Top 3 leading global causes of death by sex
Male
Females
What are the leading risk factors for death?
HTN Tobacco High cholesterol Underweight Unsafe Sex High BMI Physical Activity Alcohol
Stages 1 of Demographic Transition and effects on population pyramids
Poor development
Stage 2 and 3 of Demographic Transition and effect on population pyramid
Development and improvement in care
Stage 4 of demographic transition and effect on population pyramid
High income countries
Population Pyramid changes through stages of demographic transition
From High to low mortality (1-4) leads to a shift from a ‘pyramid’ with a young population base to the ‘diamond’ shape with a shrinking base and a growing top (Ageing population)
Stages in the epidemiological transition for cardiovascular risk
Increasing levels of acculturation, urbanisation, and affluence are initially associated with an increase in cardiovascular disease due to HTN and Atherosclerosis via increased smoking and fat and salt intake.
Hypertension begins to plateau and then decrease at high urbanisation and affluence
Atherosclerosis continues to increase.
Define Primordial Prevention
Define Primary Prevention
Reduction of incidence of disease among healthy individuals by:
Define Secondary Prevention
Early detection of pre-clinical disease (screening)
Treatment to prevent progression or recurrence (chemotherapy)
Define Tertiary Prevention
Treatment of established disease to prevent complications or relieve distress (Asthma - Steroids)
What is the population strategy for reducing CVD?
Aims to reduce the risk factor of interest (e.g BP) in everyone in the population, on the knowledge that the risk of having CVD is directly related to the level of the risk factor and that a small reduction in the level of the risk factor will reduce the risk in everyone.
Implementation leads to a reduction in the proportion of people in the upper end of the distribution (diseased) –> reduction in incidence and prevalence
What is the High Risk strategy for reducing CVD?
Also known as the ‘medical approach’
Aims to treat those with a defined disease status (e.g HTN or DM)
Whilst these people have the highest risk of developing CVD, there are not many in the population, so the impact of the burden of CVD is small.
The high risk strategy will not reduce the ‘ incidence’ of disease since it will not address the causes but will deal with the consequences and manifestations.
Pros and Cons of the population strategy of disease reduction
Pros
Cons
Pros and Cons of the high risk strategy of disease reduction
Pros
-Extension of traditional clinical approach
Cons
Drivers reducing mortality from CVD in England and Wales
Improvement in Pharmacological Therapy - Statins - Anti-hypertensives Increase in invasive procedures - Angioplasty - PTCA Therapy - MECC Primary Prevention
What is the double burden of communicable and chronic disease in low income countries
A high death rate occurring due to the presence of both communicable diseases and chronic disease, both of which are poorly controlled.
Why is CVD a problem?
Rising toll of non-communicable diseases
Growing economic burden
Spreading to the developing world
Outline the three connections of CVD drivers.
Dietary Connection
Physical Activity Connection
- Rise of cars
Rise of obesity (and underweight)
Cultural Connection
How has diet changed with nutritional transition?
More meat, fat, sugar, salt, soft drinks, energy dense food.
Less/not enough staples, fruit and vegetables, fibre, water
Briefly outline WHO’s Global Action Plan for non-communicable disease
Reduce premature mortality from CVD, cancer, DM, chronic respiratory disease (25%)
Reduce harmful use of alcohol (10%)
Increase exercise
Reduce mean population intake of salt/sodium (30%)
Reduce tobacco use in persons aged 15+ (30%)
Reduction in prevalence of raised BP or contain prevalence of raised BP (25%)
Halt the rise in DM and obesity
Increase eligibility of people to drug therapy and counselling to prevent MI and stroke
80% availability of affordable basic tech and medicines.
Outline the 4 domains to reduce population salt intake
Communication - Public awareness campaigns - Food industry -Media -Health professionals Reformulation - Setting targets - Food labelling - Industry engagement - motivation -customer awareness - corporate responsibility - voluntary vs regulatory Monitoring - Population salt intake via urinary sodium and dietary surveys - Reformulation progress via salt content of food checks - Effectiveness of campaigns by measuring awareness and attitudes and behaviour changes Research - Epidemiology - nutrition - public health - food tech - behavioural - evaluation - policy
How effective was the 8 year national campaign to reduce salt intake?
Reduction in IHD, stroke, and BP
Define Surveillance
Information for Action
The ongoing systematic collection, collation, analysis, and interpretation of data, and the dissemination of information (to those who need to know) in order that action may be taken.