Severe symptoms
throughout the day
Severe nighttime awakenings
ages 0-4: > 1x/week
ages 5-11 and adults: often 7x/week
Severe SABA use
several times per day
Interference with normal activity
extremely limited
Severe lung function
ages 5-11: FEV1 < 60% FVC1 <75%
adults: FEV1 < 60% FVC1 reduced > 5%