Spectrum by Pathogen

Question 1

S. aureus - MSSA

Answer 1

Cloxacillin 
Cefazolin 
\+/- 2nd/3rd gen cephalosporins 
BL/BLase inhibitors (Amoxi/Clav, Pip/Tazo, Tic/Clav) 
Carbapenems 
Macrolides (mild infections)

Vancomycin 
Clindamycin (mild infections) 
SMX-TMP 
Linezolid 
Daptomycin 
Tigecyclin

Question 2

S. aureus - MRSA

Answer 2

Vancomycin 
Clindamycin (mild infections) 
SMX-TMP 
Linezolid 
Daptomycin 
Tigecyclin

Question 3

Strep pneumoniae

Answer 3

Penicillins (except Cloxacillin) 
Cephalospoins (except Ceftazidime) 
Levofloxacin, Moxifloxacin (not cipro/nor) 
Macrolides (some resistance) 
Vancomycin 
Linezolid 
Daptomycin 
Tetracyclines 
Tigecycline 
Carbapenems

Question 4

Enterococcus

Answer 4

Penicillins (except Cloxacillin) 
Vancomycin 
Linezolid 
Tigecycline 
Daptomycin

Question 5

Atypicals

Answer 5

Macrolides
Fluoroquinolones
Tetracyclines

Question 6

PEcK

Answer 6

\+/- Ampicillin/Amoxicillin (except Klebsiella) 
BL/BLase inhibitors (Amoxi/Clav, Pip/Tazo, Tic/Clav) 
Cephalosporins 
Aminoglycosides 
Fluoroquinolones 
SMX-TMP 
Carbapenems 
Tigecycline (except Proteus)

Question 7

H. influenzae

Answer 7

Ampicillin/Amoxicillin (20% resistance) 
BL/BLase inhibitors 
2nd gen Cephalosporins and higher 
Clarithromycin, Azithromycin 
Fluoroquinolones 
SMX-TMP 
Carbapenems

Question 8

SICE/SACE

Answer 8

Fluoroquinolones
Carbapenems
SMX-TMP
Aminoglycosides
3rd gen Cephalosporins, Pip, Tic +/- BLase inhibitors (NOT recommended because resistance induced!!!)
Tigecycline (except Indole positive proteus)

Question 9

P. aeruginosa

Answer 9

Aminoglycosides 
Pip, Tic +/- BLase inhibitors 
Ceftazidime 
Cefepime 
Ciprofloxacin 
Carbapenems (except ertapenem)

Question 10

Anaerobes

Answer 10

Metronidazole 
Clindamycin 
Amoxi/Clav, Pip/Tazo, Tic/Clav 
Cefoxitin (some resistance) 
Carbapenems 
Tigecycline 
Moxifloxacin (Some resistance)