual time of dx ?

A

Disease onset detection- changes happen at cellular level

First possible point of dx - changes in cytology, biochemical markers etc

Final critical dx- even after detecting the dse , prognosis is not good

Usual time of dx - presents with sx

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8
Q

What is the best screening time according to model of early detection programs

A

From first possible point of dx to Final critical dx

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9
Q

what is lead time

lead time - according to model of early detection programs

A

By screening , how many years earlier we are detecting the dse

From first possible point of dx to Usual time of dx

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10
Q

True positivity of screening test is aka

A

Sensitivity

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11
Q

True negativity of screening test is aka

A

Specificity

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12
Q

What is sensitivity

What is the formula

A

Ability of a test to correctly detect dse

TP/TP+FN

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13
Q

What is specificity

What is the formula

A

Ability of a test to correctly exclude dse

TN/FP+TN

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14
Q

What is PPV

What is the formula

A

Presence of dse in test +ve individuals

TP/TP+FP

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15
Q

What is NPV

What is the formula

A

Absence of dse in test-ve individuals

TN/FN+TN

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16
Q

What is the relationship between dse prevalance and predictive value ( directly or indirectly proportional)

A

PPV directly proportional to Dse prevalance

NPV indirectly proportional to Dse prevalance

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17
Q

What is the relationship between sensitivity and specificity ( directly or indirectly proportional)

A

sensitivity indirectly proportional to specificity

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18
Q

What is the relationship between FP and FN ( directly or indirectly proportional)

A

FP is indirectly proportional to FN

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19
Q

Most important quality of screening test

20
Q

Usefulness of screening test depends upon

21
Q

High FP cases in a study signify

A

Test sensitivity is very high
Dse prevalance is low

22
Q

Predictive value of test depends upon what 3 parameters

A
  1. Test sensitivity
  2. Test specificity
  3. Dse prevalance
23
Q

If cut off level of a test is shifted to upper side , what does it mean

A

Highly specific

24
Q

If cut off level of a test is shifted to lower side , what does it mean

A

Highly sensitive

25
Cost effective screening test for cancer cervix
VIA > VILI test ( preferred in periphery at PHC/CHC)
26
How much percent of acetic acid is used in VIA
3-5%
27
How do you interpret VIA
Acetowhite patch is suspicious
28
Full form of VILI
Visual inspection with lugols iodine
29
How do you interpret VILI
Turmeric yellow/ Colorless patch is suspicious
30
Best screening test for cancer cervix
Pap smear ( district hospital onwards)
31
Confirmatory test for cancer cervix
Colposcopy guided biopsy
32
Pap smear screening is done how often HPV DNA screening is done how often
Every 3 year Every 5 year
33
Cost effective screening test for breast cancer
Self breast examination
34
Best screening test for breast cancer if >40y
Mammography
35
Best screening test for breast cancer if <40y
MRI>USG
36
Confirmation of breast cancer is done by
Biopsy
37
At what phase of menstrual cycle is self breast exam done and how often
Post menstrual phase and once a month
38
Screening for oral cancer is done by
Bimanual oral exam
39
Screening for colorectal cancer is done by
Occult blood test ---> then proceed for colonoscopy
40
Early detection of which cancer has very good prognosis
Colorectal cancer
41
Screening for neonatal hypothyroidism is done by
neonatal blood taken on day 3-5 for TSH
42
Screening test for DM
RPG
43
Where do we use Kaplan Meier curve
For survival analysis
44
Receiver operator curve is plotted between What is the best curve in that
TP and FP A
45
What is precision/Repetability
same results repeatedly
46
What is Accuracy/Validity
Results near to actual value
47
Where is kappa score ( Cohen's kappa used)
To measure inter rater reliability