Studies

Question 1

Which studies identify specific disease locus (frequency of alleles at marker locus compared between case and control group)

Answer 1

Association studies

Question 2

Which studies establish chromosomal location of disease locus/gene

Answer 2

Linkage studies

Question 3

Which study looks at whether familial data for disorder/trait suggests any particular mode of inheritance

Answer 3

Segregation analysis

Question 4

Which studies life time incidence of genetic disease

Answer 4

Population study

Question 5

Which studies implicate molecular pathways

Answer 5

Transgenic studies

Question 6

Which studies analyse gene function

Answer 6

Transgenesis (transfer gene from one species to another) & gene targeting

Question 7

Which studies look at whether disease is familial or not

Answer 7

Familial study