when is SOS response activated
if DNA is heavily damaged by mutagenic agents
SOS response involves what
Recombination, repair and replication
what polymerase replicates DNA in damaged regions
V but cannot be replicated accurately
SOS response does what overall
eliminates gaps but increases the frequency of replication errors
In the absence of DNA damage, what happens (lexA)
LexA binds to DNA regions that regulate transcription of SOS response genes and keeps their expression levels low
When their is DNA damage, what happens (RecA)
RecA binds to single stranded regions of damaged DNA
RecA does what in terms of LecA
stimulates LexA to inactivate itself as LexA controls SOS expression