stages of cell cycle
G1/S/G2/M/G0
G1
check cond for full cell cycle
DNA synth, growth and prep
S synthesis
DNA/ Centrosome replication
G2
check conditions for mitosis
M
chr segregation/ cytokinesis
stages of golgi
golgi ribbon G1/S
stack assembly G2
vesiculation M
CdK regulators
cyclins
upstream kinases
phosphatases
CdK inhib proteins
APC/ SCF
ubiquitin ligase
cov. attaches ubiquitin tag for degradation
SCF signalling
CK1 degradation to promote g1-S transition
mitogen
promotes G1/S-cyclin synthesis
DNA damage effect on cyclin activity
inhibits cyclin activity