Sickle Cell

Question 1

labs of acute chest syndrome?

Answer 1

normocytic normochromic anemia, inc WBC, inc plt, inc retic count, inc indirect bili

Question 2

cause of acute chest sydnrome?

Answer 2

underlying infection

Question 3

transfusion goal in acute chest syndrome?

Answer 3

dont go above 11, hgb goal <9

Question 4

smear with sickle cell?

Answer 4

sickles, target cells, howell jolly(functional asplenia

Question 5

hgb electropharesis with sickle cell trait?

Answer 5

HbA>Hbs

Question 6

sx with sickle cell trait?

Answer 6

only if significant hypoxia or dehydration

Question 7

beta thalassemia hgb electropharesis?

Answer 7

HgbE- F and A2

Question 8

increased LFT, hepatomegaly in SCD concern? tx?

Answer 8

hepatic sequestration/red cell exchange

Question 9

hepatic concerns in SCD?

Answer 9

budd chiari because hypercoagulable and hepatic sequestration