1
Q
What condition is induced by spironolactone?
A
Type 4 RTA
RTA stands for Renal Tubular Acidosis.
2
Q
What is the effect of MR antagonist on aldosterone action?
A
Causes hyperkalaemic acidosis
3
Q
What should be checked after 7 days of spironolactone treatment?
A
K*/HCO3 levels
4
Q
What action should be taken if K* levels exceed 5.5 mmol L?
A
Reduce dose or swap to eplerenone
5
Q
What can offset the rise in K* levels?
A
Loop diuretic by increasing distal Na* delivery
6
Q
What dietary advice is given to patients on spironolactone?
A
Advise low-K* diet and avoid salt substitutes
7
Q
What should be added if HCO3 levels fall below 18 mmol L?
A
Add NaHCO3
8
Q
Fill in the blank: MR antagonist causes _______ acidosis.
A
hyperkalaemic
EDIC
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