SMPC Flashcards

(7 cards)

0
Q

Licence

A

Indicated treatment of chronic hyperuricaemia in conditions where urate deposition has already occurred (including history or presence of tophus and or gouty arthritis) in adults

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1
Q

What are the dose adjustments for elderly and renal impaired pts taking Febuxostat?

A

None

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2
Q

Febuxostat is mostly metabolised in the…….?

A

Liver

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3
Q

Febuxostat is a………..

A

Non purine selective inhibitor of xanthine oxidase

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4
Q

How long does Febuxostat take to reach a steady state?

A

Within first week of treatment

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5
Q

What are the licensed doses of Febuxostat?

How much does it cost

A

80mg od.
120mg od.

£24.36

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6
Q

What are drug to drug interaction dr’s should be aware of with Febuxostat

A

Not recommended for use with mercaptopurine or azathioprine
Monitor theophylline levels (XO inhibition may increase levels)

No dose adj for NSAIDS WARFARIN COLCHICINE ANTACIDS

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