Acute syndrome of organ and system dysfunction precipitated by failure of circulation to meet the needs of metabolically active tissues?
Shock
What is the primary physiologic dysfunction of shock?
Impaired cellular function due to decreased nutritional blood flow.
What is going on during shock?
Reduced oxygen and nutrient supply > anaerobic metabolism > acid production (lactic and pyruvic) > decreased ATP and reduced energy
What enzyme is responsible for destroying the cell and eating its cellular contents when the pH decreases?
Proteolytic enzyme
Is cellular change reversible once membrane integrity is lost?
NO!
What are some types of shock?