Licence
Indicated treatment of chronic hyperuricaemia in conditions where urate deposition has already occurred (including history or presence of tophus and or gouty arthritis) in adults
What are the dose adjustments for elderly and renal impaired pts taking Febuxostat?
None
Febuxostat is mostly metabolised in the…….?
Liver
Febuxostat is a………..
Non purine selective inhibitor of xanthine oxidase
How long does Febuxostat take to reach a steady state?
Within first week of treatment
What are the licensed doses of Febuxostat?
How much does it cost
80mg od.
120mg od.
£24.36
What are drug to drug interaction dr’s should be aware of with Febuxostat
Not recommended for use with mercaptopurine or azathioprine
Monitor theophylline levels (XO inhibition may increase levels)
No dose adj for NSAIDS WARFARIN COLCHICINE ANTACIDS