Solid Tumor Marker Quiz Flashcards by Jackie Marquez

Q

Alveolar rhabdomyosarcoma (ARMS)

A

PAX-FKHR, translocation rearrangement

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Q

Ewing Sarcoma

A

t(11;22) EWS-FLI-1
translocation, rearrangement

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Q

Gastrointestinal stromal tumors (GISTs)

A

KIT
gene amplification/ over expression

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Q

Lung adenocarcinoma

A

ROS1
translocation, rearrangement

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Q

Neuroblastoma

A

MYCN
gene amplification/ over expression

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Q

Non-small cell lung cancer 1

A

EGFR
L858R mutation

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Q

Non small cell lung cancer 2

A

ALK
translocation rearrangement

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Q

retinoblastoma

A

RB1
loss by deletion, silencing

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Q

Synovial Sarcoma

A

t(X;18)
translocation/rearrangement

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Q

Thyroid papillary carcinomas

A

RET
translocation rearrangement.

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