Internal Medicine > SIADH > Flashcards

SIADH Flashcards

(6 cards)

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1
Q

Define

A
  1. Inappropriate secretion from posterior pituitary

2. Ectopic production

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2
Q

Pathophysiology

A

+ADH->excessive reabsorption of water in distal neprhon, not inhibited by hyponatremia.
Plasma osmolality falls

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3
Q

Calculate plasma osmolality

A

2 X sodium + urea + glucose

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4
Q

Diagnosis made

A

Comparison of plasma oxmolality and urine->urine osmolarity inappropriately elevated

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5
Q

Drug mechanism

A
  1. +ADH
  2. Potentiate effects
  3. Unknown mechanism
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6
Q

Causes

A 
1. Drugs
AntiD, antipsychotics
Chemotherapy
Omeprazole
2. Post-operative stress
3. CNS
Infections
Stroke
Trauma
Neurosurgery
4. Pulmonary
Pneumonia
TB, empyema
Status asthmaticus
5. Malignant
Neoplasm
Lymphoma
Leukemia
Mesothelium
Ewings sarcoma
6. Psychoses
7. Vasopressin or oxytocin
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