1
Q
What are some examples of SNRI?
A
Venlafaxine
Desvenlafaxine
2
Q
What is the toxic risk dose for venlafaxine?
A
> 8 grams
3
Q
What are the toxidromes associated with SNRI toxicity?
A
Serotonin toxicity
- Fever, Mental state changes, Autonomic instability, Neuromuscular abnormalities
Noradrenergic toxicity
- Acute catecholamine induced cardiomyopathy
- Progressive tachycardia
- Ventricular dysrhythmias
- Cardiogenic shock
- Death
4
Q
How do you manage noradrenergic toxicity?
A
Assessment with echocardiogram to determine
- High dose insulin therapy
- ECMO
Toxicology
flashcards
Decks in class (5)
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