Softgels

Question 1

What are soft gels?

Answer 1

Consist of a liquid or a semi-solid matrix in a one-piece outer gelatine shell

Question 2

Desirable characteristics

Answer 2

Elegant appearance
Easy to swallow
Masks odour
Improved bioavailability
Longer shelf-life
Shell ruptures rapidly and fill liquid released rapidly
Rapid therapeutic action
Safe
Efficient manufacturing process and affordable cost

Question 3

Gel manufacturing process

Answer 3

Gelatin, Water and Placticizer is heated
Melts
Add colours to form coloured gel

Question 4

Advantage of soft gels

Answer 4

Improved drug absorption
Improved bioavailability
Improved plasma variability
Safety for potent and cytotoxic drugs
Oils and low melting point drugs
Dose uniformity of low-dose drugs
Product stability