Normal Bile Composition (3)
Bile = Cholesterol, Bile Salts, Phosphatidylcholine
- Ileal Resection = xBile Salt Reabsorption = supersaturated Chol bile = Chol Stones PPT
Chemo Tx Definitions
Adjuvant = treatment given in addition to Sx NeoAdjuvant = treatment given just before surgery
Induction (initial dose killing to ≤5% tumor burden) –> Consolidation (further decrease burden) –> Maintenance (kill residual tumor to keep in remission)
Salvage: tx for disease after above standard regimens fail
MCC Syrinx (2)
Paralytic Ileus: 2 MCC
Paralytic Ileus: complete distention of SI and LI (no bowel sounds)
vs. SBO: just distention of SI (think hyperactive bowel sounds)
vs. Ogilve’s: just large intestine
CAE Indications (2)
What to do for patients with stenosis who don’t meet criteria?
CAE in:
If less, start ASA + Statin
4 Complications of PUD, Indicate MC*
Hemorrhage*
Perforation
Obstruction (Gastric Outlet)
Penetration
MC Thyroid Nodule
5 Thyroid Malignancies (MC –> LC)
Colloid
Papillary, Follicular, Medullary, Anaplastic, Lymphoma
MCCOD in Burn Patient
- with inadequate resuscitation = Hypovolemic Shock
2x Reasons Ventilation hastens death in hypovolemic shock?
DPA+ (2)
DPL+ (2)
DPA+ = 10cc gross blood + feculent matter DPL+ = ≥100K RBC, ≥500 WBC
FAST shows fluid around spleen. Next step based on ___.
HDS
The reason is to try and avoid splenectomy at all costs for immune function, especially in kids.
Erectile Dysfunction s/p Trauma (2)
Neurogenic: a/w urethral injuries
Venogenic: a/w penile fracture (b/c tunica albuginea, where veins are, are damaged)
Early vs. Late Prosthetic Infection
Pt with breast cancer, wanting to start traztuzamab. Before doing so, need ____.
ECHO; cardiotoxic
Suspected Melanoma
2 Fx of CO on O2-Dissociation Curve
5 Things that Shift Curve to Right
CO: Left Shift (b/c CO increase Hb affinity for CO AND for O2) and ∆Curve Shape
*Both decrease O2 delivery to tissue
Shift Curve Right = CBEAT
**All things increase pO2 requirement to saturate Hb, making it easier to deliver O2 to tissues
Respiratory Quotient
*guide nutrition in ICU patients
Acute Mediastinitis
MCC = intraop infection of sternotomy wound + s/p esophageal rupture
P/w = purulent drainage from sternum
CXR finding = wide anterior mediastinum
Tx = Immediate Debridement + WOUND CLOSURE + Long term antibiotics
3 Signs of Tracheobronchial Performation + Management
Management = ABCs —> Bronch to locate injury —> repair
Uncomplicated vs. Complicated Diverticulitis Def + Management
When is colonic resection indicated? (4)
Central Cord Syndrome
xMotor in arms, ok in legs (b/c morphology of fibers in CST with arms being more central)
Esophageal Varices
Insulinoma (3) vs. Glucagonoma (4) Presentation. Tx of inoperable glucagonoma (2)?
Insulinoma = Whipple Triad
Glucagonoma = 4Ds
Tx
Early vs. Late Dumping Syndrome
Early
Late