SEMIS Flashcards

(132 cards)

1
Q

For a refractometer to obtain accurate levels of protein, its concentrations
in the sample should be:
between 2- 2.5 g/dL
not more than 2.5 g/dL.
greater than 25 g/dL
greater than 2.5 g/dL

A

greater than 2.5 g/dL

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2
Q

A sulfosalicylic acid filtrate
When the Jaffe reaction is employed as a kinetic assay to quantitate serum
creatinine, which of the following is used in the analysis?

A sulfosalicylic acid filtrate
The serum sample is used directly
A Somogyi-Neson filtrate
A Folin-Wu filtrate

A

The serum sample is used directly

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2
Q

The creatinine clearance test is routinely used to assess the glomerular
filtration rate. Given the following information for an average size adult,
calculate the creatinine clearance. Urine creatinine-120 mg/dLPlasma
creatinine-1.2 mg/dLUrine volume for 24 hours-1520 mL *
94.7 mL/min
10.6 mL/min
105.6 mL/min
63.3 ml/min

A

105.6 mL/min

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3
Q

Among the polyanion-divalent cations for HDL-C measurement, this is the
only one that agrees closely with those obtained using analytical or
preparative ultracentrifugation: *
Dextran sulfate –Mg
Heparin-Ca
Sodium phosphotungstate-Mg
Heparin/ Mn++ precipitant

A

Heparin/ Mn++ precipitant

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4
Q

Also known as orosomucoid
prealbumin
Ceruloplasmin
α1-acid glycoprotein
Gc-globulin

A

α1-acid glycoprotein

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5
Q

Patient’s test for serum triglyceride this morning resulted to 220mg/dl.
Later in the afternoon, you remembered you didn’t remove the free
glycerol. How much should have been his result if only you did its
removal? *
80-90 mg/dl
200-210mg/dl
105-110 mg/dl
180-190 mg/dl

A

200-210mg/dl

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6
Q

A patient’s blood has been standing for 2 hours, since the previous Med
Tech on duty has left it beside the centrifuge by negligence. The next
technologist performed the ammonia test which gives a result of 1.336
µg/mL. How much was its initial content and its actual interpretation? *
1.3 µg/mL, increased
1.136 µg/mL, increased
13.0 µg/mL, decreased
1.3036 µg/mL, increased

A

13.0 µg/mL, decreased

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7
Q

Proteins absorb UV light due to the presence of the following EXCEPT: *
phenylalanine
tryptophan
threonine
tyrosine.

A

threonine

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8
Q

This involves the
development of a violet
color from the reaction
of ninhydrin (tri
ketohydrindine hydrate)
and primary amines.
This involves the
development of a violet
color from the reaction
of ninhydrin (tri
ketohydrindine hydrate)
and primary amines.

A

Coomassie
Brilliant
Blue Dye

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9
Q

In this reaction, the
ammonia liberated by
digestion is allowed to
react with alkaline
hypochlorite to form
indophenol blue solution.
The catalyst used is
sodium nitroprusside.
In this reaction, the
ammonia liberated by
digestion is allowed to
react with alkaline
hypochlorite to form
indophenol blue solution.
The catalyst used is
sodium nitroprusside.

A

Berthelot
reaction

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10
Q

This involves reaction of
the liberated ammonium
ions with double iodide
of potassium and
mercury to form
dimercuric ammonium
iodide which is a yellow
to orange brown product.

A

Nesslerization
reaction

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11
Q

This is used to detect
peptides and amino
acids after paper
chromatography.
This is used to detect
peptides and amino
acids after paper
chromatography.

A

Coomassie
Brilliant
Blue Dye

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12
Q

This method of protein
determination is based
on the ability of
phosphotungstomolybdic
acid to oxidize the
phenolic structures of
the amino acids tyrosine,
phenylalanine,
tryptophan and histidine.
This method of protein
determination is based
on the ability of
phosphotungstomolybdic
acid to oxidize the
phenolic structures of
the amino acids tyrosine,
phenylalanine,
tryptophan and histidine

A

Folin
Ciocalteau
Method

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13
Q

Which of the following Amino acids are negatively charged? *
Aspartic Acid
Glutamic Acid
Histidine
Lysine
First 2 choices only
Last 2 choices only
Any of the above

A

First 2 choices only

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14
Q

Most of the fat soluble vitamins are deficient in this condition due to
malabsorption: *
Abetalipoproteinemia
Hypobetalipoproteinemia
Chylomicron retention

A

Abetalipoproteinemia

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15
Q

In determining the Lipid Profile, which procedure / computation is NOT
acceptable: *
VLDL-cholesterol = total cholesterol – infranatant-cholesterol
LDL-cholesterol = infranatant cholesterol – HDL-cholesterol
Determine first TAG, and total cholesterol HDL-cholesterol by chemical means
Total-cholesterol = infranatant cholesterol - TAG

A

Total-cholesterol = infranatant cholesterol - TAG

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16
Q

Deficiency of this protein leads to Wilson’s disease (Hepatolenticular
Degeneration) *
Ceruloplasmin
α1-acid glycoprotein
Gc-globulin
prealbumin

A

Ceruloplasmin

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17
Q

The main endpoint of Alkoxide trans-esterification is the production of this
substance from the liberation of glycerol: *
lipoproteins
NADH
H2O2
Formaldehyde

A

Formaldehyde

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18
Q

Cystinuria

A

reabsorption
of positively
charged
amino acids

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19
Q

Glutaric
acidemia type 2

A

proteins
fats
metabolism

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20
Q

Alkaptonuria

A

tyrosine &
phenylalanine

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21
Q

Type II
citrullinemia

A

urea
cycle

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22
Q

The following statements are true regarding Uric acid determination
EXCEPT: *
Ethanol ingestion frequently increases the plasma concentration

It is readily oxidized to allantoin

It may be oxidized by alkaline
phosphotungstate

Using the enzyme catalase remains the most specific method

A

Using the enzyme catalase remains the most specific method

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22
Q

Homocystinuria

A

methionine

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23
A____ level of free haptoglobin suggests hemoglobinuria or hemolysis: * decrease in urine decrease in serum increase in urine increase in serum
decrease in serum
24
Reference values for different proteins: * albumin (3.2-4.5 g/dL), globulin(2.3-3.5 g/dL), and fibrinogen(0.2-0.4 g/dL) albumin (4.2-4.5 g/dL), globulin(3.2-3.5 g/dL), and fibrinogen(0.2-0.4 g/dL) albumin (2.3-3.5 g/dL), globulin(3.2-4.5 g/dL), and fibrinogen(0.2-0.4 g/dL) albumin (3.2-4.5 g/dL), globulin(2.3-3.5 g/dL), and fibrinogen(0.4-0.8 g/dL)
albumin (3.2-4.5 g/dL), globulin(2.3-3.5 g/dL), and fibrinogen(0.2-0.4 g/dL)
25
Which enzymatic reactions has 4-P-benzoquinonemonoiminophenazone as its end-product? * Winartasaputra Nagele- trinder Baculo-David Megraw
Nagele- trinder
26
Reference interval for serum creatinine concentration in children: * 0.6-1.5mg/dL 0.2-0.6mg/dL 0.3mg -1.0mg/dL 1.0 -2.0g/dL
0.3mg -1.0mg/dL
27
The following refer to Kjeldahl digestion procedure EXCEPT: * It uses a catalyst like copper sulfate Oxidation involves a strong sulfuric acid It is an oxidation process by heating at 70 0C It liberates the nitrogen content
It is an oxidation process by heating at 70 0C
28
Risks from high protein diet include the following EXCEPT: * elevates Uric Acid increased level of ammonia elevates Calcium stress on kidneys
elevates Calcium
29
GOUT comprises a heterogenous group of disorders characterized by the following EXCEPT: * deposition of monosodium urate crystals throughout the body attacks of acute inflammatory arthritis hyperuricemia gallbladder stones
gallbladder stones
30
This step involves precipitation of free cholesterol to remove the errors due to non specific chromogen interference present in the sample. * Saponification Purification Color development Extraction
Purification
31
A potent stimulant for the contraction of the gallbladder. * chymotrypsin secretin pepsinogen cholecystokinin
cholecystokinin
32
Quantitation of serum _____is a marker for nutritional status: * Gc-globulin α1-acid glycoprotein Ceruloplasmin prealbumin
prealbumin
33
Mr John Ford, 60y.o, came for a general check-up yesterday with the following laboratory results: TG = 200mg/dl; Total Cholesterol = 200mg/dl; HDL = 80mg/dl; What is his current risk for the development of coronary heart diseases? * low no relation High variable
low
34
The following are correct regarding Lipid Measurements EXCEPT: * a decrease of 10% with triglyceride levels, with a sudden change in patient’s position. Cholesterol esters are higher in the winter Ideal fasting: 12 –14 hours should be made no sooner than 8 weeks after any form of trauma or acute bacterial or viral infection
a decrease of 10% with triglyceride levels, with a sudden change in patient’s position.
35
A balikbayan, 35y.o, came for a general check-up yesterday with the following laboratory results: BUN = 15mg/dl; Creatinine before heating = 1.0mg/dl; Creatinine after heating = 2.0mg/dl. How much is his serum Creatine value? 0.2mg/dl 0.6mg/dl 1.0mg/dl 1.4mg/dl
1.0mg/dl
36
Lipoprotein contents of Infranatant after Ultracentrifugation at various densities. 1.210
proteins
37
Lipoprotein contents of Infranatant after Ultracentrifugation at various densities. 1.006kg/L
HDL, proteins
38
Lipoprotein contents of Infranatant after Ultracentrifugation at various densities. 1.063 kg/L
LDL, HDL, protein
39
The lipoproteins are measured in terms of total lipoprotein mass using the following which detects the concentration dependent changes in the refractive indices of the lipoproteins: * Schlteren optics Fiber optics Svedberg units Standard International Units
Schlteren optics
40
Lesch-Nyhan syndrome is an X-linked disorder due to the complete deficiency of _______ Uricase xanthine oxidase hypoxanthine phosphoribosyltransferase catalase
hypoxanthine phosphoribosyltransferase
41
Cause of Azotemia/Low Urea: Liver Disease
Decreased Urea Production
42
Cause of Azotemia/Low Urea: Renal artery severe atherosclerosis
Prerenal azotemia
43
Cause of Azotemia/Low Urea: * Stones clogging ureters
Postrenal azotemia
44
The following refer to the CORRECT concentration of each of the major end products of nitrogen metabolism EXCEPT: * urea (56%) Creatinine(4.5%), ammonium(2.8%) uric acid(1.7%)
urea (56%)
45
To quantitate the creatine concentration in a urine specimen, it is necessary to treat the urine in what manner? * Adjusting it to an acid pH and heating at 100oC Adjusting it to an alkaline pH and heating at 37oC Adjusting it to an acid pH and heating at 37oC Adjusting it to an acid pH and heating at 56oC
Adjusting it to an acid pH and heating at 100oC
46
The following statements are true about Non-protein Nitrogenous Substances EXCEPT: * NPN concentration of whole blood is 50% greater than that of the plasma The total plasma nitrogen concentration is between 250-400mg/dl They are products of catabolism of proteins, amino & nucleic acids. Urea is the major NPN in the plasma
NPN concentration of whole blood is 50% greater than that of the plasma
47
In gel electrophoresis, match the cholesterol with the proteins they travel with:LDL
β-globulins
48
In gel electrophoresis, match the cholesterol with the proteins they travel with:VLDL
pre-β
49
In gel electrophoresis, match the cholesterol with the proteins they travel with:chylomicrons
remain at origin
50
In gel electrophoresis, match the cholesterol with the proteins they travel with:HDL
α-globulins
51
Homogenous assays for LDL-C can provide clinically useful results when triglycerides are * >400 mg/dL within normal level <400 mg/dL >200 mg/dL
>400 mg/dL
52
Patient Maria, 40y.o, came for a general check-up yesterday with the following laboratory results: BUN = 15mg/dl; Creatinine before heating = 1.0mg/dl; Creatinine after heating = 2.0mg/dl. Evaluate his status as to his B/C ratio: * Renal azotemia normal kidney function Postrenal azotemia Prerenal azotemia
normal kidney function
53
Describe these Aminoacidurias according to the Amino Acid/ Protein Affected: Glutaric acidemia type 2
hypoglycemia & sweaty
54
Describe these Aminoacidurias according to the Amino Acid/ Protein Affected:Alkaptonuria
homogentisic acid (black urine)
55
Describe these Aminoacidurias according to the Amino Acid/ Protein Affected:Cystinuria
cystine crystals in urine
56
When the transferrin level is high, it refers to the following EXCEPT: * iron saturation is high increased iron binding capacity decrease in iron levels there is iron deficiency
decrease in iron levels
57
In the Berthelot reaction, a blue-indophenol compound is formed that is proportional to the quantity of urea in the specimen being analyzed. Falsely elevated urea values will occur with this procedure when the reaction mixture is contaminated by * Ammonia Protein Bacteria Glucose
Ammonia
58
The following are the affected fat soluble vitamins due to malabsorption in the problem of Premature degradation of apoB EXCEPT. * Vitamin D Vitamin E Vitamin A Vitamin K
Vitamin D
59
Frozen samples cannot be used in this method of Lipid Measurement: * Chemical Method Enzymatic Method Electrophoresis Ultracentrifugation
Ultracentrifugation
60
Describe these Aminoacidurias according to the Enzyme Defect:Alkaptonuria
homogentis 1,2 dioxygen
61
Describe these Aminoacidurias according to the Enzyme Defect:Glutaric acidemia type 2
flavoprotein dehydrogenase
62
Describe these Aminoacidurias according to the Enzyme Defect:Cystinuria
SLC3A1 & SLC7A9 mutation
63
Describe these Aminoacidurias according to the Enzyme Defect:Type I citrullinemia
argininosuccinate synthetase
64
Describe these Aminoacidurias according to the Enzyme Defect:Hartnup disease
SLC6A19 gene
65
DIfferentiate these abnormal lipoproteins: lipoprotein ß-VLDL
floating ß-lipoprotein
66
DIfferentiate these abnormal lipoproteins: Lp(a) lipoprotein
sinking pre-ß –lipoprotein
67
To correct for interfering nucleic acids, the protein concentration may be calculated using this formula: * Protein(mg/mL) = (15.5 x A280) – (0. 67 x A260) Protein(mg/mL) = (0.76 x A280) – (1.55 x A260) Protein(mg/mL) = (1.55 x A280) – (0.76 x A260) Protein(mg/mL) = (1.55 x A260) – (0.76 x A280)
Protein(mg/mL) = (15.5 x A280) – (0. 67 x A260)
68
Which of the following amino acids are glucogenic? * tyrosine cysteine leucine lysine alanine 1st,2nd, & 5th choices only 3rd & 4th choices only All of the above
1st,2nd, & 5th choices only
69
A patient’s blood has the following results: Total protein= 3.3g/dL; Albumin= 1.1g/dL Compute for his A:G ratio: * 1.3 3:1. 2:1 1:2
3:1.
70
In zonal electrophoresis, the α-globulins are further resolved into α1 and α2 fractions. at this pH * 7.6 6.8 8.6 6.7
8.6
71
The plasma total proteins are within the range of: * 50-68 g/L 80-90 g/L 6.0-7.8 g/dL FIRST 2 choices only last 2 choices only Any of the above
6.0-7.8 g/dL
72
A patient was extracted at 6:00AM for Lipid Profile, with the following results: TAG = 200mg/dL; Total Cholesterol = 220mg/dL; HDL cholesterol = 35mg/dL; Infranatant cholesterol = 140mg/dL. If the process includes ultracentrifugation, compute for the patient’s LDL & VLDL. * 175mg/dL LDL, 215mg/dL VLDL 105mg/dL LDL, 80mg/dL VLDL 80mg/dL LDL, 15mg/dL VLDL 40mg/dL LDL, 185mg/dL VLDL
105mg/dL LDL, 80mg/dL VLDL
73
This colorimetric development for cholesterol assay produces red to reddish violet cholestadienyl disulfonic acid. * Salkowski of zak reaction Nagele- trinder reaction Leibermann-burchardt (LB) reaction Baculo-David (NADH consumption method)
Salkowski of zak reaction
74
Expected Laboratory Results: Kidney diseases
Low B/C ratio with low urea & higher creatinine
75
Expected Laboratory Results: Renal artery severe atherosclerosis
high B/C ratio with normal creatinine
76
Expected Laboratory Results: Stones clogging ureters
high B/C ratio with elevated creatinine
77
Salting-out process of globulins means: * precipitation in Rochelle salt environment precipitation with 22-26% sodium sulfate oxidation with copper sulfate floatation method by ultracentrifugation
precipitation with 22-26% sodium sulfate
78
This does NOT participate in the excretion of Urea: * kidneys GI tract Liver skin
Liver
79
The order of elution in Cation-exchange chromatography * α2-globulins, albumin, β-globulins, and α1-globulins. β-globulins, α2-globulins, α1-globulins, and albumin. albumin, α1-globulins, α2-globulins, and β-globulins α1-globulins α2-globulins , β-globulins, and albumin.
albumin, α1-globulins, α2-globulins, and β-globulins
80
These Dyslipidemia present with high cholesterol, elevated LDL-C, and normal triglycerides, EXCEPT: * Diabetic dyslipidemia Sitosterolemia Family defective apoB Familial hypercholesterolemia
Diabetic dyslipidemia
81
The Biuret reagent contains the following EXCEPT: * sodium hydroxide to provide alkalinity potassium hydroxide to keep the copper ions in the cupric state copper sulfate for the biuret formation Rochelle salt environment
potassium hydroxide to keep the copper ions in the cupric state
82
In anion-exchange chromatography, the order of elution is usually: * β-globulins, α2-globulins, α1-globulins, and albumin. α2-globulins, albumin, β-globulins, and α1-globulins. albumin, α1-globulins, α2-globulins, and β-globulins. α1-globulins α2-globulins , β-globulins, and albumin.
albumin, α1-globulins, α2-globulins, and β-globulins.
83
Ammonia is formed as a product of transmination and deamination of amino acids. To maintain the acid-base balance, it is necessary that the blood ammonia levels be kept within narrows limits. This is accomplished primarily by which of the following? * Synthesis of urea from ammonia Synthesis of glutamine from ammonia Excretion of ammonia in the urine Excretion of ammonia in the bile
Synthesis of urea from ammonia
84
Juan de la Cruz, 50y.o, came for a general check-up yesterday with the following laboratory results: TG = 200mg/dl; Total Cholesterol = 200mg/dl; HDL = 80mg/dl; How much are the patient’s LDL & VLDL by Friedewald computation? * LDL = 80mg; VLDL = 40mg/dl LDL = 40mg; VLDL = 80mg/dl LDL = 89.2mg; VLDL = 30.8mg/dl LDL = 30.8mg; VLDL = 89.2mg/dl
LDL = 80mg; VLDL = 40mg/dl
85
Xanthomata are common in these condition/s: * Familial hypercholesterolemia 1st & 3rd choice only Familial dysbetalipoproteinemia Familial hypo-α-lipoproteinemia All of the above
Familial hypercholesterolemia
86
A partial deficiency of this substance could result to “Fish-eye disease”: * Lipoprotein lipase (LPL) Cholesterol ester transfer protein (CETP) LDL receptor (LDLR) Lecithin:Cholesterol Acyltransferase (LCAT)
Lecithin:Cholesterol Acyltransferase (LCAT)
87
Reversal in the A/G ratio may be seen in the following conditions EXCEPT: * lactose intolerance infectious diseases liver diseases multiple myeloma
lactose intolerance
88
Lipoprotein composition of Supranatant after Ultracentrifugation at various densities: 1.210
CM, VLDL, LDL, HDL
89
Lipoprotein composition of Supranatant after Ultracentrifugation at various densities: 1.006kg/L
CM, VDL
90
Lipoprotein composition of Supranatant after Ultracentrifugation at various densities: 1.063 kg/L
CM, VLDL, LDL
91
In the Jaff reaction, the creatinine is treated with this solution to yield a bright orange-red complex: * diacetyl monoxime alkaline picrate 4-aminophenazone nitroprusside
alkaline picrate
92
The tests on which of these Lipids may be done on a non-fasting specimen? A or C Total cholesterol HDL-C LDL-C
A or C
93
Protein Electrophoresis: Gc-globulin
It migrates as an α1 globulin
94
Protein Electrophoresis:Haptoglobin
migrates in the α2-region
95
Protein Electrophoresis:Fibrinogen
migrates between the β and y fractions
96
Protein Electrophoresis: β-lipoprotein
migrates with feathery trailing edge
97
Protein Electrophoresis:Complement
travels with the β globulins
98
The following statements refer to the interference by bilirubin in cholesterol determination EXCEPT: * It may also interfere directly with chemical methods It could react with an intermediate in the peroxidase reaction. It is significant only at concentration exceeding 5 mg/dL It has been reported to decrease cholesterol values by 5-15%.
It may also interfere directly with chemical methods
99
It is the principal source of renal ammoniagenesis. * Glutamine Histidine Methionine Cysteine
Glutamine
100
The following refer to the most popular method used to measure Urea EXCEPT: * It uses the coupled enzymatic reaction It quantitates the NH4+ produced from the indirect procedure mediated by Urease It employs the Berthelot reaction It uses the spectrophotometer
It employs the Berthelot reaction
101
Which of the following statement can be associated with the enzymatic assay of ammonia? * Increase in absorbance monitored at 340 nm NAD required as a cofactor Reaction catalyzed by glutamate dehydrogenase 2nd & 3rd choices only All choised Other:
Reaction catalyzed by glutamate dehydrogenase
102
Triglycerides Conversion from mg/dL to mmol/L, multiply result by: * 88.6 0.01129 38.7. 0.02586
0.01129
103
Normal Plasma Concentration: C-reactive protein (adult)
479 1340ng/mL
104
Normal Plasma Concentration: Fibrinogen
0.2-0.4 g/Dl
105
Normal Plasma Concentration: Hemopexin
50-120mg/dL
106
Normal Plasma Concentration: Transferrin
200-400 mg/dL
107
Normal Plasma Concentration: Ceruloplasmin
20-40mg/dL
108
. The following refer to the most popular method used to measure Urea EXCEPT: * It uses the spectrophotometer It quantitates the NH4+ produced from the indirect procedure mediated by Urease It employs the Berthelot reaction It uses the coupled enzymatic reaction
It employs the Berthelot reaction
109
A pathognomonic feature of this condition is “a broad electrophoretic band between VLDL and LDL kown as ‘abnormally migrating beta lipoprotein’ or ß VLDL: * Familial combined hyperlipidemia Hepatic lipase deficiency Familial hypertriglyceridemia Dysbetalipoproteinemia
Dysbetalipoproteinemia
110
In the ultraviolet procedure for quantitating uric acid, what does the reaction between uric acid and uricase cause? * A destruction of uric acid The formation of allantoin An increase in absorbance 1ST & 3RD choices only
1ST & 3RD choices only
111
Formula for correcting LDL-C for the contribution of Lp(a) cholesterol. * LDL-C= TC-[HDL-C]- Plasma TG/5 - 0.3 x [Lp(a) mass)] LDL-C= TC-[HDL-C]- Plasma TG- 0.3 x [Lp(a) mass)]/5 LDL-C= TC-[HDL-C]- Plasma TG/5 + 0.3 x [Lp(a) mass)]
LDL-C= TC-[HDL-C]- Plasma TG/5 - 0.3 x [Lp(a) mass)]
112
Stains for proteins: Period Acid Schiff
glycoproteins
113
Stains for proteins:Coomassie brilliant blue
detect peptides and amino acids
114
Stains for proteins:Sudan black
lipoproteins
115
In protein metabolism which of the following enzymes are involved in the pancreatic phase of Protein digestion? * pepsin elastase carboxypeptidase dipeptidases gastrin ___ 3 points detect peptides and amino acids glycoproteins lipoproteins aminopoptidases E) tryptophan 1st & 5th choices only 2nd & 3rd choices only 4th & 6th choices only All of the above
2nd & 3rd choices only
116
The following are essential amino acids: * phenylalanine threonine histidine serine methionine tryptophan All except 6th choice All except 4th choice All of the above
All except 4th choice
117
These proteins are absorbed without being digested first: * allergens 1st & 3rd choices only Immunoglobulin A (1gA) animal heme
Immunoglobulin A (1gA)
118
Fluffy’ triglyceride-rich VLDL particles are seen in: * Lipoprotein Lipase deficiency Familial hypertriglyceridemia ApoC III excess ApoC-II deficiency
Familial hypertriglyceridemia
119
This is the standard & reference, non-enzymatic method used by Centers for Disease Control for Cholesterol measurement: * Carr-Drekter method Abell-kendall method Schoenheimer- Sperry Zlatkis-Zak-Boyle
Abell-kendall method
120
Standing Plasma Test gives the following positive result for chylomicrons: * opalescent top layer creamy infranatant creamy top layer opalescence or turbidity to the infranatant.
creamy top layer
121
Which of the following statement can be associated with the enzymatic assay of ammonia? * Increase in absorbance monitored at 340 nm Reaction catalyzed by glutamate dehydrogenase NAD required as a cofactor 1st 2 choices only Last 2 choices only Any of the above
Reaction catalyzed by glutamate dehydrogenase
122
Corneal opacification can occur in patients with this dyslipidemia: * 1st & 3rd choice only Familial hypoalphalipoproteinemia ApoA-I variants All of the above ApoA-1 deficiency and ApoC-III deficiency
ApoA-1 deficiency and ApoC-III deficiency
123
This condition is also known as “Tangier’s disease”: * Familial dysbetalipoproteinemia Familial hypercholesterolemia Familial hypo-α-lipoproteinemia Familial combined hyperlipidemia
Familial hypo-α-lipoproteinemia
124
The following can interfere with enzymatic measurements for blood cholesterol, EXCEPT: * high doses of ascorbic acid icteric specimen free glycerol plant sterols in the circulation of patients with ß sitosterolemia.
free glycerol
125
An admitted patient undergoing dialysis has a Blood Urea Nitrogen of 80mg/dL How would you expressed this in Urea mmol/L? * 28.56mmol/L 2.8 – 7.1mmol/L 35.7mmol/L 71.4mmol/L
28.56mmol/L
126
Major Apolipoprotein of the Lipoprotein particles. (Choices may be used more than once.) Chylomicrons
Apo B-48
127
Major Apolipoprotein of the Lipoprotein particles. (Choices may be used more than once.) HDL
Apo B-100
128
Major Apolipoprotein of the Lipoprotein particles. (Choices may be used more than once.) LDL
Apo B-100
129
Major Apolipoprotein of the Lipoprotein particles. (Choices may be used more than once.) VLDL
Apo A
130
Desirable total blood cholesterol level: * <250mg/dL <240mg/dL < 200mg /dL < 100mg/dL
< 200mg /dL